Reaction profile

The FDA adverse-event record for pustular skin eruption

96 FDA adverse-event reports reference pustular skin eruption (VeDDRA 1715). Plate codes and volume neighbourhood below; species, breeds, and drugs follow.

#1416 of 2,481
by report volume (all reactions)
96
reports citing this reaction
6.3%
death-coded share
Dog
most-affected species

Release-over-release change

What changed in the latest FDA data snapshot

PlainBreed reconstructed the prior snapshot from dated openFDA partitions through 2025 Q4, then compared it with the 2026-07-27 openFDA export. Pustular skin eruption has 96 reports now versus 96 in that prior snapshot: 0 the same number of (0.0%).

Report change
+0
Death-coded reports
+0
Death-coded share
+0.0 pts

This compares reported-event counts in two source snapshots. It does not establish a change in real-world risk, product safety, or disease incidence.

Subscribe to Pustular skin eruption changes

FDA AER · VeDDRA plate

Code 1715 VOL-LOW

VOL-LOW · DEATH-PAR · MID-PACK · PHOTO-FINISH · SPECIES-DOG · DRUG-LEAD · DESK-WIDE · BOOK-FULL

  • VOL-LOW 96 reports
  • DEATH-PAR 6.3%
  • MID-PACK #1416/2481
  • PHOTO-FINISH Cardiac failure
  • SPECIES-DOG Dog · 89
  • DRUG-LEAD Oclacitinib Malea… · 14
  • DESK-WIDE 20 breeds
  • BOOK-FULL 8/8 fields

Nearest volume peer: Cardiac failure (±0 reports)

Instrument codes from this reaction’s FDA CVM adverse-event extract: volume band, death-coded share, corpus rank, photo-finish peer, lead species, lead drug, breed desk, and book completeness. Not a clinical diagnosis.

Report-volume neighbourhood around Pustular skin eruption

Highest and lowest poles plus nearest volume peers, not a full 2,500-reaction corpus board reprint.

Vomiting · highest174348Cardiac failure · near96Foam in the nose · near96Injection site nodule · near96Pustular skin eruption · thi…96Seroma · near96Urinary tract neoplas… · low…10
FDA AER report volume · neighbourhood around Pustular skin eruption

Pustular skin eruption: low death-coded share in the FDA AER plate

Signature read: Pustular skin eruption's 6.3% death-coded share is among the lowest in the openFDA reaction corpus. Report volume sits in the middle third of the reaction corpus. Death-coded share is lower-third: 6 of 96 reports (6.3% of named reports). Nearest volume peer: Cardiac failure (±0 reports). Lead species Dog (89). Lead co-reported drug Oclacitinib Maleate (14).

Read these counts as reporting volume, not risk: per our methodology, Lead co-reported drug Oclacitinib Maleate appears in filings alongside this reaction; that is association, not causation. Browse the full reactions index or the about page for how PlainBreed frames FDA CVM extracts.

Species Most Affected

Dog 89
Cat 6
Cattle 1

Breeds Most Affected

Crossbred Canine/dog 8
Retriever - Labrador 6
Retriever - Golden 5
Shepherd Dog - German 5
Domestic Shorthair 5
Schnauzer - Miniature 3
Maltese 3
Bulldog - French 3
Dog (unknown) 3
Pinscher - Miniature 3

Associated Drugs

Oclacitinib Maleate 14
Trilostane 10
Milbemycin Oxime + Spinosad 9
Bedinvetmab 8
Spinosad 7
Afoxolaner 7
Moxidectin 6
Anti-Il31 Mab Mcs Lot #1283563 5
Grapiprant 5
Cefpodoxime Proxetil 4
Gabapentin 4
Cephalexin 3
Ivermectin + Pyrantel As Pamoate Salt 3
Sarolaner 3
Estriol 3
Gentamicin, Mometasone, Clotrimazole 3
Rabies Vaccine 2
Carprofen 2
Ivermectin + Pyrantel Pamoate 2
Afoxolaner 2.27% Chewable Tablet (68 Mg) 2

Nationwide reactions with similar profiles

Two openFDA-derived peer sets for Pustular skin eruption, both floored at ≥50 reports so the neighborhoods stay in the advertised mass (the volume chart above is the unfloored photo-finish strip).

Similar report volume

Nearest other reactions by FDA report count (96 here).

Similar death-coded share

Nearest other reactions by death-coded share (6.3% here), distinct from the volume row.

What to do with this reaction

A report does not prove a drug caused the reaction; consult a veterinarian before acting on this data.

Source: FDA Center for Veterinary Medicine openFDA Animal & Veterinary Adverse Events (CVM AER) · 2025

openFDA Animal & Veterinary Adverse Events (FDA CVM) for Pustular skin eruption (#1416 of 2,481 by report volume); death-coded 6.3%. PlainBreed reaction plate · death-coded share stamp 6.3% · vintage 2025.

Informational only. FDA adverse-event reports are voluntary and do not prove causation; consult a veterinarian before acting on them. Verify with FDA CVM →