Reaction profile

The FDA adverse-event record for hind limb paralysis

1,193 FDA reports name hind limb paralysis, a high-volume reaction in the CVM extract (VeDDRA 2025). Plate stamps and neighbourhood peers follow.

#340 of 2,481
by report volume (all reactions)
1,193
reports citing this reaction
37.8%
death-coded share
Dog
most-affected species

Release-over-release change

What changed in the latest FDA data snapshot

PlainBreed reconstructed the prior snapshot from dated openFDA partitions through 2025 Q4, then compared it with the 2026-07-27 openFDA export. Hind limb paralysis has 1,193 reports now versus 1,166 in that prior snapshot: 27 more (2.3%).

Report change
+27
Death-coded reports
+12
Death-coded share
+0.2 pts

This compares reported-event counts in two source snapshots. It does not establish a change in real-world risk, product safety, or disease incidence.

Subscribe to Hind limb paralysis changes

FDA AER · VeDDRA plate

Code 2025 VOL-MID

VOL-MID · DEATH-HOT · UPPER-Q · PHOTO-FINISH · SPECIES-DOG · DRUG-LEAD · DESK-WIDE · BOOK-FULL

  • VOL-MID 1,193 reports
  • DEATH-HOT 37.8%
  • UPPER-Q #340/2481
  • PHOTO-FINISH Bone and joint disord…
  • SPECIES-DOG Dog · 953
  • DRUG-LEAD Bedinvetmab · 248
  • DESK-WIDE 20 breeds
  • BOOK-FULL 8/8 fields

Nearest volume peer: Bone and joint disorder NOS (±4 reports)

Upper-third death-coded share drives the outcome stamps on this plate; volume band, corpus rank, and co-report peers follow. Not a clinical diagnosis.

High-volume neighbourhood around Hind limb paralysis

Upper-third volume poles plus nearest peers, not a full reaction corpus board reprint.

Vomiting · highest174348Not sleeping · near1198Hind limb paralysis · this r…1193Bone and joint disord… · near1189Eosinophilia · near1183Melaena · near1182Urinary tract neoplas… · low…10
FDA AER report volume · neighbourhood around Hind limb paralysis

Hind limb paralysis: high death-coded share in the FDA AER plate

Signature read: 451 death-coded reports is a heavy tail count for Hind limb paralysis in the CVM extract. Report volume is upper-third scale: 1,193 named reports in the openFDA extract. Death-coded share is upper-third: 451 of 1,193 reports (37.8% of named reports). Nearest volume peer: Bone and joint disorder NOS (±4 reports). Lead species Dog (953). Lead co-reported drug Bedinvetmab (248).

Read these counts as reporting volume, not risk: per our methodology, A high death-coded share in FDA filings does not prove causation; co-reporting is voluntary temporal association only. Browse the full reactions index or the about page for how PlainBreed frames FDA CVM extracts.

Species Most Affected

Dog 953
Cat 199
Cattle 14
Turkey 7
Horse 6
Pig 4
Rabbit 4
Pheasant 1
Other Bovine 1
Other Birds 1

Breeds Most Affected

Retriever - Labrador 100
Domestic Shorthair 99
Crossbred Canine/dog 60
Shepherd Dog - German 55
Dog (unknown) 51
Chihuahua 43
Retriever - Golden 40
Shih Tzu 28
Shepherd Dog - Australian 25
Dachshund (unspecified) 24

Associated Drugs

Bedinvetmab 248
Carprofen 144
Gabapentin 106
Milbemycin Oxime + Spinosad 90
Afoxolaner 65
Frunevetmab 51
Melarsomine Dihydrochloride 43
Cefovecin 43
Pyrantel Pamoate;Sarolaner 43
Moxidectin 41
Prednisone 40
Maropitant Citrate 36
Sarolaner 36
Ivermectin + Pyrantel As Pamoate Salt 35
Spinosad 33
Selamectin 32
Fluralaner 13.64% 12-Week Chew 32
Enrofloxacin 27
Meloxicam 27
Grapiprant 25

Nationwide reactions with similar profiles

Two openFDA-derived peer sets for Hind limb paralysis, both floored at ≥50 reports so the neighborhoods stay in the advertised mass (the volume chart above is the unfloored photo-finish strip).

Similar report volume

Nearest other reactions by FDA report count (1,193 here).

Similar death-coded share

Nearest other reactions by death-coded share (37.8% here), distinct from the volume row.

What to do with this reaction

A report does not prove a drug caused the reaction; consult a veterinarian before acting on this data.

Source: FDA Center for Veterinary Medicine openFDA Animal & Veterinary Adverse Events (CVM AER) · 2025

openFDA Animal & Veterinary Adverse Events (FDA CVM) for Hind limb paralysis (#340 of 2,481 by report volume); death-coded 37.8%. PlainBreed reaction plate · death-coded report count stamp 451 · vintage 2025.

Informational only. FDA adverse-event reports are voluntary and do not prove causation; consult a veterinarian before acting on them. Verify with FDA CVM →