Reaction profile

The FDA adverse-event record for hind limb paralysis

1,141 FDA adverse-event reports reference hind limb paralysis (VeDDRA 2025). See the species, breeds, and drugs most associated with it below.

1,141
reports citing this reaction
37.0%
death-coded share
Dog
most-affected species
Bedinvetmab
most-associated drug
Verify with FDA CVM →
1,141
Total Reports
422
Deaths
37.0%
Death Rate

Species Most Affected

Dog 915
Cat 186
Cattle 13
Turkey 7
Horse 6
Pig 4
Rabbit 4
Pheasant 1
Other Bovine 1
Other Birds 1

Breeds Most Affected

Retriever - Labrador 93
Domestic Shorthair 93
Crossbred Canine/dog 59
Shepherd Dog - German 54
Dog (unknown) 49
Chihuahua 40
Retriever - Golden 38
Shih Tzu 26
Dachshund (unspecified) 24
Boxer (German Boxer) 24

Associated Drugs

Bedinvetmab 231
Carprofen 135
Gabapentin 96
Milbemycin Oxime + Spinosad 90
Afoxolaner 62
Frunevetmab 45
Melarsomine Dihydrochloride 41
Cefovecin 41
Prednisone 40
Moxidectin 39
Pyrantel Pamoate;Sarolaner 36
Ivermectin + Pyrantel As Pamoate Salt 35
Sarolaner 35
Maropitant Citrate 34
Spinosad 33
Fluralaner 13.64% 12-Week Chew 31
Selamectin 30
Enrofloxacin 27
Meloxicam 26
Grapiprant 25

Hind limb paralysis Reaction Insights

1,141 reports name Hind limb paralysis; 422 recorded a death outcome (37.0% of reported events, not a population-level mortality rate). VeDDRA code: 2025.

By species: Dog (915 reports), Cat (186 reports), Cattle (13 reports). By breed: Retriever - Labrador (93), Domestic Shorthair (93), Crossbred Canine/dog (59).

Most co-reported drugs: Bedinvetmab (231 reports), Carprofen (135 reports), Gabapentin (96 reports), Milbemycin Oxime + Spinosad (90 reports).

Read these counts as reporting volume, not risk: per our methodology, co-reporting reflects temporal association captured in voluntary submissions, not proof that a drug caused this reaction. A widely-prescribed drug will rack up more raw co-reports at an identical true rate than a rarely-used one, so compare within similar-exposure products.

Source: FDA Center for Veterinary Medicine openFDA Animal & Veterinary Adverse Events (CVM AER) · 2025

Every figure on PlainBreed is rendered directly from FDA openFDA adverse event data, no number is typed in by an editor. This page draws directly on FDA openFDA data, no figure is typed in by an editor. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.