Thyroidititis

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VeDDRA Code: 1839

12 adverse event reports referencing this reaction

12
Total Reports
9
Deaths
7500.0%
Death Rate

Species Most Affected

Dog 10
Tiger 1
Human 1

Breeds Most Affected

Boxer (German Boxer) 4
Retriever - Golden 2
Unknown 2
Crossbred Canine/dog 1
Schnauzer - Giant 1
Dog (other) 1
Deutsche Dogge, Great Dane 1

Associated Drugs

Milbemycin Oxime + Spinosad 4
Milbemycin Oxime 3
Ivermectin 2
Recombinant Human Insulin 1
Carprofen 1
Tris-Edta, Otic 1
Gentamicin Sulfate, Topical 1
Deracoxib 1
Butorphanol Tartrate 1
Dexmedetomidine 1
Grapiprant 1
Zonisamide 1
Oclacitinib Maleate 1
Fluralaner Chew Tablets 1
Moxidectin 1
Mirtazapine 1
Cefovecin Sodium 1
Enrofloxacin 1
Penicillin G 1
Thiamazole 1

Data Summary

Metric Value
Total reports referencing reaction 12
Reports with fatal outcome 9
Case-fatality rate (reported events) 7500.0%
Species observed 3
Breeds observed 7
Drugs associated with reaction 20

Source: FDA Center for Veterinary Medicine — Adverse Event Reporting (CVM AER); reaction term coded under VeDDRA 1839.

Thyroidititis Reaction Insights

The FDA Center for Veterinary Medicine database currently lists 12 adverse event reports that reference Thyroidititis as a reaction term, including 9 reports with a death outcome — a 7500.0% case-fatality figure calculated across only those events where this reaction was coded. The reaction is indexed in the openFDA system under VeDDRA code 1839, the standardized veterinary dictionary used to normalize clinical signs across submitters. Because reports are voluntary and often describe multiple concurrent signs per animal, the volume here reflects reporting intensity rather than true incidence in the broader pet population.

Thyroidititis appears most frequently in reports for Dog (10 reports), Tiger (1 reports), Human (1 reports) — with Dog dominating at 10 entries. Within those species, the breeds most often named alongside this reaction are Boxer (German Boxer) (4), Retriever - Golden (2), Unknown (2). These distributions are influenced both by underlying breed popularity and by how veterinarians and owners code a given clinical sign, so they should be interpreted as a reporting fingerprint rather than a pure susceptibility ranking.

The drugs most commonly co-reported with Thyroidititis are Milbemycin Oxime + Spinosad (4 reports), Milbemycin Oxime (3 reports), Ivermectin (2 reports), Recombinant Human Insulin (1 reports), with Milbemycin Oxime + Spinosad appearing alongside this reaction in 4 submissions. Co-reporting does not establish that any specific product caused the reaction — FDA CVM data captures temporal association only. The value of these aggregates is in flagging which therapeutic classes appear repeatedly alongside a given clinical sign, so owners and veterinarians can ask targeted questions about medications currently in use.

Source: FDA Center for Veterinary Medicine — Adverse Event Reports FDA Center for Veterinary Medicine — Adverse Event Reports Data reflects voluntary submissions and may not represent actual incidence rates

Related

Data sourced from official AKC, AVMA, ACVO, and breed-club veterinary references. See our methodology for details. Retrieved and formatted by PlainBreed Editorial