Reaction profile

The FDA adverse-event record for spherocytosis

55 FDA adverse-event reports reference spherocytosis (VeDDRA 2612). See the species, breeds, and drugs most associated with it below.

55
reports citing this reaction
29.1%
death-coded share
Dog
most-affected species
Maropitant Citrate
most-associated drug
Verify with FDA CVM →
55
Total Reports
16
Deaths
29.1%
Death Rate

Species Most Affected

Dog 53
Cat 2

Breeds Most Affected

Shih Tzu 5
Crossbred Canine/dog 5
Spitz - German Pomeranian 4
Spaniel (unspecified) 3
Retriever - Labrador 3
Retriever - Golden 3
Shepherd Dog - Australian 2
Collie - Border 2
Corgi - Welsh Pembroke 2
Terrier - Rat 1

Associated Drugs

Maropitant Citrate 12
Moxidectin 12
Carprofen 9
Prednisone 7
Fluralaner Chew Tablets 7
Doxycycline 5
Sarolaner 5
Anti-Il31 Mab Mcs Lot #1283563 5
Gabapentin 5
Ivermectin 4
Rabies Virus, 4
Enrofloxacin 4
Bordetella Bronchiseptica, Strain 78-9159 3
Famotidine 3
Omeprazole 3
Ivermectin + Pyrantel As Pamoate Salt 3
Leptospira Canicola L-15 Strain C-51;Leptospira Grippotyphosa 1550 Lot 10005 Str 3
Cefpodoxime Proxetil 3
Pyrantel Pamoate;Sarolaner 3
Bedinvetmab 3

Spherocytosis Reaction Insights

55 reports name Spherocytosis; 16 recorded a death outcome (29.1% of reported events, not a population-level mortality rate). VeDDRA code: 2612.

By species: Dog (53 reports), Cat (2 reports). By breed: Shih Tzu (5), Crossbred Canine/dog (5), Spitz - German Pomeranian (4).

Most co-reported drugs: Maropitant Citrate (12 reports), Moxidectin (12 reports), Carprofen (9 reports), Prednisone (7 reports).

Read these counts as reporting volume, not risk: per our methodology, co-reporting reflects temporal association captured in voluntary submissions, not proof that a drug caused this reaction. A widely-prescribed drug will rack up more raw co-reports at an identical true rate than a rarely-used one, so compare within similar-exposure products.

Source: FDA Center for Veterinary Medicine openFDA Animal & Veterinary Adverse Events (CVM AER) · 2025

Every figure on PlainBreed is rendered directly from FDA openFDA adverse event data, no number is typed in by an editor. This page draws directly on FDA openFDA data, no figure is typed in by an editor. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.