Reaction profile

The FDA adverse-event record for spherocytosis

64 FDA adverse-event reports reference spherocytosis (VeDDRA 2612). Plate codes and volume neighbourhood below; species, breeds, and drugs follow.

#1623 of 2,481
by report volume (all reactions)
64
reports citing this reaction
31.3%
death-coded share
Dog
most-affected species

Release-over-release change

What changed in the latest FDA data snapshot

PlainBreed reconstructed the prior snapshot from dated openFDA partitions through 2025 Q4, then compared it with the 2026-07-27 openFDA export. Spherocytosis has 64 reports now versus 58 in that prior snapshot: 6 more (10.3%).

Report change
+6
Death-coded reports
+2
Death-coded share
+0.2 pts

This compares reported-event counts in two source snapshots. It does not establish a change in real-world risk, product safety, or disease incidence.

Subscribe to Spherocytosis changes

FDA AER · VeDDRA plate

Code 2612 VOL-LOW

VOL-LOW · DEATH-HOT · MID-PACK · PHOTO-FINISH · SPECIES-DOG · DRUG-LEAD · DESK-WIDE · BOOK-FULL

  • VOL-LOW 64 reports
  • DEATH-HOT 31.3%
  • MID-PACK #1623/2481
  • PHOTO-FINISH Lacrimation
  • SPECIES-DOG Dog · 62
  • DRUG-LEAD Maropitant Citrate · 17
  • DESK-WIDE 20 breeds
  • BOOK-FULL 8/8 fields

Nearest volume peer: Lacrimation (±0 reports)

Upper-third death-coded share drives the outcome stamps on this plate; volume band, corpus rank, and co-report peers follow. Not a clinical diagnosis.

Report-volume neighbourhood around Spherocytosis

Highest and lowest poles plus nearest volume peers, not a full 2,500-reaction corpus board reprint.

Vomiting · highest174348Acne · near65Lacrimation · near64Preputial discharge · near64Snoring · near64Spherocytosis · this reaction64Urinary tract neoplas… · low…10
FDA AER report volume · neighbourhood around Spherocytosis

Spherocytosis: high death-coded share in the FDA AER plate

Signature read: Spherocytosis's 31.3% death-coded share is among the highest in the openFDA reaction corpus. Report volume sits in the middle third of the reaction corpus. Death-coded share is upper-third: 20 of 64 reports (31.3% of named reports). Nearest volume peer: Lacrimation (±0 reports). Lead species Dog (62). Lead co-reported drug Maropitant Citrate (17).

Read these counts as reporting volume, not risk: per our methodology, A high death-coded share in FDA filings does not prove causation; co-reporting is voluntary temporal association only. Browse the full reactions index or the about page for how PlainBreed frames FDA CVM extracts.

Species Most Affected

Dog 62
Cat 2

Breeds Most Affected

Shih Tzu 6
Crossbred Canine/dog 6
Spitz - German Pomeranian 4
Retriever - Labrador 4
Spaniel (unspecified) 3
Retriever - Golden 3
Shepherd Dog - Australian 2
Shepherd Dog - German 2
Collie - Border 2
Corgi - Welsh Pembroke 2

Associated Drugs

Maropitant Citrate 17
Moxidectin 13
Carprofen 9
Doxycycline 8
Prednisone 8
Fluralaner Chew Tablets 7
Gabapentin 7
Bordetella Bronchiseptica, Strain 78-9159 5
Sarolaner 5
Anti-Il31 Mab Mcs Lot #1283563 5
Cyclosporine 5
Bedinvetmab 5
Ivermectin 4
Rabies Virus, 4
Fluralaner 4
Enrofloxacin 4
Pyrantel Pamoate;Sarolaner 4
Dexamethasone 3
Famotidine 3
Omeprazole 3

Nationwide reactions with similar profiles

Two openFDA-derived peer sets for Spherocytosis, both floored at ≥50 reports so the neighborhoods stay in the advertised mass (the volume chart above is the unfloored photo-finish strip).

Similar report volume

Nearest other reactions by FDA report count (64 here).

Similar death-coded share

Nearest other reactions by death-coded share (31.3% here), distinct from the volume row.

What to do with this reaction

A report does not prove a drug caused the reaction; consult a veterinarian before acting on this data.

Source: FDA Center for Veterinary Medicine openFDA Animal & Veterinary Adverse Events (CVM AER) · 2025

openFDA Animal & Veterinary Adverse Events (FDA CVM) for Spherocytosis (#1623 of 2,481 by report volume); death-coded 31.3%. PlainBreed reaction plate · death-coded share stamp 31.3% · vintage 2025.

Informational only. FDA adverse-event reports are voluntary and do not prove causation; consult a veterinarian before acting on them. Verify with FDA CVM →