Reaction profile

The FDA adverse-event record for purpura

Name: Purpura - FDA Animal Adverse Reaction
Creator: PlainBreed
License: https://open.fda.gov/license/

22 FDA reports name purpura, a lower-volume reaction in the CVM extract (VeDDRA 1714). Plate stamps and neighbourhood peers follow.

#2135 of 2,481
by report volume (all reactions): 22
reports citing this reaction: 31.8%
death-coded share: Dog
most-affected species

Compiled by PlainBreed

Verify with FDA CVM →

Release-over-release change

What changed in the latest FDA data snapshot

PlainBreed reconstructed the prior snapshot from dated openFDA partitions through 2025 Q4, then compared it with the 2026-07-27 openFDA export. Purpura has 22 reports now versus 22 in that prior snapshot: 0 the same number of (0.0%).

Report change: +0
Death-coded reports: +0
Death-coded share: −0.0 pts

This compares reported-event counts in two source snapshots. It does not establish a change in real-world risk, product safety, or disease incidence.

Subscribe to Purpura changes

FDA AER · VeDDRA plate

Code 1714 VOL-TRACE

VOL-TRACE · DEATH-HOT · LOWER-Q · PHOTO-FINISH · SPECIES-DOG · DRUG-LEAD · DESK-WIDE · BOOK-FULL

VOL-TRACE 22 reports
DEATH-HOT 31.8%
LOWER-Q #2135/2481
PHOTO-FINISH Adenocarcinoma NOS
SPECIES-DOG Dog · 17
DRUG-LEAD Trilostane · 4
DESK-WIDE 18 breeds
BOOK-FULL 8/8 fields

Nearest volume peer: Adenocarcinoma NOS (±0 reports)

Upper-third death-coded share drives the outcome stamps on this plate; volume band, corpus rank, and co-report peers follow. Not a clinical diagnosis.

Lower-volume neighbourhood around Purpura

Lower-third volume poles plus nearest peers, not a full reaction corpus board reprint.

FDA AER report volume · neighbourhood around Purpura

Purpura: high death-coded share in the FDA AER plate

Signature read: 22 reports place Purpura in the lower third of FDA AER volume (#2135 of 2,481). Report volume is lower-third scale: 22 named reports in the openFDA extract. Death-coded share is upper-third: 7 of 22 reports (31.8% of named reports). Nearest volume peer: Adenocarcinoma NOS (±0 reports). Lead species Dog (17). Lead co-reported drug Trilostane (4).

Read these counts as reporting volume, not risk: per our methodology, A high death-coded share in FDA filings does not prove causation; co-reporting is voluntary temporal association only. Browse the full reactions index or the about page for how PlainBreed frames FDA CVM extracts.

Species Most Affected

Dog 17

Horse 4

Cattle 1

Breeds Most Affected

Retriever - Labrador 3

Chihuahua 2

Paint 2

Warmblood - Dutch 1

Terrier (unspecified) 1

Cattle (unknown) 1

Rottweiler 1

Spaniel (unspecified) 1

Deutsche Dogge, Great Dane 1

Dog (other) 1

Associated Drugs

Trilostane 4

Dexmedetomidine Hydrochloride 3

Clindamycin 3

Prednisone 3

Milbemycin Oxime + Spinosad 2

Isoflurane 2

Cefazolin 2

Afoxolaner 2

Florfenicol + Mometasone Furoate + Terbinafine Hydrochloride 2

Ivermectin 2

Diphenhydramine 2

Atipamezole Hydrochloride 2

Ceftiofur Crystalline Free Acid 2

Ivermectin(1.55%)/Praziquantel(7.75%) Paste 1

Eprinomectin 1

Rabies Vaccine 1

Afoxolaner 68 Mg Chewable Tablets 1

Butorphanol Tartrate 1

Carprofen 1

Rabies Virus, Kv 1

What to do with this reaction

Read how death-coded share differs from a mortality rate before drawing conclusions. Understanding adverse events
Browse the full reaction directory to compare report counts across reaction types. All reactions

A report does not prove a drug caused the reaction; consult a veterinarian before acting on this data.

Source: FDA Center for Veterinary Medicine openFDA Animal & Veterinary Adverse Events (CVM AER) · 2025

openFDA Animal & Veterinary Adverse Events (FDA CVM) for Purpura (#2135 of 2,481 by report volume); death-coded 31.8%. PlainBreed reaction plate · report volume stamp 22 · vintage 2025.

Informational only. FDA adverse-event reports are voluntary and do not prove causation; consult a veterinarian before acting on them. Verify with FDA CVM →