Reaction profile

The FDA adverse-event record for tic(s)

Name: Tic(s) - FDA Animal Adverse Reaction
Creator: PlainBreed
License: https://open.fda.gov/license/

47 FDA reports name tic(s), a lower-volume reaction in the CVM extract (VeDDRA 685). Plate stamps and neighbourhood peers follow.

#1779 of 2,481
by report volume (all reactions): 47
reports citing this reaction: 4.3%
death-coded share: Dog
most-affected species

Compiled by PlainBreed

Verify with FDA CVM →

Release-over-release change

What changed in the latest FDA data snapshot

PlainBreed reconstructed the prior snapshot from dated openFDA partitions through 2025 Q4, then compared it with the 2026-07-27 openFDA export. Tic(s) has 47 reports now versus 47 in that prior snapshot: 0 the same number of (0.0%).

Report change: +0
Death-coded reports: +0
Death-coded share: +0.0 pts

This compares reported-event counts in two source snapshots. It does not establish a change in real-world risk, product safety, or disease incidence.

Subscribe to Tic(s) changes

FDA AER · VeDDRA plate

Code 685 VOL-TRACE

VOL-TRACE · DEATH-LOW · MID-PACK · PHOTO-FINISH · SPECIES-DOG · DRUG-LEAD · DESK-WIDE · BOOK-FULL

VOL-TRACE 47 reports
DEATH-LOW 4.3%
MID-PACK #1779/2481
PHOTO-FINISH Abnormal number of of…
SPECIES-DOG Dog · 42
DRUG-LEAD Sarolaner · 13
DESK-WIDE 20 breeds
BOOK-FULL 8/8 fields

Nearest volume peer: Abnormal number of offspring (±0 reports)

Instrument codes from this reaction’s FDA CVM adverse-event extract: volume band, death-coded share, corpus rank, photo-finish peer, lead species, lead drug, breed desk, and book completeness. Not a clinical diagnosis.

Lower-volume neighbourhood around Tic

Lower-third volume poles plus nearest peers, not a full reaction corpus board reprint.

FDA AER report volume · neighbourhood around Tic(s)

Tic(s): low death-coded share in the FDA AER plate

Signature read: 2 death-coded reports is a thin tail count for Tic(s) in the CVM extract. Report volume is lower-third scale: 47 named reports in the openFDA extract. Death-coded share is lower-third: 2 of 47 reports (4.3% of named reports). Nearest volume peer: Abnormal number of offspring (±0 reports). Lead species Dog (42). Lead co-reported drug Sarolaner (13).

Read these counts as reporting volume, not risk: per our methodology, Lead co-reported drug Sarolaner appears in filings alongside this reaction; that is association, not causation. Browse the full reactions index or the about page for how PlainBreed frames FDA CVM extracts.

Species Most Affected

Dog 42

Cat 4

Rabbit 1

Breeds Most Affected

Retriever - Labrador 10

Boxer (German Boxer) 3

Terrier - Yorkshire 3

Retriever - Golden 3

Dachshund (unspecified) 2

Schnauzer - Miniature 2

Spaniel (unspecified) 2

Domestic Shorthair 2

American Pit Bull Terrier 1

Dog (other) 1

Associated Drugs

Sarolaner 13

Milbemycin Oxime + Spinosad 10

Carprofen 7

Pyrantel Pamoate;Sarolaner 5

Bedinvetmab 5

Gabapentin 4

Spinosad 3

Ivermectin 2

Maropitant Citrate 2

Meloxicam 2

Cyclosporine 2

Clomipramine 2

Prednisone 2

Pregabalin 2

Ivermectin 272Mcg, Pyrantel 227Mg 1

Furosemide 1

Pimobendan 1

Prednisolone Trimeprazine Tartrate 1

Cephalexin 1

Phycocyanin + Glucosamine + Methylsulfonylmethane + Minerals + Essential Fatty Acids 1

What to do with this reaction

Read how death-coded share differs from a mortality rate before drawing conclusions. Understanding adverse events
Browse the full reaction directory to compare report counts across reaction types. All reactions

A report does not prove a drug caused the reaction; consult a veterinarian before acting on this data.

Source: FDA Center for Veterinary Medicine openFDA Animal & Veterinary Adverse Events (CVM AER) · 2025

openFDA Animal & Veterinary Adverse Events (FDA CVM) for Tic(s) (#1779 of 2,481 by report volume); death-coded 4.3%. PlainBreed reaction plate · death-coded report count stamp 2 · vintage 2025.

Informational only. FDA adverse-event reports are voluntary and do not prove causation; consult a veterinarian before acting on them. Verify with FDA CVM →