Reaction profile

The FDA adverse-event record for sight affected

52 FDA reports name sight affected, a lower-volume reaction in the CVM extract (VeDDRA 408). Plate stamps and neighbourhood peers follow.

#1722 of 2,481
by report volume (all reactions)
52
reports citing this reaction
21.2%
death-coded share
Dog
most-affected species

Release-over-release change

What changed in the latest FDA data snapshot

PlainBreed reconstructed the prior snapshot from dated openFDA partitions through 2025 Q4, then compared it with the 2026-07-27 openFDA export. Sight affected has 52 reports now versus 50 in that prior snapshot: 2 more (4.0%).

Report change
+2
Death-coded reports
+0
Death-coded share
−0.8 pts

This compares reported-event counts in two source snapshots. It does not establish a change in real-world risk, product safety, or disease incidence.

Subscribe to Sight affected changes

FDA AER · VeDDRA plate

Code 408 VOL-LOW

VOL-LOW · DEATH-HOT · MID-PACK · PHOTO-FINISH · SPECIES-DOG · DRUG-LEAD · DESK-WIDE · BOOK-FULL

  • VOL-LOW 52 reports
  • DEATH-HOT 21.2%
  • MID-PACK #1722/2481
  • PHOTO-FINISH Decreased intra-ocula…
  • SPECIES-DOG Dog · 43
  • DRUG-LEAD Bedinvetmab · 8
  • DESK-WIDE 20 breeds
  • BOOK-FULL 8/8 fields

Nearest volume peer: Decreased intra-ocular pressure (±0 reports)

Instrument codes from this reaction’s FDA CVM adverse-event extract: volume band, death-coded share, corpus rank, photo-finish peer, lead species, lead drug, breed desk, and book completeness. Not a clinical diagnosis.

Lower-volume neighbourhood around Sight affected

Lower-third volume poles plus nearest peers, not a full reaction corpus board reprint.

Vomiting · highest174348Decreased intra-ocula… · near52Hypersensitivity to p… · near52Impurity · near52Injection site haemor… · near52Sight affected · this reacti…52Urinary tract neoplas… · low…10
FDA AER report volume · neighbourhood around Sight affected

What the FDA AER plate says about Sight affected

Signature read: 52 reports place Sight affected in the lower third of FDA AER volume (#1722 of 2,481). Report volume is lower-third scale: 52 named reports in the openFDA extract. 11 of 52 reports were death-coded (21.2% of named reports, not a population mortality rate). Nearest volume peer: Decreased intra-ocular pressure (±0 reports). Lead species Dog (43). Lead co-reported drug Bedinvetmab (8).

Read these counts as reporting volume, not risk: per our methodology, Lead co-reported drug Bedinvetmab appears in filings alongside this reaction; that is association, not causation. Browse the full reactions index or the about page for how PlainBreed frames FDA CVM extracts.

Species Most Affected

Dog 43
Cat 8
Cattle 1

Breeds Most Affected

Dog (unknown) 4
Domestic Shorthair 4
Shepherd Dog - Australian 3
Pug 3
Terrier (unspecified) 3
Chow Chow 3
Boxer (German Boxer) 2
Retriever - Labrador 2
Domestic Longhair 2
Chihuahua 2

Associated Drugs

Bedinvetmab 8
Milbemycin Oxime + Spinosad 6
Spinosad 5
Afoxolaner 4
Fluralaner 13.64% 12-Week Chew 4
Cefovecin 3
Carprofen 2
Enrofloxacin 2
Sarolaner 2
Robenacoxib 2
Oclacitinib Maleate 2
Galliprant 2
Adequan 2
Optimmune 2
Erythromycin 2
Anti-Il31 Mab Mcs Lot #1283563 2
Pro-In 2
Ear Medications 2
Rabies Vaccination 2
Milbemycin Oxime 1

Nationwide reactions with similar profiles

Two openFDA-derived peer sets for Sight affected, both floored at ≥50 reports so the neighborhoods stay in the advertised mass (the volume chart above is the unfloored photo-finish strip).

Similar report volume

Nearest other reactions by FDA report count (52 here).

Similar death-coded share

Nearest other reactions by death-coded share (21.2% here), distinct from the volume row.

What to do with this reaction

A report does not prove a drug caused the reaction; consult a veterinarian before acting on this data.

Source: FDA Center for Veterinary Medicine openFDA Animal & Veterinary Adverse Events (CVM AER) · 2025

openFDA Animal & Veterinary Adverse Events (FDA CVM) for Sight affected (#1722 of 2,481 by report volume); death-coded 21.2%. PlainBreed reaction plate · report volume stamp 52 · vintage 2025.

Informational only. FDA adverse-event reports are voluntary and do not prove causation; consult a veterinarian before acting on them. Verify with FDA CVM →