Reaction profile

The FDA adverse-event record for sight affected

49 FDA adverse-event reports reference sight affected (VeDDRA 408). See the species, breeds, and drugs most associated with it below.

49
reports citing this reaction
20.4%
death-coded share
Dog
most-affected species
Bedinvetmab
most-associated drug
Verify with FDA CVM →
49
Total Reports
10
Deaths
20.4%
Death Rate

Species Most Affected

Dog 41
Cat 7
Cattle 1

Breeds Most Affected

Dog (unknown) 4
Domestic Shorthair 4
Shepherd Dog - Australian 3
Pug 3
Chow Chow 3
Boxer (German Boxer) 2
Retriever - Labrador 2
Domestic Longhair 2
Chihuahua 2
Terrier - Jack Russell 2

Associated Drugs

Bedinvetmab 7
Milbemycin Oxime + Spinosad 6
Spinosad 5
Afoxolaner 4
Fluralaner 13.64% 12-Week Chew 4
Cefovecin 3
Carprofen 2
Enrofloxacin 2
Sarolaner 2
Robenacoxib 2
Oclacitinib Maleate 2
Optimmune 2
Galliprant 2
Adequan 2
Erythromycin 2
Anti-Il31 Mab Mcs Lot #1283563 2
Pro-In 2
Ear Medications 2
Rabies Vaccination 2
Milbemycin Oxime 1

Sight affected Reaction Insights

49 reports name Sight affected; 10 recorded a death outcome (20.4% of reported events, not a population-level mortality rate). VeDDRA code: 408.

By species: Dog (41 reports), Cat (7 reports), Cattle (1 reports). By breed: Dog (unknown) (4), Domestic Shorthair (4), Shepherd Dog - Australian (3).

Most co-reported drugs: Bedinvetmab (7 reports), Milbemycin Oxime + Spinosad (6 reports), Spinosad (5 reports), Afoxolaner (4 reports).

Read these counts as reporting volume, not risk: per our methodology, co-reporting reflects temporal association captured in voluntary submissions, not proof that a drug caused this reaction. A widely-prescribed drug will rack up more raw co-reports at an identical true rate than a rarely-used one, so compare within similar-exposure products.

Source: FDA Center for Veterinary Medicine openFDA Animal & Veterinary Adverse Events (CVM AER) · 2025

Every figure on PlainBreed is rendered directly from FDA openFDA adverse event data, no number is typed in by an editor. This page draws directly on FDA openFDA data, no figure is typed in by an editor. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.