Reaction profile

The FDA adverse-event record for acidosis

225 FDA adverse-event reports reference acidosis (VeDDRA 1898). See the species, breeds, and drugs most associated with it below.

225
reports citing this reaction
43.1%
death-coded share
Dog
most-affected species
Maropitant Citrate
most-associated drug
Verify with FDA CVM →
225
Total Reports
97
Deaths
43.1%
Death Rate

Species Most Affected

Dog 143
Cat 56
Cattle 8
Horse 6
Human 2
Jaguar 2
Mouse 1
Llama 1
Camel 1
Tiger 1

Breeds Most Affected

Domestic Shorthair 34
Crossbred Canine/dog 14
Retriever - Labrador 11
Unknown 10
Retriever - Golden 9
Maltese 7
Chihuahua 7
Terrier - Airedale 6
Domestic (unspecified) 6
Shih Tzu 5

Associated Drugs

Maropitant Citrate 23
Bexagliflozin 18
Carprofen 16
Buprenorphine 14
Milbemycin Oxime + Spinosad 13
Isoflurane 10
Trilostane 10
Prednisone 9
Gabapentin 9
Enrofloxacin 8
Deracoxib 8
Dexmedetomidine Hydrochloride 8
Propofol 8
Fluid Therapy 8
Spinosad 7
Maropitant 7
Meloxicam 7
Moxidectin 7
Oclacitinib Maleate 7
Fluralaner Chew Tablets 7

Acidosis Reaction Insights

225 reports name Acidosis; 97 recorded a death outcome (43.1% of reported events, not a population-level mortality rate). VeDDRA code: 1898.

By species: Dog (143 reports), Cat (56 reports), Cattle (8 reports). By breed: Domestic Shorthair (34), Crossbred Canine/dog (14), Retriever - Labrador (11).

Most co-reported drugs: Maropitant Citrate (23 reports), Bexagliflozin (18 reports), Carprofen (16 reports), Buprenorphine (14 reports).

Read these counts as reporting volume, not risk: per our methodology, co-reporting reflects temporal association captured in voluntary submissions, not proof that a drug caused this reaction. A widely-prescribed drug will rack up more raw co-reports at an identical true rate than a rarely-used one, so compare within similar-exposure products.

Source: FDA Center for Veterinary Medicine openFDA Animal & Veterinary Adverse Events (CVM AER) · 2025

Every figure on PlainBreed is rendered directly from FDA openFDA adverse event data, no number is typed in by an editor. This page draws directly on FDA openFDA data, no figure is typed in by an editor. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.