Reaction profile

The FDA adverse-event record for acidosis

242 FDA adverse-event reports reference acidosis (VeDDRA 1898). Plate codes and volume neighbourhood below; species, breeds, and drugs follow.

#950 of 2,481
by report volume (all reactions)
242
reports citing this reaction
43.0%
death-coded share
Dog
most-affected species

Release-over-release change

What changed in the latest FDA data snapshot

PlainBreed reconstructed the prior snapshot from dated openFDA partitions through 2025 Q4, then compared it with the 2026-07-27 openFDA export. Acidosis has 242 reports now versus 237 in that prior snapshot: 5 more (2.1%).

Report change
+5
Death-coded reports
+2
Death-coded share
−0.1 pts

This compares reported-event counts in two source snapshots. It does not establish a change in real-world risk, product safety, or disease incidence.

Subscribe to Acidosis changes

FDA AER · VeDDRA plate

Code 1898 VOL-LOW

VOL-LOW · DEATH-HOT · MID-PACK · PHOTO-FINISH · SPECIES-DOG · DRUG-LEAD · DESK-WIDE · BOOK-FULL

  • VOL-LOW 242 reports
  • DEATH-HOT 43.0%
  • MID-PACK #950/2481
  • PHOTO-FINISH Infectious disease NOS
  • SPECIES-DOG Dog · 152
  • DRUG-LEAD Maropitant Citrate · 25
  • DESK-WIDE 20 breeds
  • BOOK-FULL 8/8 fields

Nearest volume peer: Infectious disease NOS (±0 reports)

Upper-third death-coded share drives the outcome stamps on this plate; volume band, corpus rank, and co-report peers follow. Not a clinical diagnosis.

Report-volume neighbourhood around Acidosis

Highest and lowest poles plus nearest volume peers, not a full 2,500-reaction corpus board reprint.

Vomiting · highest174348Acidosis · this reaction242Infectious disease NOS · near242Joint effusion · near242Pollakiuria · near242Unusual stool colour · near242Urinary tract neoplas… · low…10
FDA AER report volume · neighbourhood around Acidosis

Acidosis: high death-coded share in the FDA AER plate

Signature read: Acidosis's 43.0% death-coded share is among the highest in the openFDA reaction corpus. Report volume sits in the middle third of the reaction corpus. Death-coded share is upper-third: 104 of 242 reports (43.0% of named reports). Nearest volume peer: Infectious disease NOS (±0 reports). Lead species Dog (152). Lead co-reported drug Maropitant Citrate (25).

Read these counts as reporting volume, not risk: per our methodology, A high death-coded share in FDA filings does not prove causation; co-reporting is voluntary temporal association only. Browse the full reactions index or the about page for how PlainBreed frames FDA CVM extracts.

Species Most Affected

Dog 152
Cat 63
Cattle 8
Horse 6
Human 2
Jaguar 2
Lion 2
Mouse 1
Llama 1
Camel 1

Breeds Most Affected

Domestic Shorthair 38
Crossbred Canine/dog 14
Retriever - Labrador 12
Unknown 11
Retriever - Golden 9
Chihuahua 8
Maltese 7
Terrier - Airedale 6
Domestic (unspecified) 6
Terrier - Yorkshire 5

Associated Drugs

Maropitant Citrate 25
Bexagliflozin 20
Carprofen 17
Buprenorphine 14
Milbemycin Oxime + Spinosad 13
Isoflurane 12
Trilostane 11
Gabapentin 11
Maropitant 9
Meloxicam 9
Prednisone 9
Enrofloxacin 8
Dexmedetomidine Hydrochloride 8
Deracoxib 8
Propofol 8
Oclacitinib Maleate 8
Ondansetron 8
Fluid Therapy 8
Spinosad 7
Cefovecin 7

Nationwide reactions with similar profiles

Two openFDA-derived peer sets for Acidosis, both floored at ≥50 reports so the neighborhoods stay in the advertised mass (the volume chart above is the unfloored photo-finish strip).

Similar report volume

Nearest other reactions by FDA report count (242 here).

Similar death-coded share

Nearest other reactions by death-coded share (43.0% here), distinct from the volume row.

What to do with this reaction

A report does not prove a drug caused the reaction; consult a veterinarian before acting on this data.

Source: FDA Center for Veterinary Medicine openFDA Animal & Veterinary Adverse Events (CVM AER) · 2025

openFDA Animal & Veterinary Adverse Events (FDA CVM) for Acidosis (#950 of 2,481 by report volume); death-coded 43.0%. PlainBreed reaction plate · death-coded share stamp 43.0% · vintage 2025.

Informational only. FDA adverse-event reports are voluntary and do not prove causation; consult a veterinarian before acting on them. Verify with FDA CVM →