Reaction profile

The FDA adverse-event record for pr-blood vessel(s), lesion(s)

30 FDA reports name pr-blood vessel(s), lesion(s), a lower-volume reaction in the CVM extract (VeDDRA 99591). Plate stamps and neighbourhood peers follow.

#2006 of 2,481
by report volume (all reactions)
30
reports citing this reaction
80.0%
death-coded share
Dog
most-affected species

Release-over-release change

What changed in the latest FDA data snapshot

PlainBreed reconstructed the prior snapshot from dated openFDA partitions through 2025 Q4, then compared it with the 2026-07-27 openFDA export. PR-BLOOD VESSEL(S), LESION(S) has 30 reports now versus 30 in that prior snapshot: 0 the same number of (0.0%).

Report change
+0
Death-coded reports
+0
Death-coded share
+0.0 pts

This compares reported-event counts in two source snapshots. It does not establish a change in real-world risk, product safety, or disease incidence.

Subscribe to PR-BLOOD VESSEL(S), LESION(S) changes

FDA AER · VeDDRA plate

Code 99591 VOL-TRACE

VOL-TRACE · DEATH-HOT · LOWER-Q · PHOTO-FINISH · SPECIES-DOG · DRUG-LEAD · DESK-WIDE · BOOK-FULL

  • VOL-TRACE 30 reports
  • DEATH-HOT 80.0%
  • LOWER-Q #2006/2481
  • PHOTO-FINISH Abnormal spermatozoa…
  • SPECIES-DOG Dog · 18
  • DRUG-LEAD Dexmedetomidine H… · 4
  • DESK-WIDE 20 breeds
  • BOOK-FULL 8/8 fields

Nearest volume peer: Abnormal spermatozoa NOS (±0 reports)

Upper-third death-coded share drives the outcome stamps on this plate; volume band, corpus rank, and co-report peers follow. Not a clinical diagnosis.

Lower-volume neighbourhood around PR-BLOOD VESSEL, LESION

Lower-third volume poles plus nearest peers, not a full reaction corpus board reprint.

Vomiting · highest174348Abnormal spermatozoa… · near30Atelectasis · near30Bone marrow suppressi… · near30Chronic kidney disease · near30PR-BLOOD VESSEL(S), L… · thi…30Urinary tract neoplas… · low…10
FDA AER report volume · neighbourhood around PR-BLOOD VESSEL(S), LESION(S)

PR-BLOOD VESSEL(S), LESION(S): high death-coded share in the FDA AER plate

Signature read: PR-BLOOD VESSEL(S), LESION(S)'s 80.0% death-coded share is among the highest in the openFDA reaction corpus. Report volume is lower-third scale: 30 named reports in the openFDA extract. Death-coded share is upper-third: 24 of 30 reports (80.0% of named reports). Nearest volume peer: Abnormal spermatozoa NOS (±0 reports). Lead species Dog (18). Lead co-reported drug Dexmedetomidine Hydrochloride (4).

Read these counts as reporting volume, not risk: per our methodology, A high death-coded share in FDA filings does not prove causation; co-reporting is voluntary temporal association only. Browse the full reactions index or the about page for how PlainBreed frames FDA CVM extracts.

Species Most Affected

Dog 18
Cat 7
Cattle 2
Horse 2
Human 1

Breeds Most Affected

Domestic (unspecified) 5
Appaloosa 2
Crossbred Canine/dog 2
Retriever - Labrador 2
Crossbred Bovine/Cattle 1
Siberian Husky 1
Chihuahua 1
Unknown 1
Ridgeback - Rhodesian 1
Greyhound 1

Associated Drugs

Dexmedetomidine Hydrochloride 4
Meloxicam 3
Xylazine 2
Cefovecin Sodium 2
Amoxicillin, Clavulanate 2
Maropitant Citrate 2
Selamectin 1
Ivermectin 1
Enrofloxacin 1
Diclofenac 1
Tiletamine, Zolazepam 1
Deracoxib 1
Moxidectin 1
Carprofen 1
Milbemycin Oxime + Spinosad 1
Maropitant 1
Ceftiofur Crystalline Free Acid 1
Imidacloprid + Moxidectin 1
Glycosaminoglycan Polysulfate 1
Glucosamine/Methylsulfonylmethane/Chondrotin/Avocado-Soybean Unsaponifiables 1

What to do with this reaction

A report does not prove a drug caused the reaction; consult a veterinarian before acting on this data.

Source: FDA Center for Veterinary Medicine openFDA Animal & Veterinary Adverse Events (CVM AER) · 2025

openFDA Animal & Veterinary Adverse Events (FDA CVM) for PR-BLOOD VESSEL(S), LESION(S) (#2006 of 2,481 by report volume); death-coded 80.0%. PlainBreed reaction plate · death-coded share stamp 80.0% · vintage 2025.

Informational only. FDA adverse-event reports are voluntary and do not prove causation; consult a veterinarian before acting on them. Verify with FDA CVM →