Pododermatitis

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VeDDRA Code: 1192

336 adverse event reports referencing this reaction

336
Total Reports
23
Deaths
680.0%
Death Rate

Species Most Affected

Dog 320
Cat 8
Cattle 7
Horse 1

Breeds Most Affected

Retriever - Labrador 36
Boxer (German Boxer) 23
Crossbred Canine/dog 21
Pit Bull 15
Shih Tzu 13
Terrier - Bull - American Pit 12
Beagle 12
Shepherd Dog - German 11
Retriever - Golden 11
Bulldog 10

Associated Drugs

Oclacitinib Maleate 115
Milbemycin Oxime + Spinosad 52
Prednisone 26
Anti-Il31 Mab Mcs Lot #1283563 21
Cefpodoxime Proxetil 20
Afoxolaner 19
Cephalexin 18
Cyclosporine 17
Carprofen 17
Fluralaner Chew Tablets 16
Trilostane 15
Ivermectin + Pyrantel As Pamoate Salt 13
Gabapentin 11
Ketoconazole 10
Bedinvetmab 10
Bordetella Vaccine 9
Sarolaner 9
Fluralaner 13.64% 12-Week Chew 9
Maropitant Citrate 8
Milbemycin Oxime + Praziquantel 8

Data Summary

Metric Value
Total reports referencing reaction 336
Reports with fatal outcome 23
Case-fatality rate (reported events) 680.0%
Species observed 4
Breeds observed 20
Drugs associated with reaction 20

Source: FDA Center for Veterinary Medicine — Adverse Event Reporting (CVM AER); reaction term coded under VeDDRA 1192.

Pododermatitis Reaction Insights

The FDA Center for Veterinary Medicine database currently lists 336 adverse event reports that reference Pododermatitis as a reaction term, including 23 reports with a death outcome — a 680.0% case-fatality figure calculated across only those events where this reaction was coded. The reaction is indexed in the openFDA system under VeDDRA code 1192, the standardized veterinary dictionary used to normalize clinical signs across submitters. Because reports are voluntary and often describe multiple concurrent signs per animal, the volume here reflects reporting intensity rather than true incidence in the broader pet population.

Pododermatitis appears most frequently in reports for Dog (320 reports), Cat (8 reports), Cattle (7 reports) — with Dog dominating at 320 entries. Within those species, the breeds most often named alongside this reaction are Retriever - Labrador (36), Boxer (German Boxer) (23), Crossbred Canine/dog (21). These distributions are influenced both by underlying breed popularity and by how veterinarians and owners code a given clinical sign, so they should be interpreted as a reporting fingerprint rather than a pure susceptibility ranking.

The drugs most commonly co-reported with Pododermatitis are Oclacitinib Maleate (115 reports), Milbemycin Oxime + Spinosad (52 reports), Prednisone (26 reports), Anti-Il31 Mab Mcs Lot #1283563 (21 reports), with Oclacitinib Maleate appearing alongside this reaction in 115 submissions. Co-reporting does not establish that any specific product caused the reaction — FDA CVM data captures temporal association only. The value of these aggregates is in flagging which therapeutic classes appear repeatedly alongside a given clinical sign, so owners and veterinarians can ask targeted questions about medications currently in use.

Source: FDA Center for Veterinary Medicine — Adverse Event Reports FDA Center for Veterinary Medicine — Adverse Event Reports Data reflects voluntary submissions and may not represent actual incidence rates

Related

Data sourced from official AKC, AVMA, ACVO, and breed-club veterinary references. See our methodology for details. Retrieved and formatted by PlainBreed Editorial