Reaction profile

The FDA adverse-event record for pododermatitis

336 FDA adverse-event reports reference pododermatitis (VeDDRA 1192). See the species, breeds, and drugs most associated with it below.

336
reports citing this reaction
6.8%
death-coded share
Dog
most-affected species
Oclacitinib Maleate
most-associated drug
Verify with FDA CVM →
336
Total Reports
23
Deaths
6.8%
Death Rate

Species Most Affected

Dog 320
Cat 8
Cattle 7
Horse 1

Breeds Most Affected

Retriever - Labrador 36
Boxer (German Boxer) 23
Crossbred Canine/dog 21
Pit Bull 15
Shih Tzu 13
Terrier - Bull - American Pit 12
Beagle 12
Shepherd Dog - German 11
Retriever - Golden 11
Bulldog 10

Associated Drugs

Oclacitinib Maleate 115
Milbemycin Oxime + Spinosad 52
Prednisone 26
Anti-Il31 Mab Mcs Lot #1283563 21
Cefpodoxime Proxetil 20
Afoxolaner 19
Cephalexin 18
Cyclosporine 17
Carprofen 17
Fluralaner Chew Tablets 16
Trilostane 15
Ivermectin + Pyrantel As Pamoate Salt 13
Gabapentin 11
Ketoconazole 10
Bedinvetmab 10
Bordetella Vaccine 9
Sarolaner 9
Fluralaner 13.64% 12-Week Chew 9
Maropitant Citrate 8
Milbemycin Oxime + Praziquantel 8

Pododermatitis Reaction Insights

336 reports name Pododermatitis; 23 recorded a death outcome (6.8% of reported events, not a population-level mortality rate). VeDDRA code: 1192.

By species: Dog (320 reports), Cat (8 reports), Cattle (7 reports). By breed: Retriever - Labrador (36), Boxer (German Boxer) (23), Crossbred Canine/dog (21).

Most co-reported drugs: Oclacitinib Maleate (115 reports), Milbemycin Oxime + Spinosad (52 reports), Prednisone (26 reports), Anti-Il31 Mab Mcs Lot #1283563 (21 reports).

Read these counts as reporting volume, not risk: per our methodology, co-reporting reflects temporal association captured in voluntary submissions, not proof that a drug caused this reaction. A widely-prescribed drug will rack up more raw co-reports at an identical true rate than a rarely-used one, so compare within similar-exposure products.

Source: FDA Center for Veterinary Medicine openFDA Animal & Veterinary Adverse Events (CVM AER) · 2025

Every figure on PlainBreed is rendered directly from FDA openFDA adverse event data, no number is typed in by an editor. This page draws directly on FDA openFDA data, no figure is typed in by an editor. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.