Reaction profile

The FDA adverse-event record for warm feeling to the touch

693 FDA reports name warm feeling to the touch, a high-volume reaction in the CVM extract (VeDDRA 2742). Plate stamps and neighbourhood peers follow.

#520 of 2,481
by report volume (all reactions)
693
reports citing this reaction
6.6%
death-coded share
Dog
most-affected species

Release-over-release change

What changed in the latest FDA data snapshot

PlainBreed reconstructed the prior snapshot from dated openFDA partitions through 2025 Q4, then compared it with the 2026-07-27 openFDA export. Warm feeling to the touch has 693 reports now versus 675 in that prior snapshot: 18 more (2.7%).

Report change
+18
Death-coded reports
+1
Death-coded share
−0.0 pts

This compares reported-event counts in two source snapshots. It does not establish a change in real-world risk, product safety, or disease incidence.

Subscribe to Warm feeling to the touch changes

FDA AER · VeDDRA plate

Code 2742 VOL-MID

VOL-MID · DEATH-PAR · UPPER-Q · PHOTO-FINISH · SPECIES-DOG · DRUG-LEAD · DESK-WIDE · BOOK-FULL

  • VOL-MID 693 reports
  • DEATH-PAR 6.6%
  • UPPER-Q #520/2481
  • PHOTO-FINISH Dysphoria
  • SPECIES-DOG Dog · 492
  • DRUG-LEAD Afoxolaner · 70
  • DESK-WIDE 20 breeds
  • BOOK-FULL 8/8 fields

Nearest volume peer: Dysphoria (±0 reports)

Upper-third report volume drives the scale stamps on this plate; death-coded share and co-report peers follow. Not a clinical diagnosis.

High-volume neighbourhood around Warm feeling to the touch

Upper-third volume poles plus nearest peers, not a full reaction corpus board reprint.

Vomiting · highest174348Expired drug administ… · near695Unwell · near694Dysphoria · near693Warm feeling to the t… · thi…693Moist dermatitis · near692Urinary tract neoplas… · low…10
FDA AER report volume · neighbourhood around Warm feeling to the touch

Warm feeling to the touch: low death-coded share in the FDA AER plate

Signature read: 693 reports place Warm feeling to the touch in the upper third of FDA AER volume (#520 of 2,481). Report volume is upper-third scale: 693 named reports in the openFDA extract. Death-coded share is lower-third: 46 of 693 reports (6.6% of named reports). Nearest volume peer: Dysphoria (±0 reports). Lead species Dog (492). Lead co-reported drug Afoxolaner (70).

Read these counts as reporting volume, not risk: per our methodology, Lead co-reported drug Afoxolaner appears in filings alongside this reaction; that is association, not causation. Browse the full reactions index or the about page for how PlainBreed frames FDA CVM extracts.

Species Most Affected

Dog 492
Cat 175
Horse 12
Human 9
Cattle 3
Rabbit 1
Donkey 1

Breeds Most Affected

Domestic Shorthair 104
Chihuahua 50
Retriever - Labrador 45
Crossbred Canine/dog 32
Terrier - Yorkshire 22
Domestic Longhair 22
Retriever - Golden 22
Shepherd Dog - German 16
Shih Tzu 15
Dog (unknown) 14

Associated Drugs

Afoxolaner 70
Nitenpyram 65
Pyrantel Pamoate;Sarolaner 42
Fluralaner 13.64% 12-Week Chew 37
Ivermectin + Pyrantel As Pamoate Salt 35
Bedinvetmab 30
Moxidectin 29
Lotilaner 29
Carprofen 27
Milbemycin Oxime + Spinosad 27
Gabapentin 26
Maropitant Citrate 25
Prednisone 22
Diphenhydramine 21
Buprenorphine 21
Selamectin;Sarolaner 18
Butorphanol 15
Tigilanol Tiglate 15
Fluralaner Spot-On Solution 14
Praziquantel + Pyrantel Pamoate 13

Nationwide reactions with similar profiles

Two openFDA-derived peer sets for Warm feeling to the touch, both floored at ≥50 reports so the neighborhoods stay in the advertised mass (the volume chart above is the unfloored photo-finish strip).

Similar report volume

Nearest other reactions by FDA report count (693 here).

Similar death-coded share

Nearest other reactions by death-coded share (6.6% here), distinct from the volume row.

What to do with this reaction

A report does not prove a drug caused the reaction; consult a veterinarian before acting on this data.

Source: FDA Center for Veterinary Medicine openFDA Animal & Veterinary Adverse Events (CVM AER) · 2025

openFDA Animal & Veterinary Adverse Events (FDA CVM) for Warm feeling to the touch (#520 of 2,481 by report volume); death-coded 6.6%. PlainBreed reaction plate · report volume stamp 693 · vintage 2025.

Informational only. FDA adverse-event reports are voluntary and do not prove causation; consult a veterinarian before acting on them. Verify with FDA CVM →