Reaction profile

The FDA adverse-event record for bone marrow disorder nos

87 FDA adverse-event reports reference bone marrow disorder nos (VeDDRA 1882). See the species, breeds, and drugs most associated with it below.

87
reports citing this reaction
50.6%
death-coded share
Dog
most-affected species
Milbemycin Oxime + Spinosad
most-associated drug
Verify with FDA CVM →
87
Total Reports
44
Deaths
50.6%
Death Rate

Species Most Affected

Dog 71
Cat 15
Ferret 1

Breeds Most Affected

Domestic Shorthair 8
Shepherd Dog - German 6
Retriever - Labrador 6
Crossbred Canine/dog 6
Dog (unknown) 4
Maltese 3
Dachshund (unspecified) 3
Boxer (German Boxer) 3
Terrier - West Highland White 3
Shih Tzu 2

Associated Drugs

Milbemycin Oxime + Spinosad 14
Fluralaner Chew Tablets 14
Oclacitinib Maleate 10
Maropitant Citrate 7
Carprofen 6
Cefovecin 6
Prednisone 6
Trilostane 5
Spinosad 4
Enrofloxacin 4
Doxycycline 4
Estriol Tablets 4
Thiamazole 3
Buprenorphine 3
Afoxolaner 3
Fenbendazol Granules 3
Gabapentin 3
Fluid Therapy 3
Dinotefuran + Pyriproxyfen 2
Moxidectin 2

Bone marrow disorder NOS Reaction Insights

87 reports name Bone marrow disorder NOS; 44 recorded a death outcome (50.6% of reported events, not a population-level mortality rate). VeDDRA code: 1882.

By species: Dog (71 reports), Cat (15 reports), Ferret (1 reports). By breed: Domestic Shorthair (8), Shepherd Dog - German (6), Retriever - Labrador (6).

Most co-reported drugs: Milbemycin Oxime + Spinosad (14 reports), Fluralaner Chew Tablets (14 reports), Oclacitinib Maleate (10 reports), Maropitant Citrate (7 reports).

Read these counts as reporting volume, not risk: per our methodology, co-reporting reflects temporal association captured in voluntary submissions, not proof that a drug caused this reaction. A widely-prescribed drug will rack up more raw co-reports at an identical true rate than a rarely-used one, so compare within similar-exposure products.

Source: FDA Center for Veterinary Medicine openFDA Animal & Veterinary Adverse Events (CVM AER) · 2025

Every figure on PlainBreed is rendered directly from FDA openFDA adverse event data, no number is typed in by an editor. This page draws directly on FDA openFDA data, no figure is typed in by an editor. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.