Reaction profile

The FDA adverse-event record for dermal plaque

77 FDA adverse-event reports reference dermal plaque (VeDDRA 2781). Plate codes and volume neighbourhood below; species, breeds, and drugs follow.

#1517 of 2,481
by report volume (all reactions)
77
reports citing this reaction
1.3%
death-coded share
Dog
most-affected species

Release-over-release change

What changed in the latest FDA data snapshot

PlainBreed reconstructed the prior snapshot from dated openFDA partitions through 2025 Q4, then compared it with the 2026-07-27 openFDA export. Dermal plaque has 77 reports now versus 72 in that prior snapshot: 5 more (6.9%).

Report change
+5
Death-coded reports
+0
Death-coded share
−0.1 pts

This compares reported-event counts in two source snapshots. It does not establish a change in real-world risk, product safety, or disease incidence.

Subscribe to Dermal plaque changes

FDA AER · VeDDRA plate

Code 2781 VOL-LOW

VOL-LOW · DEATH-LOW · MID-PACK · PHOTO-FINISH · SPECIES-DOG · DRUG-LEAD · DESK-WIDE · BOOK-FULL

  • VOL-LOW 77 reports
  • DEATH-LOW 1.3%
  • MID-PACK #1517/2481
  • PHOTO-FINISH Application site twit…
  • SPECIES-DOG Dog · 41
  • DRUG-LEAD Frunevetmab · 26
  • DESK-WIDE 20 breeds
  • BOOK-FULL 8/8 fields

Nearest volume peer: Application site twitching (±0 reports)

Instrument codes from this reaction’s FDA CVM adverse-event extract: volume band, death-coded share, corpus rank, photo-finish peer, lead species, lead drug, breed desk, and book completeness. Not a clinical diagnosis.

Report-volume neighbourhood around Dermal plaque

Highest and lowest poles plus nearest volume peers, not a full 2,500-reaction corpus board reprint.

Vomiting · highest174348Application site twit… · near77Cutaneous oedema · near77Dermal plaque · this reaction77Drug preparation error · near77INEFFECTIVE, APPETITE… · near77Urinary tract neoplas… · low…10
FDA AER report volume · neighbourhood around Dermal plaque

Dermal plaque: low death-coded share in the FDA AER plate

Signature read: 1 death-coded reports is a thin tail count for Dermal plaque in the CVM extract. Report volume sits in the middle third of the reaction corpus. Death-coded share is lower-third: 1 of 77 reports (1.3% of named reports). Nearest volume peer: Application site twitching (±0 reports). Lead species Dog (41). Lead co-reported drug Frunevetmab (26).

Read these counts as reporting volume, not risk: per our methodology, Lead co-reported drug Frunevetmab appears in filings alongside this reaction; that is association, not causation. Browse the full reactions index or the about page for how PlainBreed frames FDA CVM extracts.

Species Most Affected

Dog 41
Cat 36

Breeds Most Affected

Domestic Shorthair 23
Retriever - Labrador 7
Shepherd Dog - German 5
Domestic Longhair 4
Crossbred Canine/dog 3
Boxer (German Boxer) 3
Domestic Mediumhair 3
Terrier - Boston 3
Pug 3
Cat (other) 2

Associated Drugs

Frunevetmab 26
Bedinvetmab 10
Carprofen 9
Maropitant Citrate 8
Cefovecin 8
Oclacitinib Maleate 8
Trilostane 7
Prednisone 5
Selamectin;Sarolaner 4
Anti-Il31 Mab Mcs Lot #1283563 4
Cyclosporine 4
Gabapentin 3
Iv Fluids 3
Dexamethasone 3
Afoxolaner 3
Probiotic 2
Trazodone 2
Tigilanol Tiglate 2
Methylprednisolone Acetate 2
Prednisolone 2

Nationwide reactions with similar profiles

Two openFDA-derived peer sets for Dermal plaque, both floored at ≥50 reports so the neighborhoods stay in the advertised mass (the volume chart above is the unfloored photo-finish strip).

Similar death-coded share

Nearest other reactions by death-coded share (1.3% here), distinct from the volume row.

What to do with this reaction

A report does not prove a drug caused the reaction; consult a veterinarian before acting on this data.

Source: FDA Center for Veterinary Medicine openFDA Animal & Veterinary Adverse Events (CVM AER) · 2025

openFDA Animal & Veterinary Adverse Events (FDA CVM) for Dermal plaque (#1517 of 2,481 by report volume); death-coded 1.3%. PlainBreed reaction plate · death-coded report count stamp 1 · vintage 2025.

Informational only. FDA adverse-event reports are voluntary and do not prove causation; consult a veterinarian before acting on them. Verify with FDA CVM →