Reaction profile

The FDA adverse-event record for reduced conception rate

107 FDA adverse-event reports reference reduced conception rate (VeDDRA 1163). Plate codes and volume neighbourhood below; species, breeds, and drugs follow.

#1358 of 2,481
by report volume (all reactions)
107
reports citing this reaction
3.7%
death-coded share
Cattle
most-affected species

Release-over-release change

What changed in the latest FDA data snapshot

PlainBreed reconstructed the prior snapshot from dated openFDA partitions through 2025 Q4, then compared it with the 2026-07-27 openFDA export. Reduced conception rate has 107 reports now versus 107 in that prior snapshot: 0 the same number of (0.0%).

Report change
+0
Death-coded reports
+0
Death-coded share
+0.0 pts

This compares reported-event counts in two source snapshots. It does not establish a change in real-world risk, product safety, or disease incidence.

Subscribe to Reduced conception rate changes

FDA AER · VeDDRA plate

Code 1163 VOL-LOW

VOL-LOW · DEATH-LOW · MID-PACK · PHOTO-FINISH · SPECIES-CATTLE · DRUG-LEAD · DESK-WIDE · BOOK-FULL

  • VOL-LOW 107 reports
  • DEATH-LOW 3.7%
  • MID-PACK #1358/2481
  • PHOTO-FINISH Gel/Paste, Abnormal
  • SPECIES-CATTLE Cattle · 57
  • DRUG-LEAD Sometribove · 17
  • DESK-WIDE 20 breeds
  • BOOK-FULL 8/8 fields

Nearest volume peer: Gel/Paste, Abnormal (±0 reports)

Instrument codes from this reaction’s FDA CVM adverse-event extract: volume band, death-coded share, corpus rank, photo-finish peer, lead species, lead drug, breed desk, and book completeness. Not a clinical diagnosis.

Report-volume neighbourhood around Reduced conception rate

Highest and lowest poles plus nearest volume peers, not a full 2,500-reaction corpus board reprint.

Vomiting · highest174348Acid-base disorder · near108Gel/Paste, Abnormal · near107Injection site crust · near107Lack of efficacy, med… · near107Reduced conception ra… · thi…107Urinary tract neoplas… · low…10
FDA AER report volume · neighbourhood around Reduced conception rate

Reduced conception rate: low death-coded share in the FDA AER plate

Signature read: Reduced conception rate's 3.7% death-coded share is among the lowest in the openFDA reaction corpus. Report volume sits in the middle third of the reaction corpus. Death-coded share is lower-third: 4 of 107 reports (3.7% of named reports). Nearest volume peer: Gel/Paste, Abnormal (±0 reports). Lead species Cattle (57). Lead co-reported drug Sometribove (17).

Read these counts as reporting volume, not risk: per our methodology, Lead co-reported drug Sometribove appears in filings alongside this reaction; that is association, not causation. Browse the full reactions index or the about page for how PlainBreed frames FDA CVM extracts.

Species Most Affected

Cattle 57
Dog 39
Pig 4
Sheep 4
Horse 1
Deer 1
Goat 1

Breeds Most Affected

Holstein-Friesian also known as Holstein 24
Retriever - Golden 13
Mixed (Cattle) 9
Aberdeen Angus 7
Cattle (other) 6
Jersey 5
Terrier - Scottish 4
Dog (unknown) 4
Terrier - Silky 2
Pig (unknown) 2

Associated Drugs

Sometribove 17
Monensin Sodium 16
Spinosad 15
Imidacloprid + Moxidectin 11
Milbemycin Oxime + Spinosad 8
Progesterone 7
Albendazole 7
Sometribove Zinc Suspension 6
Eprinomectin 5
Dinoprost Tromethamine 4
Pregnyl/Gestyl 200/400 4
Leptospira Canicola L-15 Strain C-51;Leptospira Grippotyphosa 1550 Lot 10005 Str 4
Melengestrol Acetate 3
Gonadorelin Hydrochloride 3
Heartworm Prevention (Unknown) 2
Bovine Respiratory Syncytial Virus, 597-10 10Th Psg Strain 375; Bovine Viral Dia 2
Doramectin 2
Nitenpyram 2
Fluralaner Chew Tablets 2
Testosterone Propionate;Estradiol Benzoate 2

Nationwide reactions with similar profiles

Two openFDA-derived peer sets for Reduced conception rate, both floored at ≥50 reports so the neighborhoods stay in the advertised mass (the volume chart above is the unfloored photo-finish strip).

Similar death-coded share

Nearest other reactions by death-coded share (3.7% here), distinct from the volume row.

What to do with this reaction

A report does not prove a drug caused the reaction; consult a veterinarian before acting on this data.

Source: FDA Center for Veterinary Medicine openFDA Animal & Veterinary Adverse Events (CVM AER) · 2025

openFDA Animal & Veterinary Adverse Events (FDA CVM) for Reduced conception rate (#1358 of 2,481 by report volume); death-coded 3.7%. PlainBreed reaction plate · death-coded share stamp 3.7% · vintage 2025.

Informational only. FDA adverse-event reports are voluntary and do not prove causation; consult a veterinarian before acting on them. Verify with FDA CVM →