Reaction profile

The FDA adverse-event record for necrotising steatitis

18 FDA adverse-event reports reference necrotising steatitis (VeDDRA 1037). See the species, breeds, and drugs most associated with it below.

18
reports citing this reaction
22.2%
death-coded share
Dog
most-affected species
Device: Suture
most-associated drug
Verify with FDA CVM →
18
Total Reports
4
Deaths
22.2%
Death Rate

Species Most Affected

Dog 13
Cat 5

Breeds Most Affected

Retriever - Labrador 5
Cat (unknown) 4
Retriever (unspecified) 1
Terrier (unspecified) 1
Retriever - Golden 1
Saint Bernard Dog 1
Rottweiler 1
Domestic Shorthair 1
Mixed (Dog) 1
Spitz - German Pomeranian 1

Associated Drugs

Device: Suture 4
Prednisone 3
Melarsomine Dihydrochloride 3
Tramadol 2
Milbemycin Oxime + Spinosad 2
Deracoxib 2
Melarsomine Dihydrocloride Injectable 25Mg/Ml 1
Moxidectin 1
Triamcinolone Acetonide 1
Cephalexin 1
Desoxycorticosterone Pivalate 1
Levothyroxine 1
Glucosamine 1
Unknown Antibiotic 1
Acepromazine 1
Butorphanol Tartrate 1
Cefazolin 1
Isoflurane 1
Amoxicillin 1
Polysulfated Glycosaminoglycan 1

Necrotising steatitis Reaction Insights

18 reports name Necrotising steatitis; 4 recorded a death outcome (22.2% of reported events, not a population-level mortality rate). VeDDRA code: 1037.

By species: Dog (13 reports), Cat (5 reports). By breed: Retriever - Labrador (5), Cat (unknown) (4), Retriever (unspecified) (1).

Most co-reported drugs: Device: Suture (4 reports), Prednisone (3 reports), Melarsomine Dihydrochloride (3 reports), Tramadol (2 reports).

Read these counts as reporting volume, not risk: per our methodology, co-reporting reflects temporal association captured in voluntary submissions, not proof that a drug caused this reaction. A widely-prescribed drug will rack up more raw co-reports at an identical true rate than a rarely-used one, so compare within similar-exposure products.

Source: FDA Center for Veterinary Medicine openFDA Animal & Veterinary Adverse Events (CVM AER) · 2025

Every figure on PlainBreed is rendered directly from FDA openFDA adverse event data, no number is typed in by an editor. This page draws directly on FDA openFDA data, no figure is typed in by an editor. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.