Reaction profile

The FDA adverse-event record for necrotising steatitis

18 FDA reports name necrotising steatitis, a lower-volume reaction in the CVM extract (VeDDRA 1037). Plate stamps and neighbourhood peers follow.

#2219 of 2,481
by report volume (all reactions)
18
reports citing this reaction
22.2%
death-coded share
Dog
most-affected species

Release-over-release change

What changed in the latest FDA data snapshot

PlainBreed reconstructed the prior snapshot from dated openFDA partitions through 2025 Q4, then compared it with the 2026-07-27 openFDA export. Necrotising steatitis has 18 reports now versus 18 in that prior snapshot: 0 the same number of (0.0%).

Report change
+0
Death-coded reports
+0
Death-coded share
+0.0 pts

This compares reported-event counts in two source snapshots. It does not establish a change in real-world risk, product safety, or disease incidence.

Subscribe to Necrotising steatitis changes

FDA AER · VeDDRA plate

Code 1037 VOL-TRACE

VOL-TRACE · DEATH-HOT · LOWER-Q · PHOTO-FINISH · SPECIES-DOG · DRUG-LEAD · DESK-WIDE · BOOK-FULL

  • VOL-TRACE 18 reports
  • DEATH-HOT 22.2%
  • LOWER-Q #2219/2481
  • PHOTO-FINISH ALBUMIN/GLOBULIN RATI…
  • SPECIES-DOG Dog · 13
  • DRUG-LEAD Device: Suture · 4
  • DESK-WIDE 11 breeds
  • BOOK-FULL 8/8 fields

Nearest volume peer: ALBUMIN/GLOBULIN RATIO HI, BLD (±0 reports)

Instrument codes from this reaction’s FDA CVM adverse-event extract: volume band, death-coded share, corpus rank, photo-finish peer, lead species, lead drug, breed desk, and book completeness. Not a clinical diagnosis.

Lower-volume neighbourhood around Necrotising steatitis

Lower-third volume poles plus nearest peers, not a full reaction corpus board reprint.

Vomiting · highest174348ALBUMIN/GLOBULIN RATI… · near18Application site skin… · near18Bone marrow hypoplasia · near18Cognitive disturbance · near18Necrotising steatitis · this…18Urinary tract neoplas… · low…10
FDA AER report volume · neighbourhood around Necrotising steatitis

What the FDA AER plate says about Necrotising steatitis

Signature read: 18 reports place Necrotising steatitis in the lower third of FDA AER volume (#2219 of 2,481). Report volume is lower-third scale: 18 named reports in the openFDA extract. 4 of 18 reports were death-coded (22.2% of named reports, not a population mortality rate). Nearest volume peer: ALBUMIN/GLOBULIN RATIO HI, BLD (±0 reports). Lead species Dog (13). Lead co-reported drug Device: Suture (4).

Read these counts as reporting volume, not risk: per our methodology, Lead co-reported drug Device: Suture appears in filings alongside this reaction; that is association, not causation. Browse the full reactions index or the about page for how PlainBreed frames FDA CVM extracts.

Species Most Affected

Dog 13
Cat 5

Breeds Most Affected

Retriever - Labrador 5
Cat (unknown) 4
Retriever (unspecified) 1
Terrier (unspecified) 1
Retriever - Golden 1
Saint Bernard Dog 1
Rottweiler 1
Domestic Shorthair 1
Mixed (Dog) 1
Spitz - German Pomeranian 1

Associated Drugs

Device: Suture 4
Prednisone 3
Melarsomine Dihydrochloride 3
Tramadol 2
Milbemycin Oxime + Spinosad 2
Deracoxib 2
Melarsomine Dihydrocloride Injectable 25Mg/Ml 1
Moxidectin 1
Triamcinolone Acetonide 1
Cephalexin 1
Desoxycorticosterone Pivalate 1
Levothyroxine 1
Glucosamine 1
Unknown Antibiotic 1
Acepromazine 1
Butorphanol Tartrate 1
Cefazolin 1
Isoflurane 1
Amoxicillin 1
Polysulfated Glycosaminoglycan 1

What to do with this reaction

A report does not prove a drug caused the reaction; consult a veterinarian before acting on this data.

Source: FDA Center for Veterinary Medicine openFDA Animal & Veterinary Adverse Events (CVM AER) · 2025

openFDA Animal & Veterinary Adverse Events (FDA CVM) for Necrotising steatitis (#2219 of 2,481 by report volume); death-coded 22.2%. PlainBreed reaction plate · report volume stamp 18 · vintage 2025.

Informational only. FDA adverse-event reports are voluntary and do not prove causation; consult a veterinarian before acting on them. Verify with FDA CVM →