Cyst NOS

Verify with FDA CVM →

VeDDRA Code: 2884

102 adverse event reports referencing this reaction

102
Total Reports
12
Deaths
1180.0%
Death Rate

Species Most Affected

Dog 89
Cat 12
Horse 1

Breeds Most Affected

Retriever - Labrador 16
Retriever - Golden 8
Domestic Shorthair 7
Shepherd Dog - German 6
Dog (unknown) 6
Crossbred Canine/dog 6
Pit Bull 4
Boxer (German Boxer) 3
Spitz - American Eskimo Dog 3
Terrier - Bull - American Pit 3

Associated Drugs

Oclacitinib Maleate 30
Bedinvetmab 14
Milbemycin Oxime + Praziquantel 9
Gabapentin 8
Lotilaner 7
Anti-Il31 Mab Mcs Lot #1283563 7
Carprofen 6
Grapiprant 5
Maropitant Citrate 5
Frunevetmab 5
Bexagliflozin 5
Ilunocitinib 5
Rabies Vaccine 4
Melarsomine Dihydrochloride 4
Pyrantel Pamoate;Sarolaner 4
Butorphanol 4
Fluralaner 13.64% 12-Week Chew 4
Doxycycline 3
Tigilanol Tiglate 3
Imidacloprid + Moxidectin 3

Data Summary

Metric Value
Total reports referencing reaction 102
Reports with fatal outcome 12
Case-fatality rate (reported events) 1180.0%
Species observed 3
Breeds observed 20
Drugs associated with reaction 20

Source: FDA Center for Veterinary Medicine — Adverse Event Reporting (CVM AER); reaction term coded under VeDDRA 2884.

Cyst NOS Reaction Insights

The FDA Center for Veterinary Medicine database currently lists 102 adverse event reports that reference Cyst NOS as a reaction term, including 12 reports with a death outcome — a 1180.0% case-fatality figure calculated across only those events where this reaction was coded. The reaction is indexed in the openFDA system under VeDDRA code 2884, the standardized veterinary dictionary used to normalize clinical signs across submitters. Because reports are voluntary and often describe multiple concurrent signs per animal, the volume here reflects reporting intensity rather than true incidence in the broader pet population.

Cyst NOS appears most frequently in reports for Dog (89 reports), Cat (12 reports), Horse (1 reports) — with Dog dominating at 89 entries. Within those species, the breeds most often named alongside this reaction are Retriever - Labrador (16), Retriever - Golden (8), Domestic Shorthair (7). These distributions are influenced both by underlying breed popularity and by how veterinarians and owners code a given clinical sign, so they should be interpreted as a reporting fingerprint rather than a pure susceptibility ranking.

The drugs most commonly co-reported with Cyst NOS are Oclacitinib Maleate (30 reports), Bedinvetmab (14 reports), Milbemycin Oxime + Praziquantel (9 reports), Gabapentin (8 reports), with Oclacitinib Maleate appearing alongside this reaction in 30 submissions. Co-reporting does not establish that any specific product caused the reaction — FDA CVM data captures temporal association only. The value of these aggregates is in flagging which therapeutic classes appear repeatedly alongside a given clinical sign, so owners and veterinarians can ask targeted questions about medications currently in use.

Source: FDA Center for Veterinary Medicine — Adverse Event Reports FDA Center for Veterinary Medicine — Adverse Event Reports Data reflects voluntary submissions and may not represent actual incidence rates

Related

Data sourced from official AKC, AVMA, ACVO, and breed-club veterinary references. See our methodology for details. Retrieved and formatted by PlainBreed Editorial