Reaction profile

The FDA adverse-event record for bone marrow hypoplasia

17 FDA adverse-event reports reference bone marrow hypoplasia (VeDDRA 2385). See the species, breeds, and drugs most associated with it below.

17
reports citing this reaction
35.3%
death-coded share
Dog
most-affected species
Oclacitinib Maleate
most-associated drug
Verify with FDA CVM →
17
Total Reports
6
Deaths
35.3%
Death Rate

Species Most Affected

Dog 16
Cat 1

Breeds Most Affected

Retriever - Labrador 3
Chihuahua 1
Bulldog 1
Pit Bull 1
Berger Picard or Sheepdog - Picardy 1
Siamese 1
Shiba Inu 1
Terrier - Bull - American Pit 1
Shepherd Dog - German 1
Bichon Frise 1

Associated Drugs

Oclacitinib Maleate 5
Maropitant Citrate 3
Fenbendazol Granules 2
Cephalexin 2
Doxycycline 2
Fluralaner Chew Tablets 2
Enrofloxacin 2
Clindamycin 2
Omeprazole 2
Metronidazole 2
Prednisone 1
Fenbendazol Suspension 1
Sulfadimethoxine 1
Leptospira Canicola L-15 Strain C-51; Leptospira Grippotyphosa 1550 Lot 10005 St 1
Fenbendazole 1
Dexamethasone + Neomycin Sulfate + Thiabendazole 1
Purevax Feline Rabies - 1901.R1 1
Febantel + Praziquantel + Pyrantel Pamoate 1
Lactacted Ringers Solution 1
Potassium Chloride 1

Bone marrow hypoplasia Reaction Insights

17 reports name Bone marrow hypoplasia; 6 recorded a death outcome (35.3% of reported events, not a population-level mortality rate). VeDDRA code: 2385.

By species: Dog (16 reports), Cat (1 reports). By breed: Retriever - Labrador (3), Chihuahua (1), Bulldog (1).

Most co-reported drugs: Oclacitinib Maleate (5 reports), Maropitant Citrate (3 reports), Fenbendazol Granules (2 reports), Cephalexin (2 reports).

Read these counts as reporting volume, not risk: per our methodology, co-reporting reflects temporal association captured in voluntary submissions, not proof that a drug caused this reaction. A widely-prescribed drug will rack up more raw co-reports at an identical true rate than a rarely-used one, so compare within similar-exposure products.

Source: FDA Center for Veterinary Medicine openFDA Animal & Veterinary Adverse Events (CVM AER) · 2025

Every figure on PlainBreed is rendered directly from FDA openFDA adverse event data, no number is typed in by an editor. This page draws directly on FDA openFDA data, no figure is typed in by an editor. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.