Blood in faeces NOS

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VeDDRA Code: 1081

308 adverse event reports referencing this reaction

308
Total Reports
35
Deaths
1140.0%
Death Rate

Species Most Affected

Dog 287
Cat 18
Cattle 2
Mouse 1

Breeds Most Affected

Crossbred Canine/dog 26
Retriever - Labrador 19
Chihuahua 14
Dog (unknown) 14
Shepherd Dog - Australian 12
Retriever - Golden 11
Domestic Shorthair 10
Beagle 10
Terrier - Yorkshire 9
Maltese 9

Associated Drugs

Pyrantel Pamoate;Sarolaner 35
Fluralaner 13.64% 12-Week Chew 26
Ivermectin + Pyrantel As Pamoate Salt 26
Afoxolaner 26
Moxidectin 25
Milbemycin Oxime + Praziquantel 23
Carprofen 22
Maropitant Citrate 15
Trilostane 14
Meloxicam 11
Lotilaner 10
Prednisone 9
Grapiprant 9
Pimobendan 9
Oclacitinib Maleate 8
Milbemycin Oxime + Spinosad 8
Leptospira Canicola L-15 Strain C-51;Leptospira Grippotyphosa 1550 Lot 10005 Str 7
Ivermectin 7
Melarsomine Dihydrochloride 7
Sarolaner 6

Data Summary

Metric Value
Total reports referencing reaction 308
Reports with fatal outcome 35
Case-fatality rate (reported events) 1140.0%
Species observed 4
Breeds observed 20
Drugs associated with reaction 20

Source: FDA Center for Veterinary Medicine — Adverse Event Reporting (CVM AER); reaction term coded under VeDDRA 1081.

Blood in faeces NOS Reaction Insights

The FDA Center for Veterinary Medicine database currently lists 308 adverse event reports that reference Blood in faeces NOS as a reaction term, including 35 reports with a death outcome — a 1140.0% case-fatality figure calculated across only those events where this reaction was coded. The reaction is indexed in the openFDA system under VeDDRA code 1081, the standardized veterinary dictionary used to normalize clinical signs across submitters. Because reports are voluntary and often describe multiple concurrent signs per animal, the volume here reflects reporting intensity rather than true incidence in the broader pet population.

Blood in faeces NOS appears most frequently in reports for Dog (287 reports), Cat (18 reports), Cattle (2 reports) — with Dog dominating at 287 entries. Within those species, the breeds most often named alongside this reaction are Crossbred Canine/dog (26), Retriever - Labrador (19), Chihuahua (14). These distributions are influenced both by underlying breed popularity and by how veterinarians and owners code a given clinical sign, so they should be interpreted as a reporting fingerprint rather than a pure susceptibility ranking.

The drugs most commonly co-reported with Blood in faeces NOS are Pyrantel Pamoate;Sarolaner (35 reports), Fluralaner 13.64% 12-Week Chew (26 reports), Ivermectin + Pyrantel As Pamoate Salt (26 reports), Afoxolaner (26 reports), with Pyrantel Pamoate;Sarolaner appearing alongside this reaction in 35 submissions. Co-reporting does not establish that any specific product caused the reaction — FDA CVM data captures temporal association only. The value of these aggregates is in flagging which therapeutic classes appear repeatedly alongside a given clinical sign, so owners and veterinarians can ask targeted questions about medications currently in use.

Source: FDA Center for Veterinary Medicine — Adverse Event Reports FDA Center for Veterinary Medicine — Adverse Event Reports Data reflects voluntary submissions and may not represent actual incidence rates

Related

Data sourced from official AKC, AVMA, ACVO, and breed-club veterinary references. See our methodology for details. Retrieved and formatted by PlainBreed Editorial