Reaction profile

The FDA adverse-event record for blood in faeces nos

308 FDA adverse-event reports reference blood in faeces nos (VeDDRA 1081). See the species, breeds, and drugs most associated with it below.

308
reports citing this reaction
11.4%
death-coded share
Dog
most-affected species
Pyrantel Pamoate;Sarolaner
most-associated drug
Verify with FDA CVM →
308
Total Reports
35
Deaths
11.4%
Death Rate

Species Most Affected

Dog 287
Cat 18
Cattle 2
Mouse 1

Breeds Most Affected

Crossbred Canine/dog 26
Retriever - Labrador 19
Chihuahua 14
Dog (unknown) 14
Shepherd Dog - Australian 12
Retriever - Golden 11
Domestic Shorthair 10
Beagle 10
Terrier - Yorkshire 9
Maltese 9

Associated Drugs

Pyrantel Pamoate;Sarolaner 35
Fluralaner 13.64% 12-Week Chew 26
Ivermectin + Pyrantel As Pamoate Salt 26
Afoxolaner 26
Moxidectin 25
Milbemycin Oxime + Praziquantel 23
Carprofen 22
Maropitant Citrate 15
Trilostane 14
Meloxicam 11
Lotilaner 10
Prednisone 9
Grapiprant 9
Pimobendan 9
Oclacitinib Maleate 8
Milbemycin Oxime + Spinosad 8
Leptospira Canicola L-15 Strain C-51;Leptospira Grippotyphosa 1550 Lot 10005 Str 7
Ivermectin 7
Melarsomine Dihydrochloride 7
Sarolaner 6

Blood in faeces NOS Reaction Insights

308 reports name Blood in faeces NOS; 35 recorded a death outcome (11.4% of reported events, not a population-level mortality rate). VeDDRA code: 1081.

By species: Dog (287 reports), Cat (18 reports), Cattle (2 reports). By breed: Crossbred Canine/dog (26), Retriever - Labrador (19), Chihuahua (14).

Most co-reported drugs: Pyrantel Pamoate;Sarolaner (35 reports), Fluralaner 13.64% 12-Week Chew (26 reports), Ivermectin + Pyrantel As Pamoate Salt (26 reports), Afoxolaner (26 reports).

Read these counts as reporting volume, not risk: per our methodology, co-reporting reflects temporal association captured in voluntary submissions, not proof that a drug caused this reaction. A widely-prescribed drug will rack up more raw co-reports at an identical true rate than a rarely-used one, so compare within similar-exposure products.

Source: FDA Center for Veterinary Medicine openFDA Animal & Veterinary Adverse Events (CVM AER) · 2025

Every figure on PlainBreed is rendered directly from FDA openFDA adverse event data, no number is typed in by an editor. This page draws directly on FDA openFDA data, no figure is typed in by an editor. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.