Reaction profile

The FDA adverse-event record for coughing up blood

185 FDA adverse-event reports reference coughing up blood (VeDDRA 1970). Plate codes and volume neighbourhood below; species, breeds, and drugs follow.

#1076 of 2,481
by report volume (all reactions)
185
reports citing this reaction
34.1%
death-coded share
Dog
most-affected species

Release-over-release change

What changed in the latest FDA data snapshot

PlainBreed reconstructed the prior snapshot from dated openFDA partitions through 2025 Q4, then compared it with the 2026-07-27 openFDA export. Coughing up blood has 185 reports now versus 180 in that prior snapshot: 5 more (2.8%).

Report change
+5
Death-coded reports
+3
Death-coded share
+0.7 pts

This compares reported-event counts in two source snapshots. It does not establish a change in real-world risk, product safety, or disease incidence.

Subscribe to Coughing up blood changes

FDA AER · VeDDRA plate

Code 1970 VOL-LOW

VOL-LOW · DEATH-HOT · MID-PACK · PHOTO-FINISH · SPECIES-DOG · DRUG-LEAD · DESK-WIDE · BOOK-FULL

  • VOL-LOW 185 reports
  • DEATH-HOT 34.1%
  • MID-PACK #1076/2481
  • PHOTO-FINISH Epidermal collarette
  • SPECIES-DOG Dog · 176
  • DRUG-LEAD Melarsomine Dihyd… · 26
  • DESK-WIDE 20 breeds
  • BOOK-FULL 8/8 fields

Nearest volume peer: Epidermal collarette (±0 reports)

Upper-third death-coded share drives the outcome stamps on this plate; volume band, corpus rank, and co-report peers follow. Not a clinical diagnosis.

Report-volume neighbourhood around Coughing up blood

Highest and lowest poles plus nearest volume peers, not a full 2,500-reaction corpus board reprint.

Vomiting · highest174348Coughing up blood · this rea…185Epidermal collarette · near185Peripheral nervous sy… · near185Thyroid gland disorde… · near185BANDS(NEUTROPHILS) HI… · near184Urinary tract neoplas… · low…10
FDA AER report volume · neighbourhood around Coughing up blood

Coughing up blood: high death-coded share in the FDA AER plate

Signature read: Coughing up blood's 34.1% death-coded share is among the highest in the openFDA reaction corpus. Report volume sits in the middle third of the reaction corpus. Death-coded share is upper-third: 63 of 185 reports (34.1% of named reports). Nearest volume peer: Epidermal collarette (±0 reports). Lead species Dog (176). Lead co-reported drug Melarsomine Dihydrochloride (26).

Read these counts as reporting volume, not risk: per our methodology, A high death-coded share in FDA filings does not prove causation; co-reporting is voluntary temporal association only. Browse the full reactions index or the about page for how PlainBreed frames FDA CVM extracts.

Species Most Affected

Dog 176
Cat 5
Other Equids 2
Cattle 1
Human 1

Breeds Most Affected

Retriever - Labrador 20
Pit Bull 13
Shih Tzu 11
Chihuahua 11
Boxer (German Boxer) 8
Dog (unknown) 6
Crossbred Canine/dog 6
Terrier - Bull - American Pit 6
Retriever - Golden 5
Mixed (Dog) 4

Associated Drugs

Melarsomine Dihydrochloride 26
Milbemycin Oxime + Spinosad 21
Doxycycline 17
Maropitant Citrate 16
Carprofen 14
Ivermectin + Pyrantel As Pamoate Salt 13
Moxidectin 13
Melarsomine Dihydrochloride Injection 12
Prednisone 12
Furosemide 8
Spinosad 8
Oclacitinib Maleate 8
Leptospira Canicola L-15 Strain C-51;Leptospira Grippotyphosa 1550 Lot 10005 Str 7
Melarsomine Dihydrocloride Injectable 25Mg/Ml 6
Butorphanol 6
Milbemycin Oxime 6
Dexamethasone 6
Enrofloxacin 5
Pimobendan 5
Afoxolaner 5

Nationwide reactions with similar profiles

Two openFDA-derived peer sets for Coughing up blood, both floored at ≥50 reports so the neighborhoods stay in the advertised mass (the volume chart above is the unfloored photo-finish strip).

What to do with this reaction

A report does not prove a drug caused the reaction; consult a veterinarian before acting on this data.

Source: FDA Center for Veterinary Medicine openFDA Animal & Veterinary Adverse Events (CVM AER) · 2025

openFDA Animal & Veterinary Adverse Events (FDA CVM) for Coughing up blood (#1076 of 2,481 by report volume); death-coded 34.1%. PlainBreed reaction plate · death-coded share stamp 34.1% · vintage 2025.

Informational only. FDA adverse-event reports are voluntary and do not prove causation; consult a veterinarian before acting on them. Verify with FDA CVM →