Reaction profile

The FDA adverse-event record for intestinal disorder nos

831 FDA adverse-event reports reference intestinal disorder nos (VeDDRA 2440). See the species, breeds, and drugs most associated with it below.

831
reports citing this reaction
26.7%
death-coded share
Dog
most-affected species
Maropitant Citrate
most-associated drug
Verify with FDA CVM →
831
Total Reports
222
Deaths
26.7%
Death Rate

Species Most Affected

Dog 630
Cat 145
Horse 23
Cattle 13
Human 7
Pig 4
Chicken 4
Donkey 2
Goat 1
Turkey 1

Breeds Most Affected

Retriever - Labrador 69
Domestic Shorthair 68
Dog (unknown) 42
Crossbred Canine/dog 41
Terrier - Yorkshire 28
Chihuahua 22
Shih Tzu 19
Domestic Longhair 19
Shepherd Dog - German 19
Shepherd Dog - Australian 17

Associated Drugs

Maropitant Citrate 88
Fluralaner Chew Tablets 69
Carprofen 57
Ivermectin + Pyrantel As Pamoate Salt 55
Oclacitinib Maleate 53
Trilostane 45
Milbemycin Oxime + Praziquantel 44
Gabapentin 42
Fluralaner 13.64% 12-Week Chew 40
Bedinvetmab 40
Afoxolaner 34
Metronidazole 32
Milbemycin Oxime + Spinosad 29
Buprenorphine 28
Pyrantel Pamoate;Sarolaner 28
Enrofloxacin 26
Prednisone 23
Grapiprant 21
Famotidine 19
Cefovecin 18

Intestinal disorder NOS Reaction Insights

831 reports name Intestinal disorder NOS; 222 recorded a death outcome (26.7% of reported events, not a population-level mortality rate). VeDDRA code: 2440.

By species: Dog (630 reports), Cat (145 reports), Horse (23 reports). By breed: Retriever - Labrador (69), Domestic Shorthair (68), Dog (unknown) (42).

Most co-reported drugs: Maropitant Citrate (88 reports), Fluralaner Chew Tablets (69 reports), Carprofen (57 reports), Ivermectin + Pyrantel As Pamoate Salt (55 reports).

Read these counts as reporting volume, not risk: per our methodology, co-reporting reflects temporal association captured in voluntary submissions, not proof that a drug caused this reaction. A widely-prescribed drug will rack up more raw co-reports at an identical true rate than a rarely-used one, so compare within similar-exposure products.

Source: FDA Center for Veterinary Medicine openFDA Animal & Veterinary Adverse Events (CVM AER) · 2025

Every figure on PlainBreed is rendered directly from FDA openFDA adverse event data, no number is typed in by an editor. This page draws directly on FDA openFDA data, no figure is typed in by an editor. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.