Reaction profile

The FDA adverse-event record for injection site serous discharge

139 FDA adverse-event reports reference injection site serous discharge (VeDDRA 105). Plate codes and volume neighbourhood below; species, breeds, and drugs follow.

#1229 of 2,481
by report volume (all reactions)
139
reports citing this reaction
7.9%
death-coded share
Dog
most-affected species

Release-over-release change

What changed in the latest FDA data snapshot

PlainBreed reconstructed the prior snapshot from dated openFDA partitions through 2025 Q4, then compared it with the 2026-07-27 openFDA export. Injection site serous discharge has 139 reports now versus 138 in that prior snapshot: 1 more (0.7%).

Report change
+1
Death-coded reports
+0
Death-coded share
−0.1 pts

This compares reported-event counts in two source snapshots. It does not establish a change in real-world risk, product safety, or disease incidence.

Subscribe to Injection site serous discharge changes

FDA AER · VeDDRA plate

Code 105 VOL-LOW

VOL-LOW · DEATH-PAR · MID-PACK · PHOTO-FINISH · SPECIES-DOG · DRUG-LEAD · DESK-WIDE · BOOK-FULL

  • VOL-LOW 139 reports
  • DEATH-PAR 7.9%
  • MID-PACK #1229/2481
  • PHOTO-FINISH Haemolytic anaemia
  • SPECIES-DOG Dog · 118
  • DRUG-LEAD Tigilanol Tiglate · 60
  • DESK-WIDE 20 breeds
  • BOOK-FULL 8/8 fields

Nearest volume peer: Haemolytic anaemia (±0 reports)

Instrument codes from this reaction’s FDA CVM adverse-event extract: volume band, death-coded share, corpus rank, photo-finish peer, lead species, lead drug, breed desk, and book completeness. Not a clinical diagnosis.

Report-volume neighbourhood around Injection site serous discharge

Highest and lowest poles plus nearest volume peers, not a full 2,500-reaction corpus board reprint.

Vomiting · highest174348Dehiscence, medical d… · near140Haemolytic anaemia · near139INEFFECTIVE, ESTRUS S… · near139Injection site serous… · thi…139Ventricular arrhythmia · near139Urinary tract neoplas… · low…10
FDA AER report volume · neighbourhood around Injection site serous discharge

Injection site serous discharge: low death-coded share in the FDA AER plate

Signature read: death-coded share at 7.9% is the most distinctive outcome stamp on Injection site serous discharge. Report volume sits in the middle third of the reaction corpus. Death-coded share is lower-third: 11 of 139 reports (7.9% of named reports). Nearest volume peer: Haemolytic anaemia (±0 reports). Lead species Dog (118). Lead co-reported drug Tigilanol Tiglate (60).

Read these counts as reporting volume, not risk: per our methodology, Lead co-reported drug Tigilanol Tiglate appears in filings alongside this reaction; that is association, not causation. Browse the full reactions index or the about page for how PlainBreed frames FDA CVM extracts.

Species Most Affected

Dog 118
Horse 9
Cat 8
Cattle 2
Goat 1
Pig 1

Breeds Most Affected

Retriever - Labrador 12
Pit Bull 11
Domestic Shorthair 8
Boxer (German Boxer) 8
Dog (unknown) 7
Beagle 5
Quarter Horse 5
Terrier - Bull - Staffordshire 5
Dachshund (unspecified) 4
Shepherd Dog - German 3

Associated Drugs

Tigilanol Tiglate 60
Carprofen 21
Gabapentin 18
Maropitant Citrate 16
Diphenhydramine 16
Famotidine 14
Prednisone 11
Dexmedetomidine 11
Butorphanol 11
Propofol 10
Hydromorphone 8
Ceftiofur Crystalline Free Acid 7
Buprenorphine 7
Meloxicam 6
Atipamezole 6
Butorphanol Tartrate 6
Moxidectin 5
Bupivacaine Lipsome Injectable Suspension 5
Melarsomine Dihydrochloride 5
Bupivacaine 5

Nationwide reactions with similar profiles

Two openFDA-derived peer sets for Injection site serous discharge, both floored at ≥50 reports so the neighborhoods stay in the advertised mass (the volume chart above is the unfloored photo-finish strip).

Similar death-coded share

Nearest other reactions by death-coded share (7.9% here), distinct from the volume row.

What to do with this reaction

A report does not prove a drug caused the reaction; consult a veterinarian before acting on this data.

Source: FDA Center for Veterinary Medicine openFDA Animal & Veterinary Adverse Events (CVM AER) · 2025

openFDA Animal & Veterinary Adverse Events (FDA CVM) for Injection site serous discharge (#1229 of 2,481 by report volume); death-coded 7.9%. PlainBreed reaction plate · death-coded share stamp 7.9% · vintage 2025.

Informational only. FDA adverse-event reports are voluntary and do not prove causation; consult a veterinarian before acting on them. Verify with FDA CVM →