Reaction profile

The FDA adverse-event record for increased sweating

238 FDA adverse-event reports reference increased sweating (VeDDRA 974). Plate codes and volume neighbourhood below; species, breeds, and drugs follow.

#961 of 2,481
by report volume (all reactions)
238
reports citing this reaction
10.1%
death-coded share
Horse
most-affected species

Release-over-release change

What changed in the latest FDA data snapshot

PlainBreed reconstructed the prior snapshot from dated openFDA partitions through 2025 Q4, then compared it with the 2026-07-27 openFDA export. Increased sweating has 238 reports now versus 236 in that prior snapshot: 2 more (0.8%).

Report change
+2
Death-coded reports
+0
Death-coded share
−0.1 pts

This compares reported-event counts in two source snapshots. It does not establish a change in real-world risk, product safety, or disease incidence.

Subscribe to Increased sweating changes

FDA AER · VeDDRA plate

Code 974 VOL-LOW

VOL-LOW · DEATH-ELEV · MID-PACK · PHOTO-FINISH · SPECIES-HORSE · DRUG-LEAD · DESK-WIDE · BOOK-FULL

  • VOL-LOW 238 reports
  • DEATH-ELEV 10.1%
  • MID-PACK #961/2481
  • PHOTO-FINISH Drug schedule prescri…
  • SPECIES-HORSE Horse · 154
  • DRUG-LEAD Pergolide Mesylate · 31
  • DESK-WIDE 20 breeds
  • BOOK-FULL 8/8 fields

Nearest volume peer: Drug schedule prescribing error (±0 reports)

Instrument codes from this reaction’s FDA CVM adverse-event extract: volume band, death-coded share, corpus rank, photo-finish peer, lead species, lead drug, breed desk, and book completeness. Not a clinical diagnosis.

Report-volume neighbourhood around Increased sweating

Highest and lowest poles plus nearest volume peers, not a full 2,500-reaction corpus board reprint.

Vomiting · highest174348Aural haematoma · near239Oral mass · near239Drug schedule prescri… · near238Increased sweating · this re…238Blinking · near237Urinary tract neoplas… · low…10
FDA AER report volume · neighbourhood around Increased sweating

What the FDA AER plate says about Increased sweating

Signature read: report volume at 238 (#961 of 2,481) is the standout scale stamp on Increased sweating. Report volume sits in the middle third of the reaction corpus. 24 of 238 reports were death-coded (10.1% of named reports, not a population mortality rate). Nearest volume peer: Drug schedule prescribing error (±0 reports). Lead species Horse (154). Lead co-reported drug Pergolide Mesylate (31).

Read these counts as reporting volume, not risk: per our methodology, Lead co-reported drug Pergolide Mesylate appears in filings alongside this reaction; that is association, not causation. Browse the full reactions index or the about page for how PlainBreed frames FDA CVM extracts.

Species Most Affected

Horse 154
Human 35
Dog 27
Cat 10
Cattle 9
Donkey 3

Breeds Most Affected

Unknown 39
Quarter Horse 36
Horse (unknown) 20
Thoroughbred 17
Warmblood (unspecified) 11
Arab 8
Crossbred Equine/horse 8
Domestic Shorthair 6
Standardbred - American 5
Tennessee Walking Horse 4

Associated Drugs

Pergolide Mesylate 31
Ceftiofur Crystalline Free Acid 14
Nitenpyram 11
Clenbuterol Hydrochloride 8
Polysulfated Glycosaminoglycan 8
Gentamicin Sulfate 8
Enrofloxacin 7
Detomidine Hydrochloride 7
Flunixin Meglumine 5
Milbemycin Oxime + Spinosad 5
Phenylbutazone 5
Afoxolaner 5
Vit E/ Selenite Inj Solution 5
Furosemide Injection 5
Ivermectin(1.55%)/Praziquantel(7.75%) Paste 4
Flunixin Meglumine Injectable 4
Clodronate Disodium 4
Tilmicosin 4
Oxytetracycline 3
Ponazuril 3

Nationwide reactions with similar profiles

Two openFDA-derived peer sets for Increased sweating, both floored at ≥50 reports so the neighborhoods stay in the advertised mass (the volume chart above is the unfloored photo-finish strip).

Similar report volume

Nearest other reactions by FDA report count (238 here).

Similar death-coded share

Nearest other reactions by death-coded share (10.1% here), distinct from the volume row.

What to do with this reaction

A report does not prove a drug caused the reaction; consult a veterinarian before acting on this data.

Source: FDA Center for Veterinary Medicine openFDA Animal & Veterinary Adverse Events (CVM AER) · 2025

openFDA Animal & Veterinary Adverse Events (FDA CVM) for Increased sweating (#961 of 2,481 by report volume); death-coded 10.1%. PlainBreed reaction plate · report volume stamp 238 · vintage 2025.

Informational only. FDA adverse-event reports are voluntary and do not prove causation; consult a veterinarian before acting on them. Verify with FDA CVM →