Increased sweating

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VeDDRA Code: 974

230 adverse event reports referencing this reaction

230
Total Reports
23
Deaths
1000.0%
Death Rate

Species Most Affected

Horse 147
Human 34
Dog 27
Cat 10
Cattle 9
Donkey 3

Breeds Most Affected

Unknown 38
Quarter Horse 36
Horse (unknown) 20
Thoroughbred 17
Warmblood (unspecified) 10
Arab 8
Crossbred Equine/horse 8
Domestic Shorthair 6
Tennessee Walking Horse 4
Miniature 4

Associated Drugs

Pergolide Mesylate 30
Ceftiofur Crystalline Free Acid 14
Nitenpyram 11
Clenbuterol Hydrochloride 8
Polysulfated Glycosaminoglycan 8
Gentamicin Sulfate 8
Enrofloxacin 7
Detomidine Hydrochloride 6
Flunixin Meglumine 5
Milbemycin Oxime + Spinosad 5
Afoxolaner 5
Vit E/ Selenite Inj Solution 5
Phenylbutazone 4
Ivermectin(1.55%)/Praziquantel(7.75%) Paste 4
Flunixin Meglumine Injectable 4
Clodronate Disodium 4
Tilmicosin 4
Oxytetracycline 3
Ponazuril 3
Dinoprost Tromethamine 3

Data Summary

Metric Value
Total reports referencing reaction 230
Reports with fatal outcome 23
Case-fatality rate (reported events) 1000.0%
Species observed 6
Breeds observed 20
Drugs associated with reaction 20

Source: FDA Center for Veterinary Medicine — Adverse Event Reporting (CVM AER); reaction term coded under VeDDRA 974.

Increased sweating Reaction Insights

The FDA Center for Veterinary Medicine database currently lists 230 adverse event reports that reference Increased sweating as a reaction term, including 23 reports with a death outcome — a 1000.0% case-fatality figure calculated across only those events where this reaction was coded. The reaction is indexed in the openFDA system under VeDDRA code 974, the standardized veterinary dictionary used to normalize clinical signs across submitters. Because reports are voluntary and often describe multiple concurrent signs per animal, the volume here reflects reporting intensity rather than true incidence in the broader pet population.

Increased sweating appears most frequently in reports for Horse (147 reports), Human (34 reports), Dog (27 reports) — with Horse dominating at 147 entries. Within those species, the breeds most often named alongside this reaction are Unknown (38), Quarter Horse (36), Horse (unknown) (20). These distributions are influenced both by underlying breed popularity and by how veterinarians and owners code a given clinical sign, so they should be interpreted as a reporting fingerprint rather than a pure susceptibility ranking.

The drugs most commonly co-reported with Increased sweating are Pergolide Mesylate (30 reports), Ceftiofur Crystalline Free Acid (14 reports), Nitenpyram (11 reports), Clenbuterol Hydrochloride (8 reports), with Pergolide Mesylate appearing alongside this reaction in 30 submissions. Co-reporting does not establish that any specific product caused the reaction — FDA CVM data captures temporal association only. The value of these aggregates is in flagging which therapeutic classes appear repeatedly alongside a given clinical sign, so owners and veterinarians can ask targeted questions about medications currently in use.

Source: FDA Center for Veterinary Medicine — Adverse Event Reports FDA Center for Veterinary Medicine — Adverse Event Reports Data reflects voluntary submissions and may not represent actual incidence rates

Related

Data sourced from official AKC, AVMA, ACVO, and breed-club veterinary references. See our methodology for details. Retrieved and formatted by PlainBreed Editorial