Reaction profile

The FDA adverse-event record for intrauterine death

16 FDA adverse-event reports reference intrauterine death (VeDDRA 792). See the species, breeds, and drugs most associated with it below.

16
reports citing this reaction
75.0%
death-coded share
Dog
most-affected species
Spinosad
most-associated drug
Verify with FDA CVM →
16
Total Reports
12
Deaths
75.0%
Death Rate

Species Most Affected

Dog 13
Pig 1
Sheep 1
Goat 1

Breeds Most Affected

Spaniel - King Charles Cavalier 2
Bulldog - French 2
Schnauzer (unspecified) 1
Schnauzer - Miniature 1
Collie (unspecified) 1
Terrier - Yorkshire 1
Mountain Cur 1
Boxer (German Boxer) 1
Mountain Dog - Bernese 1
Retriever - Golden 1

Associated Drugs

Spinosad 4
Milbemycin Oxime + Praziquantel 2
Carprofen 2
Alfaxalone 2
Midazolam 2
Vitamins 1
Milbemycin Oxime + Spinosad 1
Nitenpyram 1
Flea Collar - Unknown Active Ingredient 1
Anesthetic 1
Fluralaner Chew Tablets 1
Pyrantel 1
Tylosin 1
Porcine Parvovirus, Killed Virus, Erysipelothrix Rhusiopathiae, Leptospira Canicola-Grippo-Hardjo-Icteroh-Pomona, Bacterin 1
Butorphanol 1
Butorphanol Tartrate 1
Ampicillin Trihydrate 1
Hydrocortisone Sodium Succinate 1
Isoflurane 1
Ketamine 1

Intrauterine death Reaction Insights

16 reports name Intrauterine death; 12 recorded a death outcome (75.0% of reported events, not a population-level mortality rate). VeDDRA code: 792.

By species: Dog (13 reports), Pig (1 reports), Sheep (1 reports). By breed: Spaniel - King Charles Cavalier (2), Bulldog - French (2), Schnauzer (unspecified) (1).

Most co-reported drugs: Spinosad (4 reports), Milbemycin Oxime + Praziquantel (2 reports), Carprofen (2 reports), Alfaxalone (2 reports).

Read these counts as reporting volume, not risk: per our methodology, co-reporting reflects temporal association captured in voluntary submissions, not proof that a drug caused this reaction. A widely-prescribed drug will rack up more raw co-reports at an identical true rate than a rarely-used one, so compare within similar-exposure products.

Source: FDA Center for Veterinary Medicine openFDA Animal & Veterinary Adverse Events (CVM AER) · 2025

Every figure on PlainBreed is rendered directly from FDA openFDA adverse event data, no number is typed in by an editor. This page draws directly on FDA openFDA data, no figure is typed in by an editor. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.