Reaction profile

The FDA adverse-event record for respiratory tract infection nos

422 FDA reports name respiratory tract infection nos, a high-volume reaction in the CVM extract (VeDDRA 1182). Plate stamps and neighbourhood peers follow.

#706 of 2,481
by report volume (all reactions)
422
reports citing this reaction
20.1%
death-coded share
Dog
most-affected species

Release-over-release change

What changed in the latest FDA data snapshot

PlainBreed reconstructed the prior snapshot from dated openFDA partitions through 2025 Q4, then compared it with the 2026-07-27 openFDA export. Respiratory tract infection NOS has 422 reports now versus 413 in that prior snapshot: 9 more (2.2%).

Report change
+9
Death-coded reports
+0
Death-coded share
−0.4 pts

This compares reported-event counts in two source snapshots. It does not establish a change in real-world risk, product safety, or disease incidence.

Subscribe to Respiratory tract infection NOS changes

FDA AER · VeDDRA plate

Code 1182 VOL-LOW

VOL-LOW · DEATH-HOT · MID-PACK · PHOTO-FINISH · SPECIES-DOG · DRUG-LEAD · DESK-WIDE · BOOK-FULL

  • VOL-LOW 422 reports
  • DEATH-HOT 20.1%
  • MID-PACK #706/2481
  • PHOTO-FINISH Anuria
  • SPECIES-DOG Dog · 189
  • DRUG-LEAD Milbemycin Oxime… · 60
  • DESK-WIDE 20 breeds
  • BOOK-FULL 8/8 fields

Nearest volume peer: Anuria (±1 reports)

Upper-third report volume drives the scale stamps on this plate; death-coded share and co-report peers follow. Not a clinical diagnosis.

High-volume neighbourhood around Respiratory tract infection NOS

Upper-third volume poles plus nearest peers, not a full reaction corpus board reprint.

Vomiting · highest174348Decreased heart rate · near424Anuria · near423Decreased percentage… · near423Respiratory tract inf… · thi…422Intervertebral disc d… · near420Urinary tract neoplas… · low…10
FDA AER report volume · neighbourhood around Respiratory tract infection NOS

What the FDA AER plate says about Respiratory tract infection NOS

Signature read: 85 death-coded reports is a heavy tail count for Respiratory tract infection NOS in the CVM extract. Report volume is upper-third scale: 422 named reports in the openFDA extract. 85 of 422 reports were death-coded (20.1% of named reports, not a population mortality rate). Nearest volume peer: Anuria (±1 reports). Lead species Dog (189). Lead co-reported drug Milbemycin Oxime + Spinosad (60).

Read these counts as reporting volume, not risk: per our methodology, Lead co-reported drug Milbemycin Oxime + Spinosad appears in filings alongside this reaction; that is association, not causation. Browse the full reactions index or the about page for how PlainBreed frames FDA CVM extracts.

Species Most Affected

Dog 189
Cat 188
Cattle 31
Human 4
Horse 3
Chicken 2
Rat 1
Rabbit 1
Other Birds 1
Sheep 1

Breeds Most Affected

Domestic Shorthair 108
Domestic Longhair 20
Retriever - Labrador 15
Cat (unknown) 13
Crossbred Canine/dog 13
Domestic Mediumhair 12
Shih Tzu 11
Cattle (other) 10
Cat (other) 10
Chihuahua 7

Associated Drugs

Milbemycin Oxime + Spinosad 60
Imidacloprid + Moxidectin 24
Cefovecin 24
Oclacitinib Maleate 24
Trilostane 22
Maropitant Citrate 21
Enrofloxacin 19
Gabapentin 19
Frunevetmab 15
Spinosad 14
Selamectin 14
Meloxicam 13
Doxycycline 12
Bexagliflozin 12
Velagliflozin Proline Monohydrate 12
Cyclosporine 11
Moxidectin 11
Carprofen 11
Lotilaner 11
Amoxicillin + Clavulanic Acid 11

Nationwide reactions with similar profiles

Two openFDA-derived peer sets for Respiratory tract infection NOS, both floored at ≥50 reports so the neighborhoods stay in the advertised mass (the volume chart above is the unfloored photo-finish strip).

Similar death-coded share

Nearest other reactions by death-coded share (20.1% here), distinct from the volume row.

What to do with this reaction

A report does not prove a drug caused the reaction; consult a veterinarian before acting on this data.

Source: FDA Center for Veterinary Medicine openFDA Animal & Veterinary Adverse Events (CVM AER) · 2025

openFDA Animal & Veterinary Adverse Events (FDA CVM) for Respiratory tract infection NOS (#706 of 2,481 by report volume); death-coded 20.1%. PlainBreed reaction plate · death-coded report count stamp 85 · vintage 2025.

Informational only. FDA adverse-event reports are voluntary and do not prove causation; consult a veterinarian before acting on them. Verify with FDA CVM →