Respiratory tract infection NOS

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VeDDRA Code: 1182

387 adverse event reports referencing this reaction

387
Total Reports
78
Deaths
2020.0%
Death Rate

Species Most Affected

Dog 179
Cat 168
Cattle 27
Horse 3
Human 3
Chicken 2
Rat 1
Rabbit 1
Other Birds 1
Sheep 1

Breeds Most Affected

Domestic Shorthair 97
Retriever - Labrador 15
Domestic Longhair 14
Cat (unknown) 13
Crossbred Canine/dog 13
Domestic Mediumhair 11
Shih Tzu 11
Cat (other) 9
Boxer (German Boxer) 7
Maine Coon 6

Associated Drugs

Milbemycin Oxime + Spinosad 59
Imidacloprid + Moxidectin 24
Oclacitinib Maleate 24
Trilostane 22
Cefovecin 21
Enrofloxacin 19
Spinosad 14
Selamectin 13
Doxycycline 13
Gabapentin 12
Amoxicillin + Clavulanic Acid 12
Cyclosporine 11
Moxidectin 11
Maropitant Citrate 11
Meloxicam 10
Pradofloxacin 10
Frunevetmab 10
Bexagliflozin 9
Azithromycin 9
Bedinvetmab 9

Data Summary

Metric Value
Total reports referencing reaction 387
Reports with fatal outcome 78
Case-fatality rate (reported events) 2020.0%
Species observed 10
Breeds observed 20
Drugs associated with reaction 20

Source: FDA Center for Veterinary Medicine — Adverse Event Reporting (CVM AER); reaction term coded under VeDDRA 1182.

Respiratory tract infection NOS Reaction Insights

The FDA Center for Veterinary Medicine database currently lists 387 adverse event reports that reference Respiratory tract infection NOS as a reaction term, including 78 reports with a death outcome — a 2020.0% case-fatality figure calculated across only those events where this reaction was coded. The reaction is indexed in the openFDA system under VeDDRA code 1182, the standardized veterinary dictionary used to normalize clinical signs across submitters. Because reports are voluntary and often describe multiple concurrent signs per animal, the volume here reflects reporting intensity rather than true incidence in the broader pet population.

Respiratory tract infection NOS appears most frequently in reports for Dog (179 reports), Cat (168 reports), Cattle (27 reports) — with Dog dominating at 179 entries. Within those species, the breeds most often named alongside this reaction are Domestic Shorthair (97), Retriever - Labrador (15), Domestic Longhair (14). These distributions are influenced both by underlying breed popularity and by how veterinarians and owners code a given clinical sign, so they should be interpreted as a reporting fingerprint rather than a pure susceptibility ranking.

The drugs most commonly co-reported with Respiratory tract infection NOS are Milbemycin Oxime + Spinosad (59 reports), Imidacloprid + Moxidectin (24 reports), Oclacitinib Maleate (24 reports), Trilostane (22 reports), with Milbemycin Oxime + Spinosad appearing alongside this reaction in 59 submissions. Co-reporting does not establish that any specific product caused the reaction — FDA CVM data captures temporal association only. The value of these aggregates is in flagging which therapeutic classes appear repeatedly alongside a given clinical sign, so owners and veterinarians can ask targeted questions about medications currently in use.

Source: FDA Center for Veterinary Medicine — Adverse Event Reports FDA Center for Veterinary Medicine — Adverse Event Reports Data reflects voluntary submissions and may not represent actual incidence rates

Related

Data sourced from official AKC, AVMA, ACVO, and breed-club veterinary references. See our methodology for details. Retrieved and formatted by PlainBreed Editorial