Reaction profile

The FDA adverse-event record for nerve pain nos

30 FDA adverse-event reports reference nerve pain nos (VeDDRA 1640). See the species, breeds, and drugs most associated with it below.

30
reports citing this reaction
10.0%
death-coded share
Dog
most-affected species
Milbemycin Oxime + Spinosad
most-associated drug
Verify with FDA CVM →
30
Total Reports
3
Deaths
10.0%
Death Rate

Species Most Affected

Dog 23
Human 4
Cat 3

Breeds Most Affected

Unknown 4
Bulldog - French 2
Domestic Shorthair 2
Dog (other) 1
Maltese 1
Crossbred Canine/dog 1
Spaniel - King Charles Cavalier 1
Bulldog 1
Terrier - Jack Russell 1
Greyhound 1

Associated Drugs

Milbemycin Oxime + Spinosad 7
Carprofen 5
Spinosad 3
Ivermectin + Pyrantel As Pamoate Salt 3
Polysulfated Glycosaminoglycan 2
Trilostane 2
Gabapentin 2
Diphenhydramine 2
Bedinvetmab 2
Fluralaner Spot-On Solution 2
Metaflumizone + Amitraz 1
Acetylcysteine 1
Ivermectin 1
Doramectin; Phenol 1
Recombinant Human Insulin 1
Levothyroxine 1
Levetiracetam 1
Pimobendan 1
Oclacitinib Maleate 1
Amlodipine 1

Nerve pain NOS Reaction Insights

30 reports name Nerve pain NOS; 3 recorded a death outcome (10.0% of reported events, not a population-level mortality rate). VeDDRA code: 1640.

By species: Dog (23 reports), Human (4 reports), Cat (3 reports). By breed: Unknown (4), Bulldog - French (2), Domestic Shorthair (2).

Most co-reported drugs: Milbemycin Oxime + Spinosad (7 reports), Carprofen (5 reports), Spinosad (3 reports), Ivermectin + Pyrantel As Pamoate Salt (3 reports).

Read these counts as reporting volume, not risk: per our methodology, co-reporting reflects temporal association captured in voluntary submissions, not proof that a drug caused this reaction. A widely-prescribed drug will rack up more raw co-reports at an identical true rate than a rarely-used one, so compare within similar-exposure products.

Source: FDA Center for Veterinary Medicine openFDA Animal & Veterinary Adverse Events (CVM AER) · 2025

Every figure on PlainBreed is rendered directly from FDA openFDA adverse event data, no number is typed in by an editor. This page draws directly on FDA openFDA data, no figure is typed in by an editor. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.