Reaction profile

The FDA adverse-event record for blood in urine

1,845 FDA adverse-event reports reference blood in urine (VeDDRA 1956). See the species, breeds, and drugs most associated with it below.

1,845
reports citing this reaction
18.9%
death-coded share
Dog
most-affected species
Carprofen
most-associated drug
Verify with FDA CVM →
1,845
Total Reports
348
Deaths
18.9%
Death Rate

Species Most Affected

Dog 1,495
Cat 326
Horse 19
Human 1
Cattle 1
Pig 1
Rabbit 1
Goat 1

Breeds Most Affected

Domestic Shorthair 200
Retriever - Labrador 195
Crossbred Canine/dog 88
Boxer (German Boxer) 59
Terrier - Yorkshire 50
Retriever - Golden 49
Chihuahua 46
Shepherd Dog - German 46
Shih Tzu 46
Terrier - Bull - American Pit 42

Associated Drugs

Carprofen 238
Milbemycin Oxime + Spinosad 180
Bedinvetmab 179
Oclacitinib Maleate 143
Trilostane 135
Maropitant Citrate 113
Gabapentin 88
Moxidectin 70
Fluralaner Chew Tablets 70
Meloxicam 64
Cefovecin 62
Spinosad 56
Prednisone 56
Buprenorphine 49
Tramadol 47
Famotidine 45
Afoxolaner 43
Enrofloxacin 41
Robenacoxib 39
Bexagliflozin 38

Blood in urine Reaction Insights

1,845 reports name Blood in urine; 348 recorded a death outcome (18.9% of reported events, not a population-level mortality rate). VeDDRA code: 1956.

By species: Dog (1,495 reports), Cat (326 reports), Horse (19 reports). By breed: Domestic Shorthair (200), Retriever - Labrador (195), Crossbred Canine/dog (88).

Most co-reported drugs: Carprofen (238 reports), Milbemycin Oxime + Spinosad (180 reports), Bedinvetmab (179 reports), Oclacitinib Maleate (143 reports).

Read these counts as reporting volume, not risk: per our methodology, co-reporting reflects temporal association captured in voluntary submissions, not proof that a drug caused this reaction. A widely-prescribed drug will rack up more raw co-reports at an identical true rate than a rarely-used one, so compare within similar-exposure products.

Source: FDA Center for Veterinary Medicine openFDA Animal & Veterinary Adverse Events (CVM AER) · 2025

Every figure on PlainBreed is rendered directly from FDA openFDA adverse event data, no number is typed in by an editor. This page draws directly on FDA openFDA data, no figure is typed in by an editor. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.