Reaction profile

The FDA adverse-event record for blood in urine

1,952 FDA reports name blood in urine, a high-volume reaction in the CVM extract (VeDDRA 1956). Plate stamps and neighbourhood peers follow.

#239 of 2,481
by report volume (all reactions)
1,952
reports citing this reaction
18.3%
death-coded share
Dog
most-affected species

Release-over-release change

What changed in the latest FDA data snapshot

PlainBreed reconstructed the prior snapshot from dated openFDA partitions through 2025 Q4, then compared it with the 2026-07-27 openFDA export. Blood in urine has 1,952 reports now versus 1,913 in that prior snapshot: 39 more (2.0%).

Report change
+39
Death-coded reports
+3
Death-coded share
−0.2 pts

This compares reported-event counts in two source snapshots. It does not establish a change in real-world risk, product safety, or disease incidence.

Subscribe to Blood in urine changes

FDA AER · VeDDRA plate

Code 1956 VOL-MID

VOL-MID · DEATH-ELEV · TOP-DECILE · PHOTO-FINISH · SPECIES-DOG · DRUG-LEAD · DESK-WIDE · BOOK-FULL

  • VOL-MID 1,952 reports
  • DEATH-ELEV 18.3%
  • TOP-DECILE #239/2481
  • PHOTO-FINISH Icterus
  • SPECIES-DOG Dog · 1,568
  • DRUG-LEAD Carprofen · 246
  • DESK-WIDE 20 breeds
  • BOOK-FULL 8/8 fields

Nearest volume peer: Icterus (±2 reports)

Upper-third report volume drives the scale stamps on this plate; death-coded share and co-report peers follow. Not a clinical diagnosis.

High-volume neighbourhood around Blood in urine

Upper-third volume poles plus nearest peers, not a full reaction corpus board reprint.

Vomiting · highest174348Circling - neurologic… · near1965Elevated symmetrical… · near1964Blood in urine · this reacti…1952Icterus · near1950Elevated renal parame… · near1945Urinary tract neoplas… · low…10
FDA AER report volume · neighbourhood around Blood in urine

What the FDA AER plate says about Blood in urine

Signature read: 357 death-coded reports is a heavy tail count for Blood in urine in the CVM extract. Report volume is upper-third scale: 1,952 named reports in the openFDA extract. 357 of 1,952 reports were death-coded (18.3% of named reports, not a population mortality rate). Nearest volume peer: Icterus (±2 reports). Lead species Dog (1,568). Lead co-reported drug Carprofen (246).

Read these counts as reporting volume, not risk: per our methodology, Lead co-reported drug Carprofen appears in filings alongside this reaction; that is association, not causation. Browse the full reactions index or the about page for how PlainBreed frames FDA CVM extracts.

Species Most Affected

Dog 1,568
Cat 360
Horse 19
Human 1
Cattle 1
Pig 1
Rabbit 1
Goat 1

Breeds Most Affected

Domestic Shorthair 224
Retriever - Labrador 205
Crossbred Canine/dog 96
Boxer (German Boxer) 59
Retriever - Golden 52
Terrier - Yorkshire 51
Shepherd Dog - German 49
Chihuahua 48
Shih Tzu 48
Terrier - Bull - American Pit 45

Associated Drugs

Carprofen 246
Bedinvetmab 195
Milbemycin Oxime + Spinosad 181
Oclacitinib Maleate 160
Trilostane 144
Maropitant Citrate 125
Gabapentin 102
Moxidectin 74
Fluralaner Chew Tablets 70
Cefovecin 67
Meloxicam 66
Prednisone 59
Spinosad 56
Buprenorphine 51
Bexagliflozin 50
Famotidine 48
Tramadol 47
Robenacoxib 47
Enrofloxacin 43
Afoxolaner 43

Nationwide reactions with similar profiles

Two openFDA-derived peer sets for Blood in urine, both floored at ≥50 reports so the neighborhoods stay in the advertised mass (the volume chart above is the unfloored photo-finish strip).

Similar death-coded share

Nearest other reactions by death-coded share (18.3% here), distinct from the volume row.

What to do with this reaction

A report does not prove a drug caused the reaction; consult a veterinarian before acting on this data.

Source: FDA Center for Veterinary Medicine openFDA Animal & Veterinary Adverse Events (CVM AER) · 2025

openFDA Animal & Veterinary Adverse Events (FDA CVM) for Blood in urine (#239 of 2,481 by report volume); death-coded 18.3%. PlainBreed reaction plate · death-coded report count stamp 357 · vintage 2025.

Informational only. FDA adverse-event reports are voluntary and do not prove causation; consult a veterinarian before acting on them. Verify with FDA CVM →