Reaction profile

The FDA adverse-event record for external ear disorder nos

430 FDA reports name external ear disorder nos, a high-volume reaction in the CVM extract (VeDDRA 354). Plate stamps and neighbourhood peers follow.

#697 of 2,481
by report volume (all reactions)
430
reports citing this reaction
7.7%
death-coded share
Dog
most-affected species

Release-over-release change

What changed in the latest FDA data snapshot

PlainBreed reconstructed the prior snapshot from dated openFDA partitions through 2025 Q4, then compared it with the 2026-07-27 openFDA export. External ear disorder NOS has 430 reports now versus 425 in that prior snapshot: 5 more (1.2%).

Report change
+5
Death-coded reports
+0
Death-coded share
−0.1 pts

This compares reported-event counts in two source snapshots. It does not establish a change in real-world risk, product safety, or disease incidence.

Subscribe to External ear disorder NOS changes

FDA AER · VeDDRA plate

Code 354 VOL-LOW

VOL-LOW · DEATH-PAR · MID-PACK · PHOTO-FINISH · SPECIES-DOG · DRUG-LEAD · DESK-WIDE · BOOK-FULL

  • VOL-LOW 430 reports
  • DEATH-PAR 7.7%
  • MID-PACK #697/2481
  • PHOTO-FINISH Ecchymosis
  • SPECIES-DOG Dog · 336
  • DRUG-LEAD Milbemycin Oxime… · 75
  • DESK-WIDE 20 breeds
  • BOOK-FULL 8/8 fields

Nearest volume peer: Ecchymosis (±0 reports)

Upper-third report volume drives the scale stamps on this plate; death-coded share and co-report peers follow. Not a clinical diagnosis.

High-volume neighbourhood around External ear disorder NOS

Upper-third volume poles plus nearest peers, not a full reaction corpus board reprint.

Vomiting · highest174348Dermal cyst(s) · near433Erythematous rash · near432Food refusal · near431Ecchymosis · near430External ear disorder… · thi…430Urinary tract neoplas… · low…10
FDA AER report volume · neighbourhood around External ear disorder NOS

External ear disorder NOS: low death-coded share in the FDA AER plate

Signature read: 430 reports place External ear disorder NOS in the upper third of FDA AER volume (#697 of 2,481). Report volume is upper-third scale: 430 named reports in the openFDA extract. Death-coded share is lower-third: 33 of 430 reports (7.7% of named reports). Nearest volume peer: Ecchymosis (±0 reports). Lead species Dog (336). Lead co-reported drug Milbemycin Oxime + Spinosad (75).

Read these counts as reporting volume, not risk: per our methodology, Lead co-reported drug Milbemycin Oxime + Spinosad appears in filings alongside this reaction; that is association, not causation. Browse the full reactions index or the about page for how PlainBreed frames FDA CVM extracts.

Species Most Affected

Dog 336
Cat 79
Human 5
Pig 3
Cattle 3
Rabbit 3
Donkey 1

Breeds Most Affected

Retriever - Labrador 45
Domestic Shorthair 37
Crossbred Canine/dog 18
Retriever - Golden 16
Domestic (unspecified) 15
Terrier - Yorkshire 14
Chihuahua 14
Shih Tzu 12
Shepherd Dog - German 11
Spaniel - Cocker American 9

Associated Drugs

Milbemycin Oxime + Spinosad 75
Betamethasone + Florfenicol + Terbinafine 43
Selamectin 27
Spinosad 20
Oclacitinib Maleate 18
Milbemycin Oxime + Praziquantel 17
Carprofen 15
Imidacloprid + Moxidectin 14
Trilostane 14
Cefovecin Sodium 12
Moxidectin 12
Afoxolaner 12
Florfenicol + Mometasone Furoate + Terbinafine Hydrochloride 12
Clotrimazole, Gentamicin Sulfate, Mometasone Furoate Monohydrate 11
Prednisone 10
Ivermectin 9
Gabapentin 9
Maropitant Citrate 9
Cyclosporine 8
Nitenpyram 8

Nationwide reactions with similar profiles

Two openFDA-derived peer sets for External ear disorder NOS, both floored at ≥50 reports so the neighborhoods stay in the advertised mass (the volume chart above is the unfloored photo-finish strip).

Similar report volume

Nearest other reactions by FDA report count (430 here).

Similar death-coded share

Nearest other reactions by death-coded share (7.7% here), distinct from the volume row.

What to do with this reaction

A report does not prove a drug caused the reaction; consult a veterinarian before acting on this data.

Source: FDA Center for Veterinary Medicine openFDA Animal & Veterinary Adverse Events (CVM AER) · 2025

openFDA Animal & Veterinary Adverse Events (FDA CVM) for External ear disorder NOS (#697 of 2,481 by report volume); death-coded 7.7%. PlainBreed reaction plate · report volume stamp 430 · vintage 2025.

Informational only. FDA adverse-event reports are voluntary and do not prove causation; consult a veterinarian before acting on them. Verify with FDA CVM →