Reaction profile

The FDA adverse-event record for wry neck

13 FDA reports name wry neck, a lower-volume reaction in the CVM extract (VeDDRA 595). Plate stamps and neighbourhood peers follow.

#2373 of 2,481
by report volume (all reactions)
13
reports citing this reaction
30.8%
death-coded share
Dog
most-affected species

Release-over-release change

What changed in the latest FDA data snapshot

PlainBreed reconstructed the prior snapshot from dated openFDA partitions through 2025 Q4, then compared it with the 2026-07-27 openFDA export. Wry neck has 13 reports now versus 13 in that prior snapshot: 0 the same number of (0.0%).

Report change
+0
Death-coded reports
+0
Death-coded share
+0.0 pts

This compares reported-event counts in two source snapshots. It does not establish a change in real-world risk, product safety, or disease incidence.

Subscribe to Wry neck changes

FDA AER · VeDDRA plate

Code 595 VOL-TRACE

VOL-TRACE · DEATH-HOT · BOTTOM-DECILE · PHOTO-FINISH · SPECIES-DOG · DRUG-LEAD · DESK-WIDE · BOOK-FULL

  • VOL-TRACE 13 reports
  • DEATH-HOT 30.8%
  • BOTTOM-DECILE #2373/2481
  • PHOTO-FINISH Abnormal digital pulse
  • SPECIES-DOG Dog · 10
  • DRUG-LEAD Milbemycin Oxime… · 5
  • DESK-WIDE 11 breeds
  • BOOK-FULL 8/8 fields

Nearest volume peer: Abnormal digital pulse (±0 reports)

Upper-third death-coded share drives the outcome stamps on this plate; volume band, corpus rank, and co-report peers follow. Not a clinical diagnosis.

Lower-volume neighbourhood around Wry neck

Lower-third volume poles plus nearest peers, not a full reaction corpus board reprint.

Vomiting · highest174348Abnormal digital pulse · near13Acute haemorrhagic pa… · near13Acute jaundice · near13Application site mass… · near13Wry neck · this reaction13Urinary tract neoplas… · low…10
FDA AER report volume · neighbourhood around Wry neck

Wry neck: high death-coded share in the FDA AER plate

Signature read: 13 reports place Wry neck in the lower third of FDA AER volume (#2373 of 2,481). Report volume is lower-third scale: 13 named reports in the openFDA extract. Death-coded share is upper-third: 4 of 13 reports (30.8% of named reports). Nearest volume peer: Abnormal digital pulse (±0 reports). Lead species Dog (10). Lead co-reported drug Milbemycin Oxime + Spinosad (5).

Read these counts as reporting volume, not risk: per our methodology, A high death-coded share in FDA filings does not prove causation; co-reporting is voluntary temporal association only. Browse the full reactions index or the about page for how PlainBreed frames FDA CVM extracts.

Species Most Affected

Dog 10
Cat 2
Cattle 1

Breeds Most Affected

Domestic Shorthair 2
Pug 2
Spitz - German Pomeranian 1
Dog (other) 1
Lhasa Apso 1
Holstein-Friesian also known as Holstein 1
Dog (unknown) 1
Shih Tzu 1
Coton de Tuléar 1
Terrier (unspecified) 1

Associated Drugs

Milbemycin Oxime + Spinosad 5
Cyclosporine A 1
Metoclopramide 1
Diphenhydramine 1
Ceftiofur Crystalline Free Acid 1
Melarsomine Dihydrochloride Injection 1
Carprofen 1
Meloxicam 1
Betamethasone + Florfenicol + Terbinafine 1
Afoxolaner 1
Mirtazapine 1
Sarolaner 1
Bedinvetmab 1
Royal Canin Urinary So 1
Denamarin 1

What to do with this reaction

A report does not prove a drug caused the reaction; consult a veterinarian before acting on this data.

Source: FDA Center for Veterinary Medicine openFDA Animal & Veterinary Adverse Events (CVM AER) · 2025

openFDA Animal & Veterinary Adverse Events (FDA CVM) for Wry neck (#2373 of 2,481 by report volume); death-coded 30.8%. PlainBreed reaction plate · report volume stamp 13 · vintage 2025.

Informational only. FDA adverse-event reports are voluntary and do not prove causation; consult a veterinarian before acting on them. Verify with FDA CVM →