Reaction profile

The FDA adverse-event record for small intestine ulcer

215 FDA adverse-event reports reference small intestine ulcer (VeDDRA 1087). See the species, breeds, and drugs most associated with it below.

215
reports citing this reaction
53.5%
death-coded share
Dog
most-affected species
Deracoxib
most-associated drug
Verify with FDA CVM →
215
Total Reports
115
Deaths
53.5%
Death Rate

Species Most Affected

Dog 200
Cat 7
Horse 4
Cattle 3
Chicken 1

Breeds Most Affected

Retriever - Labrador 41
Crossbred Canine/dog 28
Rottweiler 13
Retriever - Golden 10
Cattle Dog - Australian (blue heeler, red heeler, Queensland cattledog) 9
Dog (unknown) 9
Mastiff 7
Boxer (German Boxer) 6
Shepherd Dog - German 5
Pug 4

Associated Drugs

Deracoxib 67
Firocoxib 53
Carprofen 38
Meloxicam 16
Maropitant Citrate 7
Firocoxib 227 Mg Chewable 5
Maropitant 4
Prednisone 4
Sucralfate 4
Milbemycin Oxime + Spinosad 3
Famotidine 3
Fluconazole 3
Gabapentin 3
Neomycin + Polymyxin + Bacitracin + Hydrocortisone Ophthalmic 3
Supplement 3
Fluid Therapy 3
Unknown Medication 3
Cyclosporine 3
Bacitracin + Neomycin + Polymyxin B 3
Cefpodoxime Proxetil 2

Small intestine ulcer Reaction Insights

215 reports name Small intestine ulcer; 115 recorded a death outcome (53.5% of reported events, not a population-level mortality rate). VeDDRA code: 1087.

By species: Dog (200 reports), Cat (7 reports), Horse (4 reports). By breed: Retriever - Labrador (41), Crossbred Canine/dog (28), Rottweiler (13).

Most co-reported drugs: Deracoxib (67 reports), Firocoxib (53 reports), Carprofen (38 reports), Meloxicam (16 reports).

Read these counts as reporting volume, not risk: per our methodology, co-reporting reflects temporal association captured in voluntary submissions, not proof that a drug caused this reaction. A widely-prescribed drug will rack up more raw co-reports at an identical true rate than a rarely-used one, so compare within similar-exposure products.

Source: FDA Center for Veterinary Medicine openFDA Animal & Veterinary Adverse Events (CVM AER) · 2025

Every figure on PlainBreed is rendered directly from FDA openFDA adverse event data, no number is typed in by an editor. This page draws directly on FDA openFDA data, no figure is typed in by an editor. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.