Small intestine ulcer

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VeDDRA Code: 1087

215 adverse event reports referencing this reaction

215
Total Reports
115
Deaths
5350.0%
Death Rate

Species Most Affected

Dog 200
Cat 7
Horse 4
Cattle 3
Chicken 1

Breeds Most Affected

Retriever - Labrador 41
Crossbred Canine/dog 28
Rottweiler 13
Retriever - Golden 10
Cattle Dog - Australian (blue heeler, red heeler, Queensland cattledog) 9
Dog (unknown) 9
Mastiff 7
Boxer (German Boxer) 6
Shepherd Dog - German 5
Pug 4

Associated Drugs

Deracoxib 67
Firocoxib 53
Carprofen 38
Meloxicam 16
Maropitant Citrate 7
Firocoxib 227 Mg Chewable 5
Maropitant 4
Prednisone 4
Sucralfate 4
Milbemycin Oxime + Spinosad 3
Famotidine 3
Fluconazole 3
Gabapentin 3
Neomycin + Polymyxin + Bacitracin + Hydrocortisone Ophthalmic 3
Supplement 3
Fluid Therapy 3
Unknown Medication 3
Cyclosporine 3
Bacitracin + Neomycin + Polymyxin B 3
Cefpodoxime Proxetil 2

Data Summary

Metric Value
Total reports referencing reaction 215
Reports with fatal outcome 115
Case-fatality rate (reported events) 5350.0%
Species observed 5
Breeds observed 20
Drugs associated with reaction 20

Source: FDA Center for Veterinary Medicine — Adverse Event Reporting (CVM AER); reaction term coded under VeDDRA 1087.

Small intestine ulcer Reaction Insights

The FDA Center for Veterinary Medicine database currently lists 215 adverse event reports that reference Small intestine ulcer as a reaction term, including 115 reports with a death outcome — a 5350.0% case-fatality figure calculated across only those events where this reaction was coded. The reaction is indexed in the openFDA system under VeDDRA code 1087, the standardized veterinary dictionary used to normalize clinical signs across submitters. Because reports are voluntary and often describe multiple concurrent signs per animal, the volume here reflects reporting intensity rather than true incidence in the broader pet population.

Small intestine ulcer appears most frequently in reports for Dog (200 reports), Cat (7 reports), Horse (4 reports) — with Dog dominating at 200 entries. Within those species, the breeds most often named alongside this reaction are Retriever - Labrador (41), Crossbred Canine/dog (28), Rottweiler (13). These distributions are influenced both by underlying breed popularity and by how veterinarians and owners code a given clinical sign, so they should be interpreted as a reporting fingerprint rather than a pure susceptibility ranking.

The drugs most commonly co-reported with Small intestine ulcer are Deracoxib (67 reports), Firocoxib (53 reports), Carprofen (38 reports), Meloxicam (16 reports), with Deracoxib appearing alongside this reaction in 67 submissions. Co-reporting does not establish that any specific product caused the reaction — FDA CVM data captures temporal association only. The value of these aggregates is in flagging which therapeutic classes appear repeatedly alongside a given clinical sign, so owners and veterinarians can ask targeted questions about medications currently in use.

Source: FDA Center for Veterinary Medicine — Adverse Event Reports FDA Center for Veterinary Medicine — Adverse Event Reports Data reflects voluntary submissions and may not represent actual incidence rates

Related

Data sourced from official AKC, AVMA, ACVO, and breed-club veterinary references. See our methodology for details. Retrieved and formatted by PlainBreed Editorial