Emesis (multiple)

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VeDDRA Code: 2082

18,161 adverse event reports referencing this reaction

18,161
Total Reports
925
Deaths
510.0%
Death Rate

Species Most Affected

Dog 15,996
Cat 2,140
Human 19
Unknown 2
Pig 2
Wolf 1
Dormouse 1

Breeds Most Affected

Crossbred Canine/dog 2,288
Retriever - Labrador 1,359
Domestic Shorthair 1,336
Chihuahua 802
Shih Tzu 681
Terrier - Yorkshire 679
Retriever - Golden 654
Shepherd Dog - German 478
Pit Bull 441
Dog (unknown) 375

Associated Drugs

Fluralaner Chew Tablets 3,130
Milbemycin Oxime + Spinosad 2,763
Fluralaner 13.64% 12-Week Chew 1,982
Spinosad 981
Pyrantel Pamoate;Sarolaner 880
Fluralaner Spot-On Solution 666
Febantel + Praziquantel + Pyrantel Pamoate 566
Ivermectin + Pyrantel As Pamoate Salt 534
Bedinvetmab 435
Afoxolaner 434
Maropitant Citrate 394
Moxidectin 393
Imidacloprid + Moxidectin 373
Fenbendazol Granules 342
Milbemycin Oxime + Praziquantel 340
Ivermectin + Pyrantel 330
Carprofen 286
Cyclosporine A 266
Oclacitinib Maleate 260
Nitenpyram 216

Data Summary

Metric Value
Total reports referencing reaction 18,161
Reports with fatal outcome 925
Case-fatality rate (reported events) 510.0%
Species observed 7
Breeds observed 20
Drugs associated with reaction 20

Source: FDA Center for Veterinary Medicine — Adverse Event Reporting (CVM AER); reaction term coded under VeDDRA 2082.

Emesis (multiple) Reaction Insights

The FDA Center for Veterinary Medicine database currently lists 18,161 adverse event reports that reference Emesis (multiple) as a reaction term, including 925 reports with a death outcome — a 510.0% case-fatality figure calculated across only those events where this reaction was coded. The reaction is indexed in the openFDA system under VeDDRA code 2082, the standardized veterinary dictionary used to normalize clinical signs across submitters. Because reports are voluntary and often describe multiple concurrent signs per animal, the volume here reflects reporting intensity rather than true incidence in the broader pet population.

Emesis (multiple) appears most frequently in reports for Dog (15,996 reports), Cat (2,140 reports), Human (19 reports) — with Dog dominating at 15,996 entries. Within those species, the breeds most often named alongside this reaction are Crossbred Canine/dog (2,288), Retriever - Labrador (1,359), Domestic Shorthair (1,336). These distributions are influenced both by underlying breed popularity and by how veterinarians and owners code a given clinical sign, so they should be interpreted as a reporting fingerprint rather than a pure susceptibility ranking.

The drugs most commonly co-reported with Emesis (multiple) are Fluralaner Chew Tablets (3,130 reports), Milbemycin Oxime + Spinosad (2,763 reports), Fluralaner 13.64% 12-Week Chew (1,982 reports), Spinosad (981 reports), with Fluralaner Chew Tablets appearing alongside this reaction in 3,130 submissions. Co-reporting does not establish that any specific product caused the reaction — FDA CVM data captures temporal association only. The value of these aggregates is in flagging which therapeutic classes appear repeatedly alongside a given clinical sign, so owners and veterinarians can ask targeted questions about medications currently in use.

Source: FDA Center for Veterinary Medicine — Adverse Event Reports FDA Center for Veterinary Medicine — Adverse Event Reports Data reflects voluntary submissions and may not represent actual incidence rates

Related

Data sourced from official AKC, AVMA, ACVO, and breed-club veterinary references. See our methodology for details. Retrieved and formatted by PlainBreed Editorial