Reaction profile

The FDA adverse-event record for lens disorder nos

123 FDA adverse-event reports reference lens disorder nos (VeDDRA 446). Plate codes and volume neighbourhood below; species, breeds, and drugs follow.

#1293 of 2,481
by report volume (all reactions)
123
reports citing this reaction
12.2%
death-coded share
Dog
most-affected species

Release-over-release change

What changed in the latest FDA data snapshot

PlainBreed reconstructed the prior snapshot from dated openFDA partitions through 2025 Q4, then compared it with the 2026-07-27 openFDA export. Lens disorder NOS has 123 reports now versus 122 in that prior snapshot: 1 more (0.8%).

Report change
+1
Death-coded reports
+0
Death-coded share
−0.1 pts

This compares reported-event counts in two source snapshots. It does not establish a change in real-world risk, product safety, or disease incidence.

Subscribe to Lens disorder NOS changes

FDA AER · VeDDRA plate

Code 446 VOL-LOW

VOL-LOW · DEATH-ELEV · MID-PACK · PHOTO-FINISH · SPECIES-DOG · DRUG-LEAD · DESK-WIDE · BOOK-FULL

  • VOL-LOW 123 reports
  • DEATH-ELEV 12.2%
  • MID-PACK #1293/2481
  • PHOTO-FINISH Birth defect
  • SPECIES-DOG Dog · 116
  • DRUG-LEAD Milbemycin Oxime… · 33
  • DESK-WIDE 20 breeds
  • BOOK-FULL 8/8 fields

Nearest volume peer: Birth defect (±0 reports)

Instrument codes from this reaction’s FDA CVM adverse-event extract: volume band, death-coded share, corpus rank, photo-finish peer, lead species, lead drug, breed desk, and book completeness. Not a clinical diagnosis.

Report-volume neighbourhood around Lens disorder NOS

Highest and lowest poles plus nearest volume peers, not a full 2,500-reaction corpus board reprint.

Vomiting · highest174348Birth defect · near123Hypomagnesaemic condi… · near123Joint ligament disord… · near123Lens disorder NOS · this rea…123Lung tumour · near123Urinary tract neoplas… · low…10
FDA AER report volume · neighbourhood around Lens disorder NOS

What the FDA AER plate says about Lens disorder NOS

Signature read: death-coded share at 12.2% is the most distinctive outcome stamp on Lens disorder NOS. Report volume sits in the middle third of the reaction corpus. 15 of 123 reports were death-coded (12.2% of named reports, not a population mortality rate). Nearest volume peer: Birth defect (±0 reports). Lead species Dog (116). Lead co-reported drug Milbemycin Oxime + Spinosad (33).

Read these counts as reporting volume, not risk: per our methodology, Lead co-reported drug Milbemycin Oxime + Spinosad appears in filings alongside this reaction; that is association, not causation. Browse the full reactions index or the about page for how PlainBreed frames FDA CVM extracts.

Species Most Affected

Dog 116
Cat 7

Breeds Most Affected

Crossbred Canine/dog 16
Retriever - Labrador 15
Shih Tzu 7
Maltese 7
Domestic Shorthair 7
Retriever - Golden 6
Spitz - German Pomeranian 4
Lhasa Apso 3
Dachshund (unspecified) 3
Beagle 3

Associated Drugs

Milbemycin Oxime + Spinosad 33
Fluralaner Chew Tablets 14
Spinosad 13
Trilostane 9
Recombinant Human Insulin 6
Diphenhydramine 5
Pimobendan 5
Grapiprant 5
Lotilaner 5
Ivermectin 4
Carprofen 4
Milbemycin Oxime + Praziquantel 4
Afoxolaner 4
Maropitant Citrate 4
Vetmedin Pimobendan Chewable 2.5 Mg Np 4
Oclacitinib Maleate 3
Milbemycin Oxime 3
Nitenpyram 3
Deracoxib 3
Insulin Injectable Vial 3

Nationwide reactions with similar profiles

Two openFDA-derived peer sets for Lens disorder NOS, both floored at ≥50 reports so the neighborhoods stay in the advertised mass (the volume chart above is the unfloored photo-finish strip).

Similar report volume

Nearest other reactions by FDA report count (123 here).

Similar death-coded share

Nearest other reactions by death-coded share (12.2% here), distinct from the volume row.

What to do with this reaction

A report does not prove a drug caused the reaction; consult a veterinarian before acting on this data.

Source: FDA Center for Veterinary Medicine openFDA Animal & Veterinary Adverse Events (CVM AER) · 2025

openFDA Animal & Veterinary Adverse Events (FDA CVM) for Lens disorder NOS (#1293 of 2,481 by report volume); death-coded 12.2%. PlainBreed reaction plate · death-coded share stamp 12.2% · vintage 2025.

Informational only. FDA adverse-event reports are voluntary and do not prove causation; consult a veterinarian before acting on them. Verify with FDA CVM →