Reaction profile

The FDA adverse-event record for lens disorder nos

120 FDA adverse-event reports reference lens disorder nos (VeDDRA 446). See the species, breeds, and drugs most associated with it below.

120
reports citing this reaction
12.5%
death-coded share
Dog
most-affected species
Milbemycin Oxime + Spinosad
most-associated drug
Verify with FDA CVM →
120
Total Reports
15
Deaths
12.5%
Death Rate

Species Most Affected

Dog 113
Cat 7

Breeds Most Affected

Crossbred Canine/dog 16
Retriever - Labrador 15
Shih Tzu 7
Maltese 7
Domestic Shorthair 7
Retriever - Golden 6
Spitz - German Pomeranian 4
Dachshund (unspecified) 3
Lhasa Apso 3
Beagle 3

Associated Drugs

Milbemycin Oxime + Spinosad 33
Fluralaner Chew Tablets 14
Spinosad 13
Trilostane 9
Recombinant Human Insulin 6
Pimobendan 5
Grapiprant 5
Lotilaner 5
Ivermectin 4
Diphenhydramine 4
Carprofen 4
Milbemycin Oxime + Praziquantel 4
Afoxolaner 4
Maropitant Citrate 4
Vetmedin Pimobendan Chewable 2.5 Mg Np 4
Oclacitinib Maleate 3
Milbemycin Oxime 3
Nitenpyram 3
Deracoxib 3
Metronidazole 3

Lens disorder NOS Reaction Insights

120 reports name Lens disorder NOS; 15 recorded a death outcome (12.5% of reported events, not a population-level mortality rate). VeDDRA code: 446.

By species: Dog (113 reports), Cat (7 reports). By breed: Crossbred Canine/dog (16), Retriever - Labrador (15), Shih Tzu (7).

Most co-reported drugs: Milbemycin Oxime + Spinosad (33 reports), Fluralaner Chew Tablets (14 reports), Spinosad (13 reports), Trilostane (9 reports).

Read these counts as reporting volume, not risk: per our methodology, co-reporting reflects temporal association captured in voluntary submissions, not proof that a drug caused this reaction. A widely-prescribed drug will rack up more raw co-reports at an identical true rate than a rarely-used one, so compare within similar-exposure products.

Source: FDA Center for Veterinary Medicine openFDA Animal & Veterinary Adverse Events (CVM AER) · 2025

Every figure on PlainBreed is rendered directly from FDA openFDA adverse event data, no number is typed in by an editor. This page draws directly on FDA openFDA data, no figure is typed in by an editor. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.