Reaction profile

The FDA adverse-event record for flaccid paralysis

45 FDA reports name flaccid paralysis, a lower-volume reaction in the CVM extract (VeDDRA 695). Plate stamps and neighbourhood peers follow.

#1794 of 2,481
by report volume (all reactions)
45
reports citing this reaction
31.1%
death-coded share
Dog
most-affected species
Verify with FDA CVM →

Release-over-release change

What changed in the latest FDA data snapshot

PlainBreed reconstructed the prior snapshot from dated openFDA partitions through 2025 Q4, then compared it with the 2026-07-27 openFDA export. Flaccid paralysis has 45 reports now versus 44 in that prior snapshot: 1 more (2.3%).

Report change
+1
Death-coded reports
+0
Death-coded share
−0.7 pts

This compares reported-event counts in two source snapshots. It does not establish a change in real-world risk, product safety, or disease incidence.

Subscribe to Flaccid paralysis changes

FDA AER · VeDDRA plate

Code 695 VOL-TRACE

VOL-TRACE · DEATH-HOT · MID-PACK · PHOTO-FINISH · SPECIES-DOG · DRUG-LEAD · DESK-WIDE · BOOK-FULL

  • VOL-TRACE 45 reports
  • DEATH-HOT 31.1%
  • MID-PACK #1794/2481
  • PHOTO-FINISH Application site disc…
  • SPECIES-DOG Dog · 32
  • DRUG-LEAD Milbemycin Oxime… · 5
  • DESK-WIDE 20 breeds
  • BOOK-FULL 8/8 fields

Nearest volume peer: Application site discharge NOS (±0 reports)

Upper-third death-coded share drives the outcome stamps on this plate; volume band, corpus rank, and co-report peers follow. Not a clinical diagnosis.

Lower-volume neighbourhood around Flaccid paralysis

Lower-third volume poles plus nearest peers, not a full reaction corpus board reprint.

Vomiting · highest174348Application site disc… · near45Buccal irritation · near45Chest tightness · near45Flaccid paralysis · this rea…45Lacrimation increased · near45Urinary tract neoplas… · low…10
FDA AER report volume · neighbourhood around Flaccid paralysis

Flaccid paralysis: high death-coded share in the FDA AER plate

Signature read: Flaccid paralysis's 31.1% death-coded share is among the highest in the openFDA reaction corpus. Report volume is lower-third scale: 45 named reports in the openFDA extract. Death-coded share is upper-third: 14 of 45 reports (31.1% of named reports). Nearest volume peer: Application site discharge NOS (±0 reports). Lead species Dog (32). Lead co-reported drug Milbemycin Oxime + Spinosad (5).

Read these counts as reporting volume, not risk: per our methodology, A high death-coded share in FDA filings does not prove causation; co-reporting is voluntary temporal association only. Browse the full reactions index or the about page for how PlainBreed frames FDA CVM extracts.

Species Most Affected

Dog 32
Cat 10
Horse 2
Turkey 1

Breeds Most Affected

Domestic Shorthair 7
Retriever - Labrador 4
Crossbred Canine/dog 4
Pit Bull 3
Quarter Horse 2
Shepherd Dog - German 2
Collie - Border 2
Mixed (Dog) 2
Pekingese 1
Turkey (unknown) 1

Associated Drugs

Milbemycin Oxime + Spinosad 5
Bedinvetmab 5
Spinosad 4
Carprofen 4
Ivermectin 3
Afoxolaner 3
Fluralaner 13.64% 12-Week Chew 3
Emodepside + Praziquantel 2
Moxidectin 2
Cefovecin 2
Imidacloprid + Moxidectin 2
Fluralaner Chew Tablets 2
Frunevetmab 2
Rabies 1
Fvrcp 1
Feline Leukemia Vaccine 1
Monensin Sodium 1
Sulfonamide (Unknown) 1
Ivermectin/Pyrantel Pamoate Chewable 136Mcg/326Mg 1
Melarsomine Dihydrochloride Injection 1

What to do with this reaction

A report does not prove a drug caused the reaction; consult a veterinarian before acting on this data.

Source: FDA Center for Veterinary Medicine openFDA Animal & Veterinary Adverse Events (CVM AER) · 2025

openFDA Animal & Veterinary Adverse Events (FDA CVM) for Flaccid paralysis (#1794 of 2,481 by report volume); death-coded 31.1%. PlainBreed reaction plate · death-coded share stamp 31.1% · vintage 2025.

Informational only. FDA adverse-event reports are voluntary and do not prove causation; consult a veterinarian before acting on them. Verify with FDA CVM →