Vials, Abnormal

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VeDDRA Code: 99033

611 adverse event reports referencing this reaction

611
Total Reports
0
Deaths
0.0%
Death Rate

Species Most Affected

Unknown 601
Human 7
Cat 1
Cattle 1
Dog 1

Breeds Most Affected

Unknown 608
Domestic (unspecified) 1
Holstein-Friesian also known as Holstein 1
Weimaraner 1

Associated Drugs

Insulin Injectable Vial 80
Moxidectin 79
Melarsomine Dihydrochloride Injection 76
Meloxicam 47
Prednisolone Sodium Succinate 45
Melarsomine Dihydrocloride Injectable 25Mg/Ml 18
Orbifloxacin 15
Dirlotapide 12
Polysulfated Glycosaminoglycan 11
Cefovecin 10
Ceftiofur Hydrochloride 9
Protamine Zinc Recombinant Human Insulin 9
Recombinant Human Insulin 9
Bupivacaine 9
Doramectin 8
Ceftiofur Sodium 8
Carprofen 7
Enrofloxacin 7
Velagliflozin Proline Monohydrate 6
Pimobendan 5

Data Summary

Metric Value
Total reports referencing reaction 611
Reports with fatal outcome 0
Case-fatality rate (reported events) 0.0%
Species observed 5
Breeds observed 4
Drugs associated with reaction 20

Source: FDA Center for Veterinary Medicine — Adverse Event Reporting (CVM AER); reaction term coded under VeDDRA 99033.

Vials, Abnormal Reaction Insights

The FDA Center for Veterinary Medicine database currently lists 611 adverse event reports that reference Vials, Abnormal as a reaction term, including 0 reports with a death outcome — a 0.0% case-fatality figure calculated across only those events where this reaction was coded. The reaction is indexed in the openFDA system under VeDDRA code 99033, the standardized veterinary dictionary used to normalize clinical signs across submitters. Because reports are voluntary and often describe multiple concurrent signs per animal, the volume here reflects reporting intensity rather than true incidence in the broader pet population.

Vials, Abnormal appears most frequently in reports for Unknown (601 reports), Human (7 reports), Cat (1 reports) — with Unknown dominating at 601 entries. Within those species, the breeds most often named alongside this reaction are Unknown (608), Domestic (unspecified) (1), Holstein-Friesian also known as Holstein (1). These distributions are influenced both by underlying breed popularity and by how veterinarians and owners code a given clinical sign, so they should be interpreted as a reporting fingerprint rather than a pure susceptibility ranking.

The drugs most commonly co-reported with Vials, Abnormal are Insulin Injectable Vial (80 reports), Moxidectin (79 reports), Melarsomine Dihydrochloride Injection (76 reports), Meloxicam (47 reports), with Insulin Injectable Vial appearing alongside this reaction in 80 submissions. Co-reporting does not establish that any specific product caused the reaction — FDA CVM data captures temporal association only. The value of these aggregates is in flagging which therapeutic classes appear repeatedly alongside a given clinical sign, so owners and veterinarians can ask targeted questions about medications currently in use.

Source: FDA Center for Veterinary Medicine — Adverse Event Reports FDA Center for Veterinary Medicine — Adverse Event Reports Data reflects voluntary submissions and may not represent actual incidence rates

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Data sourced from official AKC, AVMA, ACVO, and breed-club veterinary references. See our methodology for details. Retrieved and formatted by PlainBreed Editorial