Reaction profile

The FDA adverse-event record for autoimmune disorder nos

350 FDA reports name autoimmune disorder nos, a high-volume reaction in the CVM extract (VeDDRA 508). Plate stamps and neighbourhood peers follow.

#811 of 2,481
by report volume (all reactions)
350
reports citing this reaction
22.9%
death-coded share
Dog
most-affected species

Release-over-release change

What changed in the latest FDA data snapshot

PlainBreed reconstructed the prior snapshot from dated openFDA partitions through 2025 Q4, then compared it with the 2026-07-27 openFDA export. Autoimmune disorder NOS has 350 reports now versus 347 in that prior snapshot: 3 more (0.9%).

Report change
+3
Death-coded reports
+1
Death-coded share
+0.1 pts

This compares reported-event counts in two source snapshots. It does not establish a change in real-world risk, product safety, or disease incidence.

Subscribe to Autoimmune disorder NOS changes

FDA AER · VeDDRA plate

Code 508 VOL-LOW

VOL-LOW · DEATH-HOT · MID-PACK · PHOTO-FINISH · SPECIES-DOG · DRUG-LEAD · DESK-WIDE · BOOK-FULL

  • VOL-LOW 350 reports
  • DEATH-HOT 22.9%
  • MID-PACK #811/2481
  • PHOTO-FINISH Eye pain
  • SPECIES-DOG Dog · 330
  • DRUG-LEAD Milbemycin Oxime… · 45
  • DESK-WIDE 20 breeds
  • BOOK-FULL 8/8 fields

Nearest volume peer: Eye pain (±0 reports)

Upper-third report volume drives the scale stamps on this plate; death-coded share and co-report peers follow. Not a clinical diagnosis.

High-volume neighbourhood around Autoimmune disorder NOS

Upper-third volume poles plus nearest peers, not a full reaction corpus board reprint.

Vomiting · highest174348Pododermatitis · near351Autoimmune disorder N… · thi…350Eye pain · near350Locking Mechanism Abn… · near350Coma · near348Urinary tract neoplas… · low…10
FDA AER report volume · neighbourhood around Autoimmune disorder NOS

What the FDA AER plate says about Autoimmune disorder NOS

Signature read: 80 death-coded reports is a heavy tail count for Autoimmune disorder NOS in the CVM extract. Report volume is upper-third scale: 350 named reports in the openFDA extract. 80 of 350 reports were death-coded (22.9% of named reports, not a population mortality rate). Nearest volume peer: Eye pain (±0 reports). Lead species Dog (330). Lead co-reported drug Milbemycin Oxime + Spinosad (45).

Read these counts as reporting volume, not risk: per our methodology, Lead co-reported drug Milbemycin Oxime + Spinosad appears in filings alongside this reaction; that is association, not causation. Browse the full reactions index or the about page for how PlainBreed frames FDA CVM extracts.

Species Most Affected

Dog 330
Cat 17
Human 1
Donkey 1
Cattle 1

Breeds Most Affected

Crossbred Canine/dog 34
Dog (unknown) 24
Retriever - Labrador 19
Shepherd Dog - German 15
Shepherd Dog - Australian 11
Retriever - Golden 10
Dachshund (unspecified) 10
Shih Tzu 10
Mountain Dog - Bernese 9
Maltese 8

Associated Drugs

Milbemycin Oxime + Spinosad 45
Carprofen 37
Prednisone 27
Maropitant Citrate 19
Afoxolaner 19
Cefovecin 18
Bedinvetmab 17
Cyclosporine 15
Moxidectin 15
Oclacitinib Maleate 15
Ivermectin + Pyrantel As Pamoate Salt 15
Cefovecin Sodium 14
Enrofloxacin 14
Doxycycline 14
Spinosad 12
Famotidine 12
Selamectin 11
Meloxicam 11
Deracoxib 10
Milbemycin Oxime + Praziquantel 10

Nationwide reactions with similar profiles

Two openFDA-derived peer sets for Autoimmune disorder NOS, both floored at ≥50 reports so the neighborhoods stay in the advertised mass (the volume chart above is the unfloored photo-finish strip).

Similar report volume

Nearest other reactions by FDA report count (350 here).

Similar death-coded share

Nearest other reactions by death-coded share (22.9% here), distinct from the volume row.

What to do with this reaction

A report does not prove a drug caused the reaction; consult a veterinarian before acting on this data.

Source: FDA Center for Veterinary Medicine openFDA Animal & Veterinary Adverse Events (CVM AER) · 2025

openFDA Animal & Veterinary Adverse Events (FDA CVM) for Autoimmune disorder NOS (#811 of 2,481 by report volume); death-coded 22.9%. PlainBreed reaction plate · death-coded report count stamp 80 · vintage 2025.

Informational only. FDA adverse-event reports are voluntary and do not prove causation; consult a veterinarian before acting on them. Verify with FDA CVM →