Reaction profile

The FDA adverse-event record for droopy ear

116 FDA adverse-event reports reference droopy ear (VeDDRA 355). Plate codes and volume neighbourhood below; species, breeds, and drugs follow.

#1319 of 2,481
by report volume (all reactions)
116
reports citing this reaction
13.8%
death-coded share
Dog
most-affected species

Release-over-release change

What changed in the latest FDA data snapshot

PlainBreed reconstructed the prior snapshot from dated openFDA partitions through 2025 Q4, then compared it with the 2026-07-27 openFDA export. Droopy ear has 116 reports now versus 114 in that prior snapshot: 2 more (1.8%).

Report change
+2
Death-coded reports
+0
Death-coded share
−0.2 pts

This compares reported-event counts in two source snapshots. It does not establish a change in real-world risk, product safety, or disease incidence.

Subscribe to Droopy ear changes

FDA AER · VeDDRA plate

Code 355 VOL-LOW

VOL-LOW · DEATH-ELEV · MID-PACK · PHOTO-FINISH · SPECIES-DOG · DRUG-LEAD · DESK-WIDE · BOOK-FULL

  • VOL-LOW 116 reports
  • DEATH-ELEV 13.8%
  • MID-PACK #1319/2481
  • PHOTO-FINISH Multi-organ failure N…
  • SPECIES-DOG Dog · 72
  • DRUG-LEAD Milbemycin Oxime… · 15
  • DESK-WIDE 20 breeds
  • BOOK-FULL 8/8 fields

Nearest volume peer: Multi-organ failure NOS (±0 reports)

Instrument codes from this reaction’s FDA CVM adverse-event extract: volume band, death-coded share, corpus rank, photo-finish peer, lead species, lead drug, breed desk, and book completeness. Not a clinical diagnosis.

Report-volume neighbourhood around Droopy ear

Highest and lowest poles plus nearest volume peers, not a full 2,500-reaction corpus board reprint.

Vomiting · highest174348Droopy ear · this reaction116Multi-organ failure N… · near116Panniculitis · near116Subdued · near116Urinary tenesmus · near116Urinary tract neoplas… · low…10
FDA AER report volume · neighbourhood around Droopy ear

What the FDA AER plate says about Droopy ear

Signature read: report volume at 116 (#1319 of 2,481) is the standout scale stamp on Droopy ear. Report volume sits in the middle third of the reaction corpus. 16 of 116 reports were death-coded (13.8% of named reports, not a population mortality rate). Nearest volume peer: Multi-organ failure NOS (±0 reports). Lead species Dog (72). Lead co-reported drug Milbemycin Oxime + Spinosad (15).

Read these counts as reporting volume, not risk: per our methodology, Lead co-reported drug Milbemycin Oxime + Spinosad appears in filings alongside this reaction; that is association, not causation. Browse the full reactions index or the about page for how PlainBreed frames FDA CVM extracts.

Species Most Affected

Dog 72
Cat 22
Cattle 18
Horse 2
Pig 1
Rabbit 1

Breeds Most Affected

Domestic Shorthair 17
Retriever - Labrador 8
Shepherd Dog - German 8
Cattle (other) 7
Dog (unknown) 6
Crossbred Canine/dog 6
Aberdeen Angus 4
Boxer (German Boxer) 4
Corgi (unspecified) 3
Siberian Husky 3

Associated Drugs

Milbemycin Oxime + Spinosad 15
Florfenicol + Mometasone Furoate + Terbinafine Hydrochloride 12
Selamectin 7
Oclacitinib Maleate 7
Mirtazapine 7
Bedinvetmab 7
Afoxolaner 6
Prednisone 6
Moxidectin 5
Florfenicol/Terbinafine Hydrochloride/Mometasone Furoate 5
Maropitant Citrate 5
Betamethasone + Florfenicol + Terbinafine 4
Carprofen 4
Bovine Virus*5/Past M+Mh Lv/Lb 3
Genta/Momet/Clotrim Ear Oint 3
Anti-Il31 Mab Mcs Lot #1283563 3
Firocoxib 3
Monensin Sodium 2
Tulathromycin 2
Albendazole 2

Nationwide reactions with similar profiles

Two openFDA-derived peer sets for Droopy ear, both floored at ≥50 reports so the neighborhoods stay in the advertised mass (the volume chart above is the unfloored photo-finish strip).

Similar report volume

Nearest other reactions by FDA report count (116 here).

Similar death-coded share

Nearest other reactions by death-coded share (13.8% here), distinct from the volume row.

What to do with this reaction

A report does not prove a drug caused the reaction; consult a veterinarian before acting on this data.

Source: FDA Center for Veterinary Medicine openFDA Animal & Veterinary Adverse Events (CVM AER) · 2025

openFDA Animal & Veterinary Adverse Events (FDA CVM) for Droopy ear (#1319 of 2,481 by report volume); death-coded 13.8%. PlainBreed reaction plate · report volume stamp 116 · vintage 2025.

Informational only. FDA adverse-event reports are voluntary and do not prove causation; consult a veterinarian before acting on them. Verify with FDA CVM →