Application site moist eczema

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VeDDRA Code: 2065

29 adverse event reports referencing this reaction

29
Total Reports
1
Deaths
340.0%
Death Rate

Species Most Affected

Cat 19
Dog 10

Breeds Most Affected

Domestic Shorthair 12
Crossbred Canine/dog 4
Domestic Longhair 4
Shepherd Dog - German 2
Pit Bull 2
Domestic Mediumhair 1
Retriever - Golden 1
Dog (other) 1
Cat (other) 1
Cat (unknown) 1

Associated Drugs

Selamectin;Sarolaner 10
Imidacloprid + Moxidectin 9
Emodepside + Praziquantel 3
Flumethrin-Imidacloprid 2
Afoxolaner 2
Imidacloprid, Flumethrin 2
Vaccine 1
Rabies 1
Distemper 1
Ivermectin/Pyrantel Pamoate Chewable 68Mcg/163Mg 1
Fipronil 9.8%/S-Methoprene 8.8%/Cyphenothrin 5.2% Squeeze-On 1
Selamectin 1
Chlorhexidine + Ketoconazole + Phytosphingosine 1
Enrofloxacin 1
Oclacitinib 1
Diphenhydramine 1
Hydracortisone 1
Dexamethasone + Neomycin Sulfate + Thiabendazole 1
Praziquantel Pyrantel Pamoate 1
Imidacloprid, Moxidectin 1

Data Summary

Metric Value
Total reports referencing reaction 29
Reports with fatal outcome 1
Case-fatality rate (reported events) 340.0%
Species observed 2
Breeds observed 10
Drugs associated with reaction 20

Source: FDA Center for Veterinary Medicine — Adverse Event Reporting (CVM AER); reaction term coded under VeDDRA 2065.

Application site moist eczema Reaction Insights

The FDA Center for Veterinary Medicine database currently lists 29 adverse event reports that reference Application site moist eczema as a reaction term, including 1 reports with a death outcome — a 340.0% case-fatality figure calculated across only those events where this reaction was coded. The reaction is indexed in the openFDA system under VeDDRA code 2065, the standardized veterinary dictionary used to normalize clinical signs across submitters. Because reports are voluntary and often describe multiple concurrent signs per animal, the volume here reflects reporting intensity rather than true incidence in the broader pet population.

Application site moist eczema appears most frequently in reports for Cat (19 reports), Dog (10 reports) — with Cat dominating at 19 entries. Within those species, the breeds most often named alongside this reaction are Domestic Shorthair (12), Crossbred Canine/dog (4), Domestic Longhair (4). These distributions are influenced both by underlying breed popularity and by how veterinarians and owners code a given clinical sign, so they should be interpreted as a reporting fingerprint rather than a pure susceptibility ranking.

The drugs most commonly co-reported with Application site moist eczema are Selamectin;Sarolaner (10 reports), Imidacloprid + Moxidectin (9 reports), Emodepside + Praziquantel (3 reports), Flumethrin-Imidacloprid (2 reports), with Selamectin;Sarolaner appearing alongside this reaction in 10 submissions. Co-reporting does not establish that any specific product caused the reaction — FDA CVM data captures temporal association only. The value of these aggregates is in flagging which therapeutic classes appear repeatedly alongside a given clinical sign, so owners and veterinarians can ask targeted questions about medications currently in use.

Source: FDA Center for Veterinary Medicine — Adverse Event Reports FDA Center for Veterinary Medicine — Adverse Event Reports Data reflects voluntary submissions and may not represent actual incidence rates

Related

Data sourced from official AKC, AVMA, ACVO, and breed-club veterinary references. See our methodology for details. Retrieved and formatted by PlainBreed Editorial