Reaction profile

The FDA adverse-event record for application site moist eczema

Name: Application site moist eczema - FDA Animal Adverse Reaction
Creator: PlainBreed
License: https://creativecommons.org/publicdomain/zero/1.0/

29 FDA adverse-event reports reference application site moist eczema (VeDDRA 2065). See the species, breeds, and drugs most associated with it below.

29
reports citing this reaction: 3.4%
death-coded share: Cat
most-affected species: Selamectin;Sarolaner
most-associated drug

Compiled by PlainBreed Editorial, Pet Health Editorial Team

Verify with FDA CVM →

Total Reports

Deaths

3.4%

Death Rate

Species Most Affected

Cat 19

Dog 10

Breeds Most Affected

Domestic Shorthair 12

Crossbred Canine/dog 4

Domestic Longhair 4

Shepherd Dog - German 2

Pit Bull 2

Domestic Mediumhair 1

Retriever - Golden 1

Dog (other) 1

Cat (other) 1

Cat (unknown) 1

Associated Drugs

Selamectin;Sarolaner 10

Imidacloprid + Moxidectin 9

Emodepside + Praziquantel 3

Flumethrin-Imidacloprid 2

Afoxolaner 2

Imidacloprid, Flumethrin 2

Vaccine 1

Rabies 1

Distemper 1

Ivermectin/Pyrantel Pamoate Chewable 68Mcg/163Mg 1

Fipronil 9.8%/S-Methoprene 8.8%/Cyphenothrin 5.2% Squeeze-On 1

Selamectin 1

Chlorhexidine + Ketoconazole + Phytosphingosine 1

Enrofloxacin 1

Oclacitinib 1

Diphenhydramine 1

Hydracortisone 1

Dexamethasone + Neomycin Sulfate + Thiabendazole 1

Praziquantel Pyrantel Pamoate 1

Imidacloprid, Moxidectin 1

Application site moist eczema Reaction Insights

29 reports name Application site moist eczema; 1 recorded a death outcome (3.4% of reported events, not a population-level mortality rate). VeDDRA code: 2065.

By species: Cat (19 reports), Dog (10 reports). By breed: Domestic Shorthair (12), Crossbred Canine/dog (4), Domestic Longhair (4).

Most co-reported drugs: Selamectin;Sarolaner (10 reports), Imidacloprid + Moxidectin (9 reports), Emodepside + Praziquantel (3 reports), Flumethrin-Imidacloprid (2 reports).

Read these counts as reporting volume, not risk: per our methodology, co-reporting reflects temporal association captured in voluntary submissions, not proof that a drug caused this reaction. A widely-prescribed drug will rack up more raw co-reports at an identical true rate than a rarely-used one, so compare within similar-exposure products.

Source: FDA Center for Veterinary Medicine openFDA Animal & Veterinary Adverse Events (CVM AER) · 2025

Every figure on PlainBreed is rendered directly from FDA openFDA adverse event data, no number is typed in by an editor. This page draws directly on FDA openFDA data, no figure is typed in by an editor. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.