Heart pounding

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VeDDRA Code: 1514

105 adverse event reports referencing this reaction

105
Total Reports
13
Deaths
1240.0%
Death Rate

Species Most Affected

Dog 89
Human 7
Cat 6
Horse 2
Cattle 1

Breeds Most Affected

Chihuahua 7
Unknown 7
Retriever - Golden 4
Schnauzer - Miniature 4
Retriever - Labrador 4
Crossbred Canine/dog 4
Shih Tzu 4
Maltese 3
Dachshund (unspecified) 3
Shepherd Dog - Australian 3

Associated Drugs

Milbemycin Oxime + Spinosad 28
Pimobendan 25
Milbemycin Oxime + Praziquantel 6
Furosemide 5
Afoxolaner 5
Pyrantel Pamoate;Sarolaner 5
Spinosad 4
Carprofen 4
Benazepril 3
Enalapril 3
Cefovecin 3
Gabapentin 3
Rabies Vaccine 2
Bordetella Vaccine 2
Enalapril Maleate 2
Nitenpyram 2
Ivermectin + Pyrantel As Pamoate Salt 2
Phenylpropanolamine Hcl 2
Trilostane 2
Phenylpropropanolamine Hcl 2

Data Summary

Metric Value
Total reports referencing reaction 105
Reports with fatal outcome 13
Case-fatality rate (reported events) 1240.0%
Species observed 5
Breeds observed 20
Drugs associated with reaction 20

Source: FDA Center for Veterinary Medicine — Adverse Event Reporting (CVM AER); reaction term coded under VeDDRA 1514.

Heart pounding Reaction Insights

The FDA Center for Veterinary Medicine database currently lists 105 adverse event reports that reference Heart pounding as a reaction term, including 13 reports with a death outcome — a 1240.0% case-fatality figure calculated across only those events where this reaction was coded. The reaction is indexed in the openFDA system under VeDDRA code 1514, the standardized veterinary dictionary used to normalize clinical signs across submitters. Because reports are voluntary and often describe multiple concurrent signs per animal, the volume here reflects reporting intensity rather than true incidence in the broader pet population.

Heart pounding appears most frequently in reports for Dog (89 reports), Human (7 reports), Cat (6 reports) — with Dog dominating at 89 entries. Within those species, the breeds most often named alongside this reaction are Chihuahua (7), Unknown (7), Retriever - Golden (4). These distributions are influenced both by underlying breed popularity and by how veterinarians and owners code a given clinical sign, so they should be interpreted as a reporting fingerprint rather than a pure susceptibility ranking.

The drugs most commonly co-reported with Heart pounding are Milbemycin Oxime + Spinosad (28 reports), Pimobendan (25 reports), Milbemycin Oxime + Praziquantel (6 reports), Furosemide (5 reports), with Milbemycin Oxime + Spinosad appearing alongside this reaction in 28 submissions. Co-reporting does not establish that any specific product caused the reaction — FDA CVM data captures temporal association only. The value of these aggregates is in flagging which therapeutic classes appear repeatedly alongside a given clinical sign, so owners and veterinarians can ask targeted questions about medications currently in use.

Source: FDA Center for Veterinary Medicine — Adverse Event Reports FDA Center for Veterinary Medicine — Adverse Event Reports Data reflects voluntary submissions and may not represent actual incidence rates

Related

Data sourced from official AKC, AVMA, ACVO, and breed-club veterinary references. See our methodology for details. Retrieved and formatted by PlainBreed Editorial