Reaction profile

The FDA adverse-event record for heart pounding

108 FDA adverse-event reports reference heart pounding (VeDDRA 1514). Plate codes and volume neighbourhood below; species, breeds, and drugs follow.

#1351 of 2,481
by report volume (all reactions)
108
reports citing this reaction
13.0%
death-coded share
Dog
most-affected species

Release-over-release change

What changed in the latest FDA data snapshot

PlainBreed reconstructed the prior snapshot from dated openFDA partitions through 2025 Q4, then compared it with the 2026-07-27 openFDA export. Heart pounding has 108 reports now versus 106 in that prior snapshot: 2 more (1.9%).

Report change
+2
Death-coded reports
+1
Death-coded share
+0.7 pts

This compares reported-event counts in two source snapshots. It does not establish a change in real-world risk, product safety, or disease incidence.

Subscribe to Heart pounding changes

FDA AER · VeDDRA plate

Code 1514 VOL-LOW

VOL-LOW · DEATH-ELEV · MID-PACK · PHOTO-FINISH · SPECIES-DOG · DRUG-LEAD · DESK-WIDE · BOOK-FULL

  • VOL-LOW 108 reports
  • DEATH-ELEV 13.0%
  • MID-PACK #1351/2481
  • PHOTO-FINISH Acid-base disorder
  • SPECIES-DOG Dog · 90
  • DRUG-LEAD Milbemycin Oxime… · 28
  • DESK-WIDE 20 breeds
  • BOOK-FULL 8/8 fields

Nearest volume peer: Acid-base disorder (±0 reports)

Instrument codes from this reaction’s FDA CVM adverse-event extract: volume band, death-coded share, corpus rank, photo-finish peer, lead species, lead drug, breed desk, and book completeness. Not a clinical diagnosis.

Report-volume neighbourhood around Heart pounding

Highest and lowest poles plus nearest volume peers, not a full 2,500-reaction corpus board reprint.

Vomiting · highest174348Acid-base disorder · near108Discus prolapse · near108Heart pounding · this reacti…108Lick granuloma · near108Nasal cavity and sinu… · near108Urinary tract neoplas… · low…10
FDA AER report volume · neighbourhood around Heart pounding

What the FDA AER plate says about Heart pounding

Signature read: death-coded share at 13.0% is the most distinctive outcome stamp on Heart pounding. Report volume sits in the middle third of the reaction corpus. 14 of 108 reports were death-coded (13.0% of named reports, not a population mortality rate). Nearest volume peer: Acid-base disorder (±0 reports). Lead species Dog (90). Lead co-reported drug Milbemycin Oxime + Spinosad (28).

Read these counts as reporting volume, not risk: per our methodology, Lead co-reported drug Milbemycin Oxime + Spinosad appears in filings alongside this reaction; that is association, not causation. Browse the full reactions index or the about page for how PlainBreed frames FDA CVM extracts.

Species Most Affected

Dog 90
Human 7
Cat 7
Horse 2
Cattle 2

Breeds Most Affected

Chihuahua 8
Unknown 7
Retriever - Golden 4
Schnauzer - Miniature 4
Retriever - Labrador 4
Crossbred Canine/dog 4
Shih Tzu 4
Domestic Shorthair 4
Maltese 3
Dachshund (unspecified) 3

Associated Drugs

Milbemycin Oxime + Spinosad 28
Pimobendan 26
Furosemide 6
Afoxolaner 6
Milbemycin Oxime + Praziquantel 6
Pyrantel Pamoate;Sarolaner 5
Spinosad 4
Carprofen 4
Nitenpyram 3
Ivermectin + Pyrantel As Pamoate Salt 3
Benazepril 3
Enalapril 3
Cefovecin 3
Gabapentin 3
Rabies Vaccine 2
Bordetella Vaccine 2
Enalapril Maleate 2
Phenylpropanolamine Hcl 2
Trilostane 2
Phenylpropropanolamine Hcl 2

Nationwide reactions with similar profiles

Two openFDA-derived peer sets for Heart pounding, both floored at ≥50 reports so the neighborhoods stay in the advertised mass (the volume chart above is the unfloored photo-finish strip).

Similar report volume

Nearest other reactions by FDA report count (108 here).

Similar death-coded share

Nearest other reactions by death-coded share (13.0% here), distinct from the volume row.

What to do with this reaction

A report does not prove a drug caused the reaction; consult a veterinarian before acting on this data.

Source: FDA Center for Veterinary Medicine openFDA Animal & Veterinary Adverse Events (CVM AER) · 2025

openFDA Animal & Veterinary Adverse Events (FDA CVM) for Heart pounding (#1351 of 2,481 by report volume); death-coded 13.0%. PlainBreed reaction plate · death-coded share stamp 13.0% · vintage 2025.

Informational only. FDA adverse-event reports are voluntary and do not prove causation; consult a veterinarian before acting on them. Verify with FDA CVM →