Reaction profile

The FDA adverse-event record for injection site panniculitis

100 FDA adverse-event reports reference injection site panniculitis (VeDDRA 1053). See the species, breeds, and drugs most associated with it below.

100
reports citing this reaction
2.0%
death-coded share
Dog
most-affected species
Moxidectin
most-associated drug
Verify with FDA CVM →
100
Total Reports
2
Deaths
2.0%
Death Rate

Species Most Affected

Dog 82
Cat 17
Mouse 1

Breeds Most Affected

Retriever - Golden 10
Domestic Shorthair 9
Chihuahua 7
Dachshund (unspecified) 6
Maltese 5
Domestic Longhair 4
Terrier - Boston 4
Great Pyrenees 3
Retriever - Labrador 3
Boxer (German Boxer) 3

Associated Drugs

Moxidectin 37
Carprofen 14
Cefovecin 12
Melarsomine Dihydrochloride 10
Meloxicam 8
Rabies Vaccine, Killed Virus 4
Enrofloxacin 4
Methylprednisolone Acetate 4
Maropitant Citrate 4
Robenacoxib 4
Oclacitinib Maleate 4
Butorphanol 4
Dexmedetomidine 4
Melarsomine Dihydrochloride Injection 3
Clindamycin 3
Prednisone 3
Anesthetic 3
Buprenorphine 3
Lotilaner 3
Bordetella Vaccine 3

Injection site panniculitis Reaction Insights

100 reports name Injection site panniculitis; 2 recorded a death outcome (2.0% of reported events, not a population-level mortality rate). VeDDRA code: 1053.

By species: Dog (82 reports), Cat (17 reports), Mouse (1 reports). By breed: Retriever - Golden (10), Domestic Shorthair (9), Chihuahua (7).

Most co-reported drugs: Moxidectin (37 reports), Carprofen (14 reports), Cefovecin (12 reports), Melarsomine Dihydrochloride (10 reports).

Read these counts as reporting volume, not risk: per our methodology, co-reporting reflects temporal association captured in voluntary submissions, not proof that a drug caused this reaction. A widely-prescribed drug will rack up more raw co-reports at an identical true rate than a rarely-used one, so compare within similar-exposure products.

Source: FDA Center for Veterinary Medicine openFDA Animal & Veterinary Adverse Events (CVM AER) · 2025

Every figure on PlainBreed is rendered directly from FDA openFDA adverse event data, no number is typed in by an editor. This page draws directly on FDA openFDA data, no figure is typed in by an editor. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.