Reaction profile

The FDA adverse-event record for injection site panniculitis

106 FDA adverse-event reports reference injection site panniculitis (VeDDRA 1053). Plate codes and volume neighbourhood below; species, breeds, and drugs follow.

#1361 of 2,481
by report volume (all reactions)
106
reports citing this reaction
2.8%
death-coded share
Dog
most-affected species

Release-over-release change

What changed in the latest FDA data snapshot

PlainBreed reconstructed the prior snapshot from dated openFDA partitions through 2025 Q4, then compared it with the 2026-07-27 openFDA export. Injection site panniculitis has 106 reports now versus 105 in that prior snapshot: 1 more (1.0%).

Report change
+1
Death-coded reports
+0
Death-coded share
−0.0 pts

This compares reported-event counts in two source snapshots. It does not establish a change in real-world risk, product safety, or disease incidence.

Subscribe to Injection site panniculitis changes

FDA AER · VeDDRA plate

Code 1053 VOL-LOW

VOL-LOW · DEATH-LOW · MID-PACK · PHOTO-FINISH · SPECIES-DOG · DRUG-LEAD · DESK-WIDE · BOOK-FULL

  • VOL-LOW 106 reports
  • DEATH-LOW 2.8%
  • MID-PACK #1361/2481
  • PHOTO-FINISH Contamination, Insects
  • SPECIES-DOG Dog · 87
  • DRUG-LEAD Moxidectin · 40
  • DESK-WIDE 20 breeds
  • BOOK-FULL 8/8 fields

Nearest volume peer: Contamination, Insects (±0 reports)

Instrument codes from this reaction’s FDA CVM adverse-event extract: volume band, death-coded share, corpus rank, photo-finish peer, lead species, lead drug, breed desk, and book completeness. Not a clinical diagnosis.

Report-volume neighbourhood around Injection site panniculitis

Highest and lowest poles plus nearest volume peers, not a full 2,500-reaction corpus board reprint.

Vomiting · highest174348Contamination, Insects · near106Gall bladder inflamma… · near106Injection site pannic… · thi…106Painful defecation · near106Partial adipsia · near106Urinary tract neoplas… · low…10
FDA AER report volume · neighbourhood around Injection site panniculitis

Injection site panniculitis: low death-coded share in the FDA AER plate

Signature read: Injection site panniculitis's 2.8% death-coded share is among the lowest in the openFDA reaction corpus. Report volume sits in the middle third of the reaction corpus. Death-coded share is lower-third: 3 of 106 reports (2.8% of named reports). Nearest volume peer: Contamination, Insects (±0 reports). Lead species Dog (87). Lead co-reported drug Moxidectin (40).

Read these counts as reporting volume, not risk: per our methodology, Lead co-reported drug Moxidectin appears in filings alongside this reaction; that is association, not causation. Browse the full reactions index or the about page for how PlainBreed frames FDA CVM extracts.

Species Most Affected

Dog 87
Cat 18
Mouse 1

Breeds Most Affected

Retriever - Golden 11
Domestic Shorthair 9
Chihuahua 7
Dachshund (unspecified) 7
Maltese 5
Domestic Longhair 4
Terrier - Boston 4
Boxer (German Boxer) 4
Crossbred Canine/dog 4
Great Pyrenees 3

Associated Drugs

Moxidectin 40
Carprofen 14
Cefovecin 12
Melarsomine Dihydrochloride 10
Meloxicam 9
Robenacoxib 5
Butorphanol 5
Dexmedetomidine 5
Rabies Vaccine, Killed Virus 4
Enrofloxacin 4
Methylprednisolone Acetate 4
Maropitant Citrate 4
Oclacitinib Maleate 4
Melarsomine Dihydrochloride Injection 3
Clindamycin 3
Prednisone 3
Anesthetic 3
Buprenorphine 3
Lotilaner 3
Bordetella Vaccine 3

Nationwide reactions with similar profiles

Two openFDA-derived peer sets for Injection site panniculitis, both floored at ≥50 reports so the neighborhoods stay in the advertised mass (the volume chart above is the unfloored photo-finish strip).

Similar report volume

Nearest other reactions by FDA report count (106 here).

Similar death-coded share

Nearest other reactions by death-coded share (2.8% here), distinct from the volume row.

What to do with this reaction

A report does not prove a drug caused the reaction; consult a veterinarian before acting on this data.

Source: FDA Center for Veterinary Medicine openFDA Animal & Veterinary Adverse Events (CVM AER) · 2025

openFDA Animal & Veterinary Adverse Events (FDA CVM) for Injection site panniculitis (#1361 of 2,481 by report volume); death-coded 2.8%. PlainBreed reaction plate · death-coded share stamp 2.8% · vintage 2025.

Informational only. FDA adverse-event reports are voluntary and do not prove causation; consult a veterinarian before acting on them. Verify with FDA CVM →