Haemorrhagic bladder

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VeDDRA Code: 730

21 adverse event reports referencing this reaction

21
Total Reports
10
Deaths
4760.0%
Death Rate

Species Most Affected

Dog 13
Cat 8

Breeds Most Affected

Domestic Shorthair 5
Domestic Longhair 2
Shepherd Dog - Australian 2
Boxer (German Boxer) 2
Retriever - Golden 1
Pekingese 1
Papillon - Spaniel - Continental Toy (with erect ears or with dropped ears (Phaléne)) 1
Pit Bull 1
Doberman Pinscher 1
Retriever - Labrador 1

Associated Drugs

Gabapentin 6
Leptospira-Canicola-Grippotyphosa-Icterohaemorrhagiae-Pomona Bacterial Extract 4
Ketamine 3
Deracoxib 3
Frunevetmab 3
Milbemycin Oxime + Spinosad 2
Cefovecin 2
Anesthetic 2
Robenacoxib 2
Acepromazine 2
Fentanyl 2
Meloxicam 2
Cyclosporine 2
Canine Distemper-Adenovirus Type 2-Parainfluenza-Parvovirus Vaccine, Modified Live Virus 2
Prednisone 2
Methimazole 2
Onsior 2
Ondansetron 2
Carprofen 2
Ilunocitinib 2

Data Summary

Metric Value
Total reports referencing reaction 21
Reports with fatal outcome 10
Case-fatality rate (reported events) 4760.0%
Species observed 2
Breeds observed 14
Drugs associated with reaction 20

Source: FDA Center for Veterinary Medicine — Adverse Event Reporting (CVM AER); reaction term coded under VeDDRA 730.

Haemorrhagic bladder Reaction Insights

The FDA Center for Veterinary Medicine database currently lists 21 adverse event reports that reference Haemorrhagic bladder as a reaction term, including 10 reports with a death outcome — a 4760.0% case-fatality figure calculated across only those events where this reaction was coded. The reaction is indexed in the openFDA system under VeDDRA code 730, the standardized veterinary dictionary used to normalize clinical signs across submitters. Because reports are voluntary and often describe multiple concurrent signs per animal, the volume here reflects reporting intensity rather than true incidence in the broader pet population.

Haemorrhagic bladder appears most frequently in reports for Dog (13 reports), Cat (8 reports) — with Dog dominating at 13 entries. Within those species, the breeds most often named alongside this reaction are Domestic Shorthair (5), Domestic Longhair (2), Shepherd Dog - Australian (2). These distributions are influenced both by underlying breed popularity and by how veterinarians and owners code a given clinical sign, so they should be interpreted as a reporting fingerprint rather than a pure susceptibility ranking.

The drugs most commonly co-reported with Haemorrhagic bladder are Gabapentin (6 reports), Leptospira-Canicola-Grippotyphosa-Icterohaemorrhagiae-Pomona Bacterial Extract (4 reports), Ketamine (3 reports), Deracoxib (3 reports), with Gabapentin appearing alongside this reaction in 6 submissions. Co-reporting does not establish that any specific product caused the reaction — FDA CVM data captures temporal association only. The value of these aggregates is in flagging which therapeutic classes appear repeatedly alongside a given clinical sign, so owners and veterinarians can ask targeted questions about medications currently in use.

Source: FDA Center for Veterinary Medicine — Adverse Event Reports FDA Center for Veterinary Medicine — Adverse Event Reports Data reflects voluntary submissions and may not represent actual incidence rates

Related

Data sourced from official AKC, AVMA, ACVO, and breed-club veterinary references. See our methodology for details. Retrieved and formatted by PlainBreed Editorial