Reaction profile

The FDA adverse-event record for vaginal prolapse

31 FDA reports name vaginal prolapse, a lower-volume reaction in the CVM extract (VeDDRA 819). Plate stamps and neighbourhood peers follow.

#1989 of 2,481
by report volume (all reactions)
31
reports citing this reaction
45.2%
death-coded share
Cattle
most-affected species

Release-over-release change

What changed in the latest FDA data snapshot

PlainBreed reconstructed the prior snapshot from dated openFDA partitions through 2025 Q4, then compared it with the 2026-07-27 openFDA export. Vaginal prolapse has 31 reports now versus 31 in that prior snapshot: 0 the same number of (0.0%).

Report change
+0
Death-coded reports
+0
Death-coded share
−0.0 pts

This compares reported-event counts in two source snapshots. It does not establish a change in real-world risk, product safety, or disease incidence.

Subscribe to Vaginal prolapse changes

FDA AER · VeDDRA plate

Code 819 VOL-TRACE

VOL-TRACE · DEATH-HOT · LOWER-Q · PHOTO-FINISH · SPECIES-CATTLE · DRUG-LEAD · DESK-WIDE · BOOK-FULL

  • VOL-TRACE 31 reports
  • DEATH-HOT 45.2%
  • LOWER-Q #1989/2481
  • PHOTO-FINISH ABNORMAL TEST RESULT,…
  • SPECIES-CATTLE Cattle · 27
  • DRUG-LEAD Progesterone · 8
  • DESK-WIDE 9 breeds
  • BOOK-FULL 8/8 fields

Nearest volume peer: ABNORMAL TEST RESULT, THYROID NOS (±0 reports)

Upper-third death-coded share drives the outcome stamps on this plate; volume band, corpus rank, and co-report peers follow. Not a clinical diagnosis.

Lower-volume neighbourhood around Vaginal prolapse

Lower-third volume poles plus nearest peers, not a full reaction corpus board reprint.

Vomiting · highest174348ABNORMAL TEST RESULT,… · near31ALBUMIN HIGH, URINE · near31BILE ACIDS ABNORMAL,… · near31Clonic seizure · near31Vaginal prolapse · this reac…31Urinary tract neoplas… · low…10
FDA AER report volume · neighbourhood around Vaginal prolapse

Vaginal prolapse: high death-coded share in the FDA AER plate

Signature read: Vaginal prolapse's 45.2% death-coded share is among the highest in the openFDA reaction corpus. Report volume is lower-third scale: 31 named reports in the openFDA extract. Death-coded share is upper-third: 14 of 31 reports (45.2% of named reports). Nearest volume peer: ABNORMAL TEST RESULT, THYROID NOS (±0 reports). Lead species Cattle (27). Lead co-reported drug Progesterone (8).

Read these counts as reporting volume, not risk: per our methodology, A high death-coded share in FDA filings does not prove causation; co-reporting is voluntary temporal association only. Browse the full reactions index or the about page for how PlainBreed frames FDA CVM extracts.

Species Most Affected

Cattle 27
Dog 2
Horse 1
Sheep 1

Breeds Most Affected

Mixed (Cattle) 12
Crossbred Bovine/Cattle 6
Aberdeen Angus 4
Cattle (other) 4
Quarter Horse 1
Crossbred Ovine/sheep 1
Terrier - Irish Soft-coated Wheaten 1
Spitz - German Pomeranian 1
Cattle (unknown) 1

Associated Drugs

Progesterone 8
Melengestrol Acetate 7
Testosterone Propionate;Estradiol Benzoate 4
Trenbolone Acetate;Estradiol Benzoate 4
Monensin Sodium 4
Tylosin Phosphate 4
Lubabegron 3
Estradiol, Testosterone 2
Estradiol Benzoate; Testosterone Propionate 2
Progesterone;Estradiol Benzoate 2
Estradiol Benzoate, Progesterone 1
Progesterone, Estradiol Benzoate, Tylosin Tartrate 1
Pergolide Mesylate 1
Zeranol 1
Estriol Tablets 1
Milbemycin Oxime + Spinosad 1
Nitenpyram 1
Estradiol Benzoate; Trenbolone Acetate 1
Progesterone; Estradiol Benzoate; Tylosin Tartrate 1
Bovine Rhinotracheitis Virus + Virus Diarrhea + Parainfluenza 3 + Respiratory Syncytial Virus + Mannheimia Haemolytica + Pasteurella Multocida Vaccine 1

What to do with this reaction

A report does not prove a drug caused the reaction; consult a veterinarian before acting on this data.

Source: FDA Center for Veterinary Medicine openFDA Animal & Veterinary Adverse Events (CVM AER) · 2025

openFDA Animal & Veterinary Adverse Events (FDA CVM) for Vaginal prolapse (#1989 of 2,481 by report volume); death-coded 45.2%. PlainBreed reaction plate · death-coded share stamp 45.2% · vintage 2025.

Informational only. FDA adverse-event reports are voluntary and do not prove causation; consult a veterinarian before acting on them. Verify with FDA CVM →