Reaction profile

The FDA adverse-event record for loss of voice

33 FDA adverse-event reports reference loss of voice (VeDDRA 1267). See the species, breeds, and drugs most associated with it below.

33
reports citing this reaction
27.3%
death-coded share
Cat
most-affected species
Supplement
most-associated drug
Verify with FDA CVM →
33
Total Reports
9
Deaths
27.3%
Death Rate

Species Most Affected

Cat 16
Dog 14
Human 2
Turkey 1

Breeds Most Affected

Domestic Shorthair 12
Unknown 2
Retriever - Labrador 2
Chihuahua 2
Himalayan 1
Chow Chow 1
Cat (unknown) 1
Domestic Mediumhair 1
Terrier - Yorkshire 1
Dog (unknown) 1

Associated Drugs

Supplement 3
Afoxolaner 3
Frunevetmab 3
Spinosad 2
Maropitant Citrate 2
Thiamazole 2
Imidacloprid + Moxidectin 2
Verdinexor 2
Bedinvetmab 2
Tilmicosin Phosphate 1
Tresaderm Dermatological Solution 1
Glucosamine 1
Heartworm Prevention (Unknown) 1
Cyclosporine A 1
Febantel + Praziquantel + Pyrantel Pamoate 1
Vitamin 1
Veterinary Diet 1
Probiotic 1
Lysine 1
Prednisolone 1

Loss of voice Reaction Insights

33 reports name Loss of voice; 9 recorded a death outcome (27.3% of reported events, not a population-level mortality rate). VeDDRA code: 1267.

By species: Cat (16 reports), Dog (14 reports), Human (2 reports). By breed: Domestic Shorthair (12), Unknown (2), Retriever - Labrador (2).

Most co-reported drugs: Supplement (3 reports), Afoxolaner (3 reports), Frunevetmab (3 reports), Spinosad (2 reports).

Read these counts as reporting volume, not risk: per our methodology, co-reporting reflects temporal association captured in voluntary submissions, not proof that a drug caused this reaction. A widely-prescribed drug will rack up more raw co-reports at an identical true rate than a rarely-used one, so compare within similar-exposure products.

Source: FDA Center for Veterinary Medicine openFDA Animal & Veterinary Adverse Events (CVM AER) · 2025

Every figure on PlainBreed is rendered directly from FDA openFDA adverse event data, no number is typed in by an editor. This page draws directly on FDA openFDA data, no figure is typed in by an editor. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.