Reaction profile

The FDA adverse-event record for loss of voice

Name: Loss of voice - FDA Animal Adverse Reaction
Creator: PlainBreed
License: https://open.fda.gov/license/

35 FDA reports name loss of voice, a lower-volume reaction in the CVM extract (VeDDRA 1267). Plate stamps and neighbourhood peers follow.

#1922 of 2,481
by report volume (all reactions): 35
reports citing this reaction: 28.6%
death-coded share: Cat
most-affected species

Compiled by PlainBreed

Verify with FDA CVM →

Release-over-release change

What changed in the latest FDA data snapshot

PlainBreed reconstructed the prior snapshot from dated openFDA partitions through 2025 Q4, then compared it with the 2026-07-27 openFDA export. Loss of voice has 35 reports now versus 34 in that prior snapshot: 1 more (2.9%).

Report change: +1
Death-coded reports: +1
Death-coded share: +2.1 pts

This compares reported-event counts in two source snapshots. It does not establish a change in real-world risk, product safety, or disease incidence.

Subscribe to Loss of voice changes

FDA AER · VeDDRA plate

Code 1267 VOL-TRACE

VOL-TRACE · DEATH-HOT · LOWER-Q · PHOTO-FINISH · SPECIES-CAT · DRUG-LEAD · DESK-WIDE · BOOK-FULL

VOL-TRACE 35 reports
DEATH-HOT 28.6%
LOWER-Q #1922/2481
PHOTO-FINISH CARBON DIOXIDE LOW, B…
SPECIES-CAT Cat · 16
DRUG-LEAD Supplement · 3
DESK-WIDE 20 breeds
BOOK-FULL 8/8 fields

Nearest volume peer: CARBON DIOXIDE LOW, BLOOD (±0 reports)

Upper-third death-coded share drives the outcome stamps on this plate; volume band, corpus rank, and co-report peers follow. Not a clinical diagnosis.

Lower-volume neighbourhood around Loss of voice

Lower-third volume poles plus nearest peers, not a full reaction corpus board reprint.

FDA AER report volume · neighbourhood around Loss of voice

Loss of voice: high death-coded share in the FDA AER plate

Signature read: 35 reports place Loss of voice in the lower third of FDA AER volume (#1922 of 2,481). Report volume is lower-third scale: 35 named reports in the openFDA extract. Death-coded share is upper-third: 10 of 35 reports (28.6% of named reports). Nearest volume peer: CARBON DIOXIDE LOW, BLOOD (±0 reports). Lead species Cat (16). Lead co-reported drug Supplement (3).

Read these counts as reporting volume, not risk: per our methodology, A high death-coded share in FDA filings does not prove causation; co-reporting is voluntary temporal association only. Browse the full reactions index or the about page for how PlainBreed frames FDA CVM extracts.

Species Most Affected

Cat 16

Dog 16

Human 2

Turkey 1

Breeds Most Affected

Domestic Shorthair 12

Unknown 2

Retriever - Labrador 2

Chihuahua 2

Himalayan 1

Chow Chow 1

Cat (unknown) 1

Domestic Mediumhair 1

Terrier - Yorkshire 1

Dog (unknown) 1

Associated Drugs

Supplement 3

Afoxolaner 3

Bedinvetmab 3

Frunevetmab 3

Spinosad 2

Maropitant Citrate 2

Thiamazole 2

Imidacloprid + Moxidectin 2

Verdinexor 2

Tilmicosin Phosphate 1

Tresaderm Dermatological Solution 1

Glucosamine 1

Heartworm Prevention (Unknown) 1

Cyclosporine A 1

Febantel + Praziquantel + Pyrantel Pamoate 1

Vitamin 1

Veterinary Diet 1

Probiotic 1

Lysine 1

Prednisolone 1

What to do with this reaction

Read how death-coded share differs from a mortality rate before drawing conclusions. Understanding adverse events
Browse the full reaction directory to compare report counts across reaction types. All reactions

A report does not prove a drug caused the reaction; consult a veterinarian before acting on this data.

Source: FDA Center for Veterinary Medicine openFDA Animal & Veterinary Adverse Events (CVM AER) · 2025

openFDA Animal & Veterinary Adverse Events (FDA CVM) for Loss of voice (#1922 of 2,481 by report volume); death-coded 28.6%. PlainBreed reaction plate · report volume stamp 35 · vintage 2025.

Informational only. FDA adverse-event reports are voluntary and do not prove causation; consult a veterinarian before acting on them. Verify with FDA CVM →