INEFFECTIVE, ANALGESIA

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VeDDRA Code: 99081

211 adverse event reports referencing this reaction

211
Total Reports
9
Deaths
430.0%
Death Rate

Species Most Affected

Dog 116
Cat 78
Horse 13
Other Camelids 1
Unknown 1
Pig 1
Mouse 1

Breeds Most Affected

Cat (unknown) 62
Crossbred Canine/dog 18
Retriever - Labrador 16
Dog (unknown) 11
Domestic (unspecified) 7
Shepherd Dog - German 6
Retriever - Golden 4
Poodle (unspecified) 4
Horse (unknown) 4
Domestic Shorthair 4

Associated Drugs

Robenacoxib 68
Unknown Whether Concomitant Medications Other Than Anesthetic Protocol 59
Carprofen 52
Meloxicam 35
Deracoxib 20
Butorphanol Tartrate 9
Firocoxib 7
Grapiprant 6
Milbemycin Oxime + Praziquantel 6
Gabapentin 4
Polysulfated Glycosaminoglycan 4
Detomidine Hydrochloride 4
Tramadol 3
Isoflurane 3
Flunixin Meglumine Injectable 3
Dexmedetomidine Hydrochloride 2
Methocarbamol 2
Buprenorphine 2
Glucosamine + Chondroitin 2
N-Butylscopolaminium Bromide 2

Data Summary

Metric Value
Total reports referencing reaction 211
Reports with fatal outcome 9
Case-fatality rate (reported events) 430.0%
Species observed 7
Breeds observed 20
Drugs associated with reaction 20

Source: FDA Center for Veterinary Medicine — Adverse Event Reporting (CVM AER); reaction term coded under VeDDRA 99081.

INEFFECTIVE, ANALGESIA Reaction Insights

The FDA Center for Veterinary Medicine database currently lists 211 adverse event reports that reference INEFFECTIVE, ANALGESIA as a reaction term, including 9 reports with a death outcome — a 430.0% case-fatality figure calculated across only those events where this reaction was coded. The reaction is indexed in the openFDA system under VeDDRA code 99081, the standardized veterinary dictionary used to normalize clinical signs across submitters. Because reports are voluntary and often describe multiple concurrent signs per animal, the volume here reflects reporting intensity rather than true incidence in the broader pet population.

INEFFECTIVE, ANALGESIA appears most frequently in reports for Dog (116 reports), Cat (78 reports), Horse (13 reports) — with Dog dominating at 116 entries. Within those species, the breeds most often named alongside this reaction are Cat (unknown) (62), Crossbred Canine/dog (18), Retriever - Labrador (16). These distributions are influenced both by underlying breed popularity and by how veterinarians and owners code a given clinical sign, so they should be interpreted as a reporting fingerprint rather than a pure susceptibility ranking.

The drugs most commonly co-reported with INEFFECTIVE, ANALGESIA are Robenacoxib (68 reports), Unknown Whether Concomitant Medications Other Than Anesthetic Protocol (59 reports), Carprofen (52 reports), Meloxicam (35 reports), with Robenacoxib appearing alongside this reaction in 68 submissions. Co-reporting does not establish that any specific product caused the reaction — FDA CVM data captures temporal association only. The value of these aggregates is in flagging which therapeutic classes appear repeatedly alongside a given clinical sign, so owners and veterinarians can ask targeted questions about medications currently in use.

Source: FDA Center for Veterinary Medicine — Adverse Event Reports FDA Center for Veterinary Medicine — Adverse Event Reports Data reflects voluntary submissions and may not represent actual incidence rates

Related

Data sourced from official AKC, AVMA, ACVO, and breed-club veterinary references. See our methodology for details. Retrieved and formatted by PlainBreed Editorial