Reaction profile

The FDA adverse-event record for ineffective, analgesia

211 FDA adverse-event reports reference ineffective, analgesia (VeDDRA 99081). See the species, breeds, and drugs most associated with it below.

211
reports citing this reaction
4.3%
death-coded share
Dog
most-affected species
Robenacoxib
most-associated drug
Verify with FDA CVM →
211
Total Reports
9
Deaths
4.3%
Death Rate

Species Most Affected

Dog 116
Cat 78
Horse 13
Other Camelids 1
Unknown 1
Pig 1
Mouse 1

Breeds Most Affected

Cat (unknown) 62
Crossbred Canine/dog 18
Retriever - Labrador 16
Dog (unknown) 11
Domestic (unspecified) 7
Shepherd Dog - German 6
Retriever - Golden 4
Poodle (unspecified) 4
Horse (unknown) 4
Domestic Shorthair 4

Associated Drugs

Robenacoxib 68
Unknown Whether Concomitant Medications Other Than Anesthetic Protocol 59
Carprofen 52
Meloxicam 35
Deracoxib 20
Butorphanol Tartrate 9
Firocoxib 7
Grapiprant 6
Milbemycin Oxime + Praziquantel 6
Gabapentin 4
Polysulfated Glycosaminoglycan 4
Detomidine Hydrochloride 4
Tramadol 3
Isoflurane 3
Flunixin Meglumine Injectable 3
Dexmedetomidine Hydrochloride 2
Methocarbamol 2
Buprenorphine 2
Glucosamine + Chondroitin 2
N-Butylscopolaminium Bromide 2

INEFFECTIVE, ANALGESIA Reaction Insights

211 reports name INEFFECTIVE, ANALGESIA; 9 recorded a death outcome (4.3% of reported events, not a population-level mortality rate). VeDDRA code: 99081.

By species: Dog (116 reports), Cat (78 reports), Horse (13 reports). By breed: Cat (unknown) (62), Crossbred Canine/dog (18), Retriever - Labrador (16).

Most co-reported drugs: Robenacoxib (68 reports), Unknown Whether Concomitant Medications Other Than Anesthetic Protocol (59 reports), Carprofen (52 reports), Meloxicam (35 reports).

Read these counts as reporting volume, not risk: per our methodology, co-reporting reflects temporal association captured in voluntary submissions, not proof that a drug caused this reaction. A widely-prescribed drug will rack up more raw co-reports at an identical true rate than a rarely-used one, so compare within similar-exposure products.

Source: FDA Center for Veterinary Medicine openFDA Animal & Veterinary Adverse Events (CVM AER) · 2025

Every figure on PlainBreed is rendered directly from FDA openFDA adverse event data, no number is typed in by an editor. This page draws directly on FDA openFDA data, no figure is typed in by an editor. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.