Reaction profile

The FDA adverse-event record for ventricular arrhythmia

136 FDA adverse-event reports reference ventricular arrhythmia (VeDDRA 2222). See the species, breeds, and drugs most associated with it below.

136
reports citing this reaction
37.5%
death-coded share
Dog
most-affected species
Dexmedetomidine Hydrochloride
most-associated drug
Verify with FDA CVM →
136
Total Reports
51
Deaths
37.5%
Death Rate

Species Most Affected

Dog 125
Cat 9
Other Rodents 1
Rabbit 1

Breeds Most Affected

Retriever - Labrador 25
Shepherd Dog - German 6
Crossbred Canine/dog 6
Boxer (German Boxer) 6
Doberman Pinscher 6
Retriever - Golden 6
Greyhound 5
Terrier - Bull - American Pit 5
Domestic Shorthair 5
Chihuahua 4

Associated Drugs

Dexmedetomidine Hydrochloride 20
Maropitant Citrate 16
Carprofen 15
Isoflurane 13
Moxidectin 12
Propofol 9
Butorphanol 8
Bedinvetmab 8
Oclacitinib Maleate 7
Meloxicam 7
Hydromorphone 7
Lidocaine 7
Deracoxib 6
Melarsomine Dihydrochloride Injection 6
Midazolam 6
Buprenorphine 6
Epinephrine 6
Melarsomine Dihydrochloride 6
Dexmedetomidine 6
Ivermectin + Pyrantel As Pamoate Salt 5

Ventricular arrhythmia Reaction Insights

136 reports name Ventricular arrhythmia; 51 recorded a death outcome (37.5% of reported events, not a population-level mortality rate). VeDDRA code: 2222.

By species: Dog (125 reports), Cat (9 reports), Other Rodents (1 reports). By breed: Retriever - Labrador (25), Shepherd Dog - German (6), Crossbred Canine/dog (6).

Most co-reported drugs: Dexmedetomidine Hydrochloride (20 reports), Maropitant Citrate (16 reports), Carprofen (15 reports), Isoflurane (13 reports).

Read these counts as reporting volume, not risk: per our methodology, co-reporting reflects temporal association captured in voluntary submissions, not proof that a drug caused this reaction. A widely-prescribed drug will rack up more raw co-reports at an identical true rate than a rarely-used one, so compare within similar-exposure products.

Source: FDA Center for Veterinary Medicine openFDA Animal & Veterinary Adverse Events (CVM AER) · 2025

Every figure on PlainBreed is rendered directly from FDA openFDA adverse event data, no number is typed in by an editor. This page draws directly on FDA openFDA data, no figure is typed in by an editor. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.