Reaction profile

The FDA adverse-event record for lipaemia

329 FDA adverse-event reports reference lipaemia (VeDDRA 2421). Plate codes and volume neighbourhood below; species, breeds, and drugs follow.

#835 of 2,481
by report volume (all reactions)
329
reports citing this reaction
13.1%
death-coded share
Dog
most-affected species

Release-over-release change

What changed in the latest FDA data snapshot

PlainBreed reconstructed the prior snapshot from dated openFDA partitions through 2025 Q4, then compared it with the 2026-07-27 openFDA export. Lipaemia has 329 reports now versus 317 in that prior snapshot: 12 more (3.8%).

Report change
+12
Death-coded reports
+2
Death-coded share
+0.1 pts

This compares reported-event counts in two source snapshots. It does not establish a change in real-world risk, product safety, or disease incidence.

Subscribe to Lipaemia changes

FDA AER · VeDDRA plate

Code 2421 VOL-LOW

VOL-LOW · DEATH-ELEV · MID-PACK · PHOTO-FINISH · SPECIES-DOG · DRUG-LEAD · DESK-WIDE · BOOK-FULL

  • VOL-LOW 329 reports
  • DEATH-ELEV 13.1%
  • MID-PACK #835/2481
  • PHOTO-FINISH Hepatic disorder NOS
  • SPECIES-DOG Dog · 285
  • DRUG-LEAD Trilostane · 178
  • DESK-WIDE 20 breeds
  • BOOK-FULL 8/8 fields

Nearest volume peer: Hepatic disorder NOS (±0 reports)

Instrument codes from this reaction’s FDA CVM adverse-event extract: volume band, death-coded share, corpus rank, photo-finish peer, lead species, lead drug, breed desk, and book completeness. Not a clinical diagnosis.

Report-volume neighbourhood around Lipaemia

Highest and lowest poles plus nearest volume peers, not a full 2,500-reaction corpus board reprint.

Vomiting · highest174348Circling - behavioura… · near333Hepatic disorder NOS · near329Lipaemia · this reaction329Ear canal erythema · near328Irregular breathing · near326Urinary tract neoplas… · low…10
FDA AER report volume · neighbourhood around Lipaemia

What the FDA AER plate says about Lipaemia

Signature read: 43 death-coded reports is a heavy tail count for Lipaemia in the CVM extract. Report volume sits in the middle third of the reaction corpus. 43 of 329 reports were death-coded (13.1% of named reports, not a population mortality rate). Nearest volume peer: Hepatic disorder NOS (±0 reports). Lead species Dog (285). Lead co-reported drug Trilostane (178).

Read these counts as reporting volume, not risk: per our methodology, Lead co-reported drug Trilostane appears in filings alongside this reaction; that is association, not causation. Browse the full reactions index or the about page for how PlainBreed frames FDA CVM extracts.

Species Most Affected

Dog 285
Cat 43
Horse 1

Breeds Most Affected

Domestic Shorthair 25
Retriever - Labrador 21
Crossbred Canine/dog 20
Chihuahua 20
Terrier - Yorkshire 19
Maltese 13
Shih Tzu 13
Schnauzer (unspecified) 10
Beagle 10
Dachshund - Standard Long-haired 9

Associated Drugs

Trilostane 178
Milbemycin Oxime + Spinosad 25
Prednisone 22
Carprofen 19
Oclacitinib Maleate 17
Insulin 16
Bexagliflozin 15
Insulin Injectable Vial 14
Maropitant Citrate 13
Desoxycorticosterone Pivalate 12
Moxidectin 11
Phenylpropanolamine 11
Gabapentin 11
Spinosad 9
Velagliflozin Proline Monohydrate 9
Enalapril 8
Ursodiol 7
Fluralaner Chew Tablets 7
Bedinvetmab 7
Afoxolaner 6

Nationwide reactions with similar profiles

Two openFDA-derived peer sets for Lipaemia, both floored at ≥50 reports so the neighborhoods stay in the advertised mass (the volume chart above is the unfloored photo-finish strip).

Similar death-coded share

Nearest other reactions by death-coded share (13.1% here), distinct from the volume row.

What to do with this reaction

A report does not prove a drug caused the reaction; consult a veterinarian before acting on this data.

Source: FDA Center for Veterinary Medicine openFDA Animal & Veterinary Adverse Events (CVM AER) · 2025

openFDA Animal & Veterinary Adverse Events (FDA CVM) for Lipaemia (#835 of 2,481 by report volume); death-coded 13.1%. PlainBreed reaction plate · death-coded report count stamp 43 · vintage 2025.

Informational only. FDA adverse-event reports are voluntary and do not prove causation; consult a veterinarian before acting on them. Verify with FDA CVM →