Reaction profile

The FDA adverse-event record for tympanic rupture

237 FDA adverse-event reports reference tympanic rupture (VeDDRA 2386). Plate codes and volume neighbourhood below; species, breeds, and drugs follow.

#964 of 2,481
by report volume (all reactions)
237
reports citing this reaction
3.4%
death-coded share
Dog
most-affected species

Release-over-release change

What changed in the latest FDA data snapshot

PlainBreed reconstructed the prior snapshot from dated openFDA partitions through 2025 Q4, then compared it with the 2026-07-27 openFDA export. Tympanic rupture has 237 reports now versus 230 in that prior snapshot: 7 more (3.0%).

Report change
+7
Death-coded reports
+0
Death-coded share
−0.1 pts

This compares reported-event counts in two source snapshots. It does not establish a change in real-world risk, product safety, or disease incidence.

Subscribe to Tympanic rupture changes

FDA AER · VeDDRA plate

Code 2386 VOL-LOW

VOL-LOW · DEATH-LOW · MID-PACK · PHOTO-FINISH · SPECIES-DOG · DRUG-LEAD · DESK-WIDE · BOOK-FULL

  • VOL-LOW 237 reports
  • DEATH-LOW 3.4%
  • MID-PACK #964/2481
  • PHOTO-FINISH Blinking
  • SPECIES-DOG Dog · 175
  • DRUG-LEAD Florfenicol + Mom… · 101
  • DESK-WIDE 20 breeds
  • BOOK-FULL 8/8 fields

Nearest volume peer: Blinking (±0 reports)

Instrument codes from this reaction’s FDA CVM adverse-event extract: volume band, death-coded share, corpus rank, photo-finish peer, lead species, lead drug, breed desk, and book completeness. Not a clinical diagnosis.

Report-volume neighbourhood around Tympanic rupture

Highest and lowest poles plus nearest volume peers, not a full 2,500-reaction corpus board reprint.

Vomiting · highest174348Drug schedule prescri… · near238Increased sweating · near238Blinking · near237Torn ligament · near237Tympanic rupture · this reac…237Urinary tract neoplas… · low…10
FDA AER report volume · neighbourhood around Tympanic rupture

Tympanic rupture: low death-coded share in the FDA AER plate

Signature read: Tympanic rupture's 3.4% death-coded share is among the lowest in the openFDA reaction corpus. Report volume sits in the middle third of the reaction corpus. Death-coded share is lower-third: 8 of 237 reports (3.4% of named reports). Nearest volume peer: Blinking (±0 reports). Lead species Dog (175). Lead co-reported drug Florfenicol + Mometasone Furoate + Terbinafine Hydrochloride (101).

Read these counts as reporting volume, not risk: per our methodology, Lead co-reported drug Florfenicol + Mometasone Furoate + Terbinafine Hydrochloride appears in filings alongside this reaction; that is association, not causation. Browse the full reactions index or the about page for how PlainBreed frames FDA CVM extracts.

Species Most Affected

Dog 175
Cat 62

Breeds Most Affected

Domestic Shorthair 36
Retriever - Labrador 12
Crossbred Canine/dog 10
Bulldog - French 10
Shih Tzu 9
Chihuahua 9
Domestic Longhair 7
Terrier (unspecified) 7
Terrier - Yorkshire 6
Pit Bull 5

Associated Drugs

Florfenicol + Mometasone Furoate + Terbinafine Hydrochloride 101
Maropitant Citrate 37
Prednisone 20
Genta/Momet/Clotrim Ear Oint 19
Florfenicol/Terbinafine Hydrochloride/Mometasone Furoate 18
Florfenicol, Terbinafine, Betamethasone Acetate 18
Carprofen 17
Gabapentin 16
Saline 14
Enrofloxacin 14
Orbiflox/Momet/Posaco Eardrops 14
Ear Cleaner 14
Ear Cleaner (Unknown) 13
Betamethasone + Florfenicol + Terbinafine 10
Cefpodoxime 10
Florfenicol + Mometasone Furoate + Terbinafine 10
Dexamethasone 9
Oclacitinib Maleate 9
Salicylic Acid 9
Diphenhydramine 8

Nationwide reactions with similar profiles

Two openFDA-derived peer sets for Tympanic rupture, both floored at ≥50 reports so the neighborhoods stay in the advertised mass (the volume chart above is the unfloored photo-finish strip).

Similar report volume

Nearest other reactions by FDA report count (237 here).

Similar death-coded share

Nearest other reactions by death-coded share (3.4% here), distinct from the volume row.

What to do with this reaction

A report does not prove a drug caused the reaction; consult a veterinarian before acting on this data.

Source: FDA Center for Veterinary Medicine openFDA Animal & Veterinary Adverse Events (CVM AER) · 2025

openFDA Animal & Veterinary Adverse Events (FDA CVM) for Tympanic rupture (#964 of 2,481 by report volume); death-coded 3.4%. PlainBreed reaction plate · death-coded share stamp 3.4% · vintage 2025.

Informational only. FDA adverse-event reports are voluntary and do not prove causation; consult a veterinarian before acting on them. Verify with FDA CVM →