Reaction profile

The FDA adverse-event record for potency, low

318 FDA adverse-event reports reference potency, low (VeDDRA 99020). Plate codes and volume neighbourhood below; species, breeds, and drugs follow.

#844 of 2,481
by report volume (all reactions)
318
reports citing this reaction
3.1%
death-coded share
Unknown
most-affected species

Release-over-release change

What changed in the latest FDA data snapshot

PlainBreed reconstructed the prior snapshot from dated openFDA partitions through 2025 Q4, then compared it with the 2026-07-27 openFDA export. Potency, Low has 318 reports now versus 316 in that prior snapshot: 2 more (0.6%).

Report change
+2
Death-coded reports
+0
Death-coded share
−0.0 pts

This compares reported-event counts in two source snapshots. It does not establish a change in real-world risk, product safety, or disease incidence.

Subscribe to Potency, Low changes

FDA AER · VeDDRA plate

Code 99020 VOL-LOW

VOL-LOW · DEATH-LOW · MID-PACK · PHOTO-FINISH · SPECIES-UNKNOWN · DRUG-LEAD · DESK-WIDE · BOOK-FULL

  • VOL-LOW 318 reports
  • DEATH-LOW 3.1%
  • MID-PACK #844/2481
  • PHOTO-FINISH Injection site hair l…
  • SPECIES-UNKNOWN Unknown · 270
  • DRUG-LEAD Virginiamycin · 43
  • DESK-WIDE 20 breeds
  • BOOK-FULL 8/8 fields

Nearest volume peer: Injection site hair loss (±0 reports)

Instrument codes from this reaction’s FDA CVM adverse-event extract: volume band, death-coded share, corpus rank, photo-finish peer, lead species, lead drug, breed desk, and book completeness. Not a clinical diagnosis.

Report-volume neighbourhood around Potency, Low

Highest and lowest poles plus nearest volume peers, not a full 2,500-reaction corpus board reprint.

Vomiting · highest174348Impaired hearing · near321Scale · near321Injection site hair l… · near318Potency, Low · this reaction318Epiphora · near315Urinary tract neoplas… · low…10
FDA AER report volume · neighbourhood around Potency, Low

Potency, Low: low death-coded share in the FDA AER plate

Signature read: Potency, Low's 3.1% death-coded share is among the lowest in the openFDA reaction corpus. Report volume sits in the middle third of the reaction corpus. Death-coded share is lower-third: 10 of 318 reports (3.1% of named reports). Nearest volume peer: Injection site hair loss (±0 reports). Lead species Unknown (270). Lead co-reported drug Virginiamycin (43).

Read these counts as reporting volume, not risk: per our methodology, Lead co-reported drug Virginiamycin appears in filings alongside this reaction; that is association, not causation. Browse the full reactions index or the about page for how PlainBreed frames FDA CVM extracts.

Species Most Affected

Unknown 270
Dog 21
Cattle 10
Horse 7
Cat 3
Other 2
Other Birds 2
Sheep 1
Chicken 1
Pig 1

Breeds Most Affected

Unknown 274
Crossbred Canine/dog 4
Cattle (unknown) 3
Quarter Horse 3
Chihuahua 3
Mixed (Horse) 2
Holstein-Friesian also known as Holstein 2
Aberdeen Angus 2
Domestic Shorthair 2
Dog (unknown) 2

Associated Drugs

Virginiamycin 43
Salinomycin Sodium 30
Amprolium 18
Lasalocid 9
Thiostrepton 9
Clotrimazole + Gentamicin + Mometasone 9
Nystatin 8
Levothyroxine Sodium 6
Nicarbazin 6
Polysulfated Glycosaminoglycan 5
Monensin Sodium 5
Neomycin + Oxytetracycline Anhydrous 5
Chlortetracycline 5
Amprolium Ion 5
Insulin Injectable Vial 5
Penicillin G 5
Pentobarbital Sodium + Phenytoin Sodium 5
Firocoxib 5
Progesterone 4
Dinoprost Tromethamine 4

Nationwide reactions with similar profiles

Two openFDA-derived peer sets for Potency, Low, both floored at ≥50 reports so the neighborhoods stay in the advertised mass (the volume chart above is the unfloored photo-finish strip).

Similar report volume

Nearest other reactions by FDA report count (318 here).

Similar death-coded share

Nearest other reactions by death-coded share (3.1% here), distinct from the volume row.

What to do with this reaction

A report does not prove a drug caused the reaction; consult a veterinarian before acting on this data.

Source: FDA Center for Veterinary Medicine openFDA Animal & Veterinary Adverse Events (CVM AER) · 2025

openFDA Animal & Veterinary Adverse Events (FDA CVM) for Potency, Low (#844 of 2,481 by report volume); death-coded 3.1%. PlainBreed reaction plate · death-coded share stamp 3.1% · vintage 2025.

Informational only. FDA adverse-event reports are voluntary and do not prove causation; consult a veterinarian before acting on them. Verify with FDA CVM →