Potency, Low

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VeDDRA Code: 99020

308 adverse event reports referencing this reaction

308
Total Reports
10
Deaths
320.0%
Death Rate

Species Most Affected

Unknown 262
Dog 19
Cattle 10
Horse 7
Cat 3
Other 2
Other Birds 2
Sheep 1
Chicken 1
Pig 1

Breeds Most Affected

Unknown 266
Crossbred Canine/dog 4
Cattle (unknown) 3
Quarter Horse 3
Mixed (Horse) 2
Holstein-Friesian also known as Holstein 2
Aberdeen Angus 2
Domestic Shorthair 2
Dog (unknown) 2
Chihuahua 2

Associated Drugs

Virginiamycin 43
Salinomycin Sodium 27
Amprolium 16
Lasalocid 9
Thiostrepton 9
Nystatin 8
Clotrimazole + Gentamicin + Mometasone 7
Levothyroxine Sodium 6
Nicarbazin 6
Polysulfated Glycosaminoglycan 5
Monensin Sodium 5
Neomycin + Oxytetracycline Anhydrous 5
Chlortetracycline 5
Amprolium Ion 5
Insulin Injectable Vial 5
Penicillin G 5
Pentobarbital Sodium + Phenytoin Sodium 5
Firocoxib 5
Progesterone 4
Dinoprost Tromethamine 4

Data Summary

Metric Value
Total reports referencing reaction 308
Reports with fatal outcome 10
Case-fatality rate (reported events) 320.0%
Species observed 10
Breeds observed 20
Drugs associated with reaction 20

Source: FDA Center for Veterinary Medicine — Adverse Event Reporting (CVM AER); reaction term coded under VeDDRA 99020.

Potency, Low Reaction Insights

The FDA Center for Veterinary Medicine database currently lists 308 adverse event reports that reference Potency, Low as a reaction term, including 10 reports with a death outcome — a 320.0% case-fatality figure calculated across only those events where this reaction was coded. The reaction is indexed in the openFDA system under VeDDRA code 99020, the standardized veterinary dictionary used to normalize clinical signs across submitters. Because reports are voluntary and often describe multiple concurrent signs per animal, the volume here reflects reporting intensity rather than true incidence in the broader pet population.

Potency, Low appears most frequently in reports for Unknown (262 reports), Dog (19 reports), Cattle (10 reports) — with Unknown dominating at 262 entries. Within those species, the breeds most often named alongside this reaction are Unknown (266), Crossbred Canine/dog (4), Cattle (unknown) (3). These distributions are influenced both by underlying breed popularity and by how veterinarians and owners code a given clinical sign, so they should be interpreted as a reporting fingerprint rather than a pure susceptibility ranking.

The drugs most commonly co-reported with Potency, Low are Virginiamycin (43 reports), Salinomycin Sodium (27 reports), Amprolium (16 reports), Lasalocid (9 reports), with Virginiamycin appearing alongside this reaction in 43 submissions. Co-reporting does not establish that any specific product caused the reaction — FDA CVM data captures temporal association only. The value of these aggregates is in flagging which therapeutic classes appear repeatedly alongside a given clinical sign, so owners and veterinarians can ask targeted questions about medications currently in use.

Source: FDA Center for Veterinary Medicine — Adverse Event Reports FDA Center for Veterinary Medicine — Adverse Event Reports Data reflects voluntary submissions and may not represent actual incidence rates

Related

Data sourced from official AKC, AVMA, ACVO, and breed-club veterinary references. See our methodology for details. Retrieved and formatted by PlainBreed Editorial