Reaction profile

The FDA adverse-event record for potency, low

308 FDA adverse-event reports reference potency, low (VeDDRA 99020). See the species, breeds, and drugs most associated with it below.

308
reports citing this reaction
3.2%
death-coded share
Unknown
most-affected species
Virginiamycin
most-associated drug
Verify with FDA CVM →
308
Total Reports
10
Deaths
3.2%
Death Rate

Species Most Affected

Unknown 262
Dog 19
Cattle 10
Horse 7
Cat 3
Other 2
Other Birds 2
Sheep 1
Chicken 1
Pig 1

Breeds Most Affected

Unknown 266
Crossbred Canine/dog 4
Cattle (unknown) 3
Quarter Horse 3
Mixed (Horse) 2
Holstein-Friesian also known as Holstein 2
Aberdeen Angus 2
Domestic Shorthair 2
Dog (unknown) 2
Chihuahua 2

Associated Drugs

Virginiamycin 43
Salinomycin Sodium 27
Amprolium 16
Lasalocid 9
Thiostrepton 9
Nystatin 8
Clotrimazole + Gentamicin + Mometasone 7
Levothyroxine Sodium 6
Nicarbazin 6
Polysulfated Glycosaminoglycan 5
Monensin Sodium 5
Neomycin + Oxytetracycline Anhydrous 5
Chlortetracycline 5
Amprolium Ion 5
Insulin Injectable Vial 5
Penicillin G 5
Pentobarbital Sodium + Phenytoin Sodium 5
Firocoxib 5
Progesterone 4
Dinoprost Tromethamine 4

Potency, Low Reaction Insights

308 reports name Potency, Low; 10 recorded a death outcome (3.2% of reported events, not a population-level mortality rate). VeDDRA code: 99020.

By species: Unknown (262 reports), Dog (19 reports), Cattle (10 reports). By breed: Unknown (266), Crossbred Canine/dog (4), Cattle (unknown) (3).

Most co-reported drugs: Virginiamycin (43 reports), Salinomycin Sodium (27 reports), Amprolium (16 reports), Lasalocid (9 reports).

Read these counts as reporting volume, not risk: per our methodology, co-reporting reflects temporal association captured in voluntary submissions, not proof that a drug caused this reaction. A widely-prescribed drug will rack up more raw co-reports at an identical true rate than a rarely-used one, so compare within similar-exposure products.

Source: FDA Center for Veterinary Medicine openFDA Animal & Veterinary Adverse Events (CVM AER) · 2025

Every figure on PlainBreed is rendered directly from FDA openFDA adverse event data, no number is typed in by an editor. This page draws directly on FDA openFDA data, no figure is typed in by an editor. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.