Reaction profile

The FDA adverse-event record for elevated triglyceride

711 FDA reports name elevated triglyceride, a high-volume reaction in the CVM extract (VeDDRA 2508). Plate stamps and neighbourhood peers follow.

#507 of 2,481
by report volume (all reactions)
711
reports citing this reaction
14.2%
death-coded share
Dog
most-affected species

Release-over-release change

What changed in the latest FDA data snapshot

PlainBreed reconstructed the prior snapshot from dated openFDA partitions through 2025 Q4, then compared it with the 2026-07-27 openFDA export. Elevated triglyceride has 711 reports now versus 674 in that prior snapshot: 37 more (5.5%).

Report change
+37
Death-coded reports
+4
Death-coded share
−0.2 pts

This compares reported-event counts in two source snapshots. It does not establish a change in real-world risk, product safety, or disease incidence.

Subscribe to Elevated triglyceride changes

FDA AER · VeDDRA plate

Code 2508 VOL-MID

VOL-MID · DEATH-ELEV · UPPER-Q · PHOTO-FINISH · SPECIES-DOG · DRUG-LEAD · DESK-WIDE · BOOK-FULL

  • VOL-MID 711 reports
  • DEATH-ELEV 14.2%
  • UPPER-Q #507/2481
  • PHOTO-FINISH Application site hair…
  • SPECIES-DOG Dog · 555
  • DRUG-LEAD Trilostane · 178
  • DESK-WIDE 20 breeds
  • BOOK-FULL 8/8 fields

Nearest volume peer: Application site hair change (±2 reports)

Upper-third report volume drives the scale stamps on this plate; death-coded share and co-report peers follow. Not a clinical diagnosis.

High-volume neighbourhood around Elevated triglyceride

Upper-third volume poles plus nearest peers, not a full reaction corpus board reprint.

Vomiting · highest174348Localised itching · near718Vomiting bile · near715Elevated triglyceride · this…711Application site hair… · near709Excessive chewing, li… · near704Urinary tract neoplas… · low…10
FDA AER report volume · neighbourhood around Elevated triglyceride

What the FDA AER plate says about Elevated triglyceride

Signature read: 101 death-coded reports is a heavy tail count for Elevated triglyceride in the CVM extract. Report volume is upper-third scale: 711 named reports in the openFDA extract. 101 of 711 reports were death-coded (14.2% of named reports, not a population mortality rate). Nearest volume peer: Application site hair change (±2 reports). Lead species Dog (555). Lead co-reported drug Trilostane (178).

Read these counts as reporting volume, not risk: per our methodology, Lead co-reported drug Trilostane appears in filings alongside this reaction; that is association, not causation. Browse the full reactions index or the about page for how PlainBreed frames FDA CVM extracts.

Species Most Affected

Dog 555
Cat 135
Horse 19
Ferret 1
Human 1

Breeds Most Affected

Domestic Shorthair 92
Retriever - Labrador 48
Crossbred Canine/dog 48
Chihuahua 32
Terrier - Yorkshire 31
Shih Tzu 24
Schnauzer - Miniature 22
Retriever - Golden 21
Maltese 18
Schnauzer (unspecified) 17

Associated Drugs

Trilostane 178
Oclacitinib Maleate 59
Carprofen 47
Bexagliflozin 47
Velagliflozin Proline Monohydrate 38
Milbemycin Oxime + Spinosad 35
Gabapentin 33
Afoxolaner 32
Prednisone 29
Ivermectin + Pyrantel As Pamoate Salt 27
Fluralaner Chew Tablets 27
Bedinvetmab 27
Maropitant Citrate 23
Cefovecin 20
Insulin Injectable Vial 20
Grapiprant 19
Spinosad 17
Anti-Il31 Mab Mcs Lot #1283563 17
Cyclosporine 16
Fluralaner 13.64% 12-Week Chew 14

Nationwide reactions with similar profiles

Two openFDA-derived peer sets for Elevated triglyceride, both floored at ≥50 reports so the neighborhoods stay in the advertised mass (the volume chart above is the unfloored photo-finish strip).

Similar death-coded share

Nearest other reactions by death-coded share (14.2% here), distinct from the volume row.

What to do with this reaction

A report does not prove a drug caused the reaction; consult a veterinarian before acting on this data.

Source: FDA Center for Veterinary Medicine openFDA Animal & Veterinary Adverse Events (CVM AER) · 2025

openFDA Animal & Veterinary Adverse Events (FDA CVM) for Elevated triglyceride (#507 of 2,481 by report volume); death-coded 14.2%. PlainBreed reaction plate · death-coded report count stamp 101 · vintage 2025.

Informational only. FDA adverse-event reports are voluntary and do not prove causation; consult a veterinarian before acting on them. Verify with FDA CVM →