Elevated triglyceride

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VeDDRA Code: 2508

630 adverse event reports referencing this reaction

630
Total Reports
90
Deaths
1430.0%
Death Rate

Species Most Affected

Dog 512
Cat 101
Horse 15
Ferret 1
Human 1

Breeds Most Affected

Domestic Shorthair 67
Crossbred Canine/dog 43
Retriever - Labrador 42
Chihuahua 29
Terrier - Yorkshire 29
Retriever - Golden 21
Shih Tzu 21
Schnauzer - Miniature 21
Maltese 18
Schnauzer (unspecified) 17

Associated Drugs

Trilostane 165
Oclacitinib Maleate 48
Carprofen 43
Bexagliflozin 36
Milbemycin Oxime + Spinosad 35
Afoxolaner 28
Prednisone 27
Fluralaner Chew Tablets 27
Ivermectin + Pyrantel As Pamoate Salt 26
Gabapentin 22
Bedinvetmab 21
Velagliflozin Proline Monohydrate 20
Maropitant Citrate 19
Insulin Injectable Vial 19
Grapiprant 18
Spinosad 17
Cefovecin 17
Anti-Il31 Mab Mcs Lot #1283563 17
Cyclosporine 16
Meloxicam 13

Data Summary

Metric Value
Total reports referencing reaction 630
Reports with fatal outcome 90
Case-fatality rate (reported events) 1430.0%
Species observed 5
Breeds observed 20
Drugs associated with reaction 20

Source: FDA Center for Veterinary Medicine — Adverse Event Reporting (CVM AER); reaction term coded under VeDDRA 2508.

Elevated triglyceride Reaction Insights

The FDA Center for Veterinary Medicine database currently lists 630 adverse event reports that reference Elevated triglyceride as a reaction term, including 90 reports with a death outcome — a 1430.0% case-fatality figure calculated across only those events where this reaction was coded. The reaction is indexed in the openFDA system under VeDDRA code 2508, the standardized veterinary dictionary used to normalize clinical signs across submitters. Because reports are voluntary and often describe multiple concurrent signs per animal, the volume here reflects reporting intensity rather than true incidence in the broader pet population.

Elevated triglyceride appears most frequently in reports for Dog (512 reports), Cat (101 reports), Horse (15 reports) — with Dog dominating at 512 entries. Within those species, the breeds most often named alongside this reaction are Domestic Shorthair (67), Crossbred Canine/dog (43), Retriever - Labrador (42). These distributions are influenced both by underlying breed popularity and by how veterinarians and owners code a given clinical sign, so they should be interpreted as a reporting fingerprint rather than a pure susceptibility ranking.

The drugs most commonly co-reported with Elevated triglyceride are Trilostane (165 reports), Oclacitinib Maleate (48 reports), Carprofen (43 reports), Bexagliflozin (36 reports), with Trilostane appearing alongside this reaction in 165 submissions. Co-reporting does not establish that any specific product caused the reaction — FDA CVM data captures temporal association only. The value of these aggregates is in flagging which therapeutic classes appear repeatedly alongside a given clinical sign, so owners and veterinarians can ask targeted questions about medications currently in use.

Source: FDA Center for Veterinary Medicine — Adverse Event Reports FDA Center for Veterinary Medicine — Adverse Event Reports Data reflects voluntary submissions and may not represent actual incidence rates

Related

Data sourced from official AKC, AVMA, ACVO, and breed-club veterinary references. See our methodology for details. Retrieved and formatted by PlainBreed Editorial