Reaction profile

The FDA adverse-event record for elevated triglyceride

630 FDA adverse-event reports reference elevated triglyceride (VeDDRA 2508). See the species, breeds, and drugs most associated with it below.

630
reports citing this reaction
14.3%
death-coded share
Dog
most-affected species
Trilostane
most-associated drug
Verify with FDA CVM →
630
Total Reports
90
Deaths
14.3%
Death Rate

Species Most Affected

Dog 512
Cat 101
Horse 15
Ferret 1
Human 1

Breeds Most Affected

Domestic Shorthair 67
Crossbred Canine/dog 43
Retriever - Labrador 42
Chihuahua 29
Terrier - Yorkshire 29
Retriever - Golden 21
Shih Tzu 21
Schnauzer - Miniature 21
Maltese 18
Schnauzer (unspecified) 17

Associated Drugs

Trilostane 165
Oclacitinib Maleate 48
Carprofen 43
Bexagliflozin 36
Milbemycin Oxime + Spinosad 35
Afoxolaner 28
Prednisone 27
Fluralaner Chew Tablets 27
Ivermectin + Pyrantel As Pamoate Salt 26
Gabapentin 22
Bedinvetmab 21
Velagliflozin Proline Monohydrate 20
Maropitant Citrate 19
Insulin Injectable Vial 19
Grapiprant 18
Spinosad 17
Cefovecin 17
Anti-Il31 Mab Mcs Lot #1283563 17
Cyclosporine 16
Meloxicam 13

Elevated triglyceride Reaction Insights

630 reports name Elevated triglyceride; 90 recorded a death outcome (14.3% of reported events, not a population-level mortality rate). VeDDRA code: 2508.

By species: Dog (512 reports), Cat (101 reports), Horse (15 reports). By breed: Domestic Shorthair (67), Crossbred Canine/dog (43), Retriever - Labrador (42).

Most co-reported drugs: Trilostane (165 reports), Oclacitinib Maleate (48 reports), Carprofen (43 reports), Bexagliflozin (36 reports).

Read these counts as reporting volume, not risk: per our methodology, co-reporting reflects temporal association captured in voluntary submissions, not proof that a drug caused this reaction. A widely-prescribed drug will rack up more raw co-reports at an identical true rate than a rarely-used one, so compare within similar-exposure products.

Source: FDA Center for Veterinary Medicine openFDA Animal & Veterinary Adverse Events (CVM AER) · 2025

Every figure on PlainBreed is rendered directly from FDA openFDA adverse event data, no number is typed in by an editor. This page draws directly on FDA openFDA data, no figure is typed in by an editor. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.