Reaction profile

The FDA adverse-event record for red eye

619 FDA reports name red eye, a high-volume reaction in the CVM extract (VeDDRA 1721). Plate stamps and neighbourhood peers follow.

#564 of 2,481
by report volume (all reactions)
619
reports citing this reaction
6.5%
death-coded share
Dog
most-affected species

Release-over-release change

What changed in the latest FDA data snapshot

PlainBreed reconstructed the prior snapshot from dated openFDA partitions through 2025 Q4, then compared it with the 2026-07-27 openFDA export. Red eye has 619 reports now versus 606 in that prior snapshot: 13 more (2.1%).

Report change
+13
Death-coded reports
+2
Death-coded share
+0.2 pts

This compares reported-event counts in two source snapshots. It does not establish a change in real-world risk, product safety, or disease incidence.

Subscribe to Red eye changes

FDA AER · VeDDRA plate

Code 1721 VOL-MID

VOL-MID · DEATH-PAR · UPPER-Q · PHOTO-FINISH · SPECIES-DOG · DRUG-LEAD · DESK-WIDE · BOOK-FULL

  • VOL-MID 619 reports
  • DEATH-PAR 6.5%
  • UPPER-Q #564/2481
  • PHOTO-FINISH Cataract
  • SPECIES-DOG Dog · 535
  • DRUG-LEAD Milbemycin Oxime… · 110
  • DESK-WIDE 20 breeds
  • BOOK-FULL 8/8 fields

Nearest volume peer: Cataract (±0 reports)

Upper-third report volume drives the scale stamps on this plate; death-coded share and co-report peers follow. Not a clinical diagnosis.

High-volume neighbourhood around Red eye

Upper-third volume poles plus nearest peers, not a full reaction corpus board reprint.

Vomiting · highest174348Increased salivation · near622Head tilt - neurologi… · near621Cataract · near619Red eye · this reaction619Enlarged liver · near617Urinary tract neoplas… · low…10
FDA AER report volume · neighbourhood around Red eye

Red eye: low death-coded share in the FDA AER plate

Signature read: 619 reports place Red eye in the upper third of FDA AER volume (#564 of 2,481). Report volume is upper-third scale: 619 named reports in the openFDA extract. Death-coded share is lower-third: 40 of 619 reports (6.5% of named reports). Nearest volume peer: Cataract (±0 reports). Lead species Dog (535). Lead co-reported drug Milbemycin Oxime + Spinosad (110).

Read these counts as reporting volume, not risk: per our methodology, Lead co-reported drug Milbemycin Oxime + Spinosad appears in filings alongside this reaction; that is association, not causation. Browse the full reactions index or the about page for how PlainBreed frames FDA CVM extracts.

Species Most Affected

Dog 535
Cat 49
Human 34
Horse 1

Breeds Most Affected

Retriever - Labrador 59
Crossbred Canine/dog 45
Boxer (German Boxer) 35
Unknown 34
Domestic Shorthair 32
Retriever - Golden 27
Pit Bull 21
Shih Tzu 19
Terrier - Bull - American Pit 17
Chihuahua 17

Associated Drugs

Milbemycin Oxime + Spinosad 110
Moxidectin 67
Afoxolaner 46
Pyrantel Pamoate;Sarolaner 28
Florfenicol + Mometasone Furoate + Terbinafine Hydrochloride 27
Oclacitinib Maleate 26
Ivermectin + Pyrantel As Pamoate Salt 25
Spinosad 21
Milbemycin Oxime + Praziquantel 21
Maropitant Citrate 19
Rabies Vaccine 16
Imidacloprid + Moxidectin 16
Prednisone 16
Fluralaner Chew Tablets 14
Lotilaner 14
Bedinvetmab 13
Diphenhydramine 12
Carprofen 12
Insulin Injectable Vial 12
Gabapentin 12

Nationwide reactions with similar profiles

Two openFDA-derived peer sets for Red eye, both floored at ≥50 reports so the neighborhoods stay in the advertised mass (the volume chart above is the unfloored photo-finish strip).

Similar report volume

Nearest other reactions by FDA report count (619 here).

Similar death-coded share

Nearest other reactions by death-coded share (6.5% here), distinct from the volume row.

What to do with this reaction

A report does not prove a drug caused the reaction; consult a veterinarian before acting on this data.

Source: FDA Center for Veterinary Medicine openFDA Animal & Veterinary Adverse Events (CVM AER) · 2025

openFDA Animal & Veterinary Adverse Events (FDA CVM) for Red eye (#564 of 2,481 by report volume); death-coded 6.5%. PlainBreed reaction plate · report volume stamp 619 · vintage 2025.

Informational only. FDA adverse-event reports are voluntary and do not prove causation; consult a veterinarian before acting on them. Verify with FDA CVM →