Reaction profile

The FDA adverse-event record for blood clot

159 FDA adverse-event reports reference blood clot (VeDDRA 153). Plate codes and volume neighbourhood below; species, breeds, and drugs follow.

#1154 of 2,481
by report volume (all reactions)
159
reports citing this reaction
54.1%
death-coded share
Dog
most-affected species

Release-over-release change

What changed in the latest FDA data snapshot

PlainBreed reconstructed the prior snapshot from dated openFDA partitions through 2025 Q4, then compared it with the 2026-07-27 openFDA export. Blood clot has 159 reports now versus 155 in that prior snapshot: 4 more (2.6%).

Report change
+4
Death-coded reports
+1
Death-coded share
−0.8 pts

This compares reported-event counts in two source snapshots. It does not establish a change in real-world risk, product safety, or disease incidence.

Subscribe to Blood clot changes

FDA AER · VeDDRA plate

Code 153 VOL-LOW

VOL-LOW · DEATH-HOT · MID-PACK · PHOTO-FINISH · SPECIES-DOG · DRUG-LEAD · DESK-WIDE · BOOK-FULL

  • VOL-LOW 159 reports
  • DEATH-HOT 54.1%
  • MID-PACK #1154/2481
  • PHOTO-FINISH Application site dry…
  • SPECIES-DOG Dog · 109
  • DRUG-LEAD Maropitant Citrate · 20
  • DESK-WIDE 20 breeds
  • BOOK-FULL 8/8 fields

Nearest volume peer: Application site dry skin (±1 reports)

Upper-third death-coded share drives the outcome stamps on this plate; volume band, corpus rank, and co-report peers follow. Not a clinical diagnosis.

Report-volume neighbourhood around Blood clot

Highest and lowest poles plus nearest volume peers, not a full 2,500-reaction corpus board reprint.

Vomiting · highest174348Belching · near160Blood clot · this reaction159Application site dry… · near158Application site infe… · near158Low tear flow · near158Urinary tract neoplas… · low…10
FDA AER report volume · neighbourhood around Blood clot

Blood clot: high death-coded share in the FDA AER plate

Signature read: Blood clot's 54.1% death-coded share is among the highest in the openFDA reaction corpus. Report volume sits in the middle third of the reaction corpus. Death-coded share is upper-third: 86 of 159 reports (54.1% of named reports). Nearest volume peer: Application site dry skin (±1 reports). Lead species Dog (109). Lead co-reported drug Maropitant Citrate (20).

Read these counts as reporting volume, not risk: per our methodology, A high death-coded share in FDA filings does not prove causation; co-reporting is voluntary temporal association only. Browse the full reactions index or the about page for how PlainBreed frames FDA CVM extracts.

Species Most Affected

Dog 109
Cat 42
Human 2
Cattle 2
Horse 2
Sheep 1
Snake 1

Breeds Most Affected

Domestic Shorthair 24
Retriever - Labrador 10
Maltese 6
Dog (unknown) 6
Shih Tzu 5
Terrier - Bull - American Pit 5
Retriever - Golden 5
Terrier - Jack Russell 4
Shepherd Dog - German 4
Chihuahua 4

Associated Drugs

Maropitant Citrate 20
Bedinvetmab 15
Carprofen 14
Prednisone 14
Robenacoxib 14
Trilostane 13
Milbemycin Oxime + Spinosad 12
Buprenorphine 11
Enrofloxacin 10
Gabapentin 10
Isoflurane 10
Spinosad 9
Rabies Vaccine 9
Meloxicam 8
Doxycycline 8
Moxidectin 7
Sucralfate 7
Butorphanol 7
Famotidine 7
Omeprazole 7

Nationwide reactions with similar profiles

Two openFDA-derived peer sets for Blood clot, both floored at ≥50 reports so the neighborhoods stay in the advertised mass (the volume chart above is the unfloored photo-finish strip).

Similar report volume

Nearest other reactions by FDA report count (159 here).

Similar death-coded share

Nearest other reactions by death-coded share (54.1% here), distinct from the volume row.

What to do with this reaction

A report does not prove a drug caused the reaction; consult a veterinarian before acting on this data.

Source: FDA Center for Veterinary Medicine openFDA Animal & Veterinary Adverse Events (CVM AER) · 2025

openFDA Animal & Veterinary Adverse Events (FDA CVM) for Blood clot (#1154 of 2,481 by report volume); death-coded 54.1%. PlainBreed reaction plate · death-coded share stamp 54.1% · vintage 2025.

Informational only. FDA adverse-event reports are voluntary and do not prove causation; consult a veterinarian before acting on them. Verify with FDA CVM →