Reaction profile

The FDA adverse-event record for blood clot

147 FDA adverse-event reports reference blood clot (VeDDRA 153). See the species, breeds, and drugs most associated with it below.

147
reports citing this reaction
53.7%
death-coded share
Dog
most-affected species
Maropitant Citrate
most-associated drug
Verify with FDA CVM →
147
Total Reports
79
Deaths
53.7%
Death Rate

Species Most Affected

Dog 103
Cat 36
Human 2
Cattle 2
Horse 2
Sheep 1
Snake 1

Breeds Most Affected

Domestic Shorthair 20
Retriever - Labrador 10
Maltese 6
Dog (unknown) 6
Shih Tzu 5
Terrier - Bull - American Pit 5
Terrier - Jack Russell 4
Retriever - Golden 4
Unknown 3
Terrier - Yorkshire 3

Associated Drugs

Maropitant Citrate 18
Carprofen 13
Trilostane 13
Robenacoxib 13
Milbemycin Oxime + Spinosad 12
Prednisone 12
Bedinvetmab 12
Buprenorphine 10
Spinosad 9
Enrofloxacin 9
Isoflurane 9
Doxycycline 8
Meloxicam 8
Moxidectin 7
Famotidine 7
Rabies Vaccine 7
Omeprazole 7
Afoxolaner 7
Sucralfate 6
Butorphanol 6

Blood clot Reaction Insights

147 reports name Blood clot; 79 recorded a death outcome (53.7% of reported events, not a population-level mortality rate). VeDDRA code: 153.

By species: Dog (103 reports), Cat (36 reports), Human (2 reports). By breed: Domestic Shorthair (20), Retriever - Labrador (10), Maltese (6).

Most co-reported drugs: Maropitant Citrate (18 reports), Carprofen (13 reports), Trilostane (13 reports), Robenacoxib (13 reports).

Read these counts as reporting volume, not risk: per our methodology, co-reporting reflects temporal association captured in voluntary submissions, not proof that a drug caused this reaction. A widely-prescribed drug will rack up more raw co-reports at an identical true rate than a rarely-used one, so compare within similar-exposure products.

Source: FDA Center for Veterinary Medicine openFDA Animal & Veterinary Adverse Events (CVM AER) · 2025

Every figure on PlainBreed is rendered directly from FDA openFDA adverse event data, no number is typed in by an editor. This page draws directly on FDA openFDA data, no figure is typed in by an editor. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.