Reaction profile

The FDA adverse-event record for vacant

21 FDA reports name vacant, a lower-volume reaction in the CVM extract (VeDDRA 2636). Plate stamps and neighbourhood peers follow.

#2153 of 2,481
by report volume (all reactions)
21
reports citing this reaction
14.3%
death-coded share
Dog
most-affected species

Release-over-release change

What changed in the latest FDA data snapshot

PlainBreed reconstructed the prior snapshot from dated openFDA partitions through 2025 Q4, then compared it with the 2026-07-27 openFDA export. Vacant has 21 reports now versus 19 in that prior snapshot: 2 more (10.5%).

Report change
+2
Death-coded reports
+1
Death-coded share
+3.8 pts

This compares reported-event counts in two source snapshots. It does not establish a change in real-world risk, product safety, or disease incidence.

Subscribe to Vacant changes

FDA AER · VeDDRA plate

Code 2636 VOL-TRACE

VOL-TRACE · DEATH-ELEV · LOWER-Q · PHOTO-FINISH · SPECIES-DOG · DRUG-LEAD · DESK-WIDE · BOOK-FULL

  • VOL-TRACE 21 reports
  • DEATH-ELEV 14.3%
  • LOWER-Q #2153/2481
  • PHOTO-FINISH Chewing - pruritus
  • SPECIES-DOG Dog · 14
  • DRUG-LEAD Unspecified · 17
  • DESK-WIDE 11 breeds
  • BOOK-FULL 8/8 fields

Nearest volume peer: Chewing - pruritus (±0 reports)

Instrument codes from this reaction’s FDA CVM adverse-event extract: volume band, death-coded share, corpus rank, photo-finish peer, lead species, lead drug, breed desk, and book completeness. Not a clinical diagnosis.

Lower-volume neighbourhood around Vacant

Lower-third volume poles plus nearest peers, not a full reaction corpus board reprint.

Vomiting · highest174348Chewing - pruritus · near21Deterioration of musc… · near21External teat disorder · near21Heart disorder aggrav… · near21Vacant · this reaction21Urinary tract neoplas… · low…10
FDA AER report volume · neighbourhood around Vacant

What the FDA AER plate says about Vacant

Signature read: 21 reports place Vacant in the lower third of FDA AER volume (#2153 of 2,481). Report volume is lower-third scale: 21 named reports in the openFDA extract. 3 of 21 reports were death-coded (14.3% of named reports, not a population mortality rate). Nearest volume peer: Chewing - pruritus (±0 reports). Lead species Dog (14). Lead co-reported drug Unspecified (17).

Read these counts as reporting volume, not risk: per our methodology, Lead co-reported drug Unspecified appears in filings alongside this reaction; that is association, not causation. Browse the full reactions index or the about page for how PlainBreed frames FDA CVM extracts.

Species Most Affected

Dog 14
Cat 7

Breeds Most Affected

Crossbred Canine/dog 4
Domestic Shorthair 4
Chihuahua 3
Beagle 2
Cat (unknown) 2
Retriever - Labrador 1
Cat (other) 1
Poodle (unspecified) 1
Spaniel (unspecified) 1
Ridgeback - Rhodesian 1

Associated Drugs

Unspecified 17
Robenacoxib 4
Fluralaner Chew Tablets 3
Fluralaner 13.64% 12-Week Chew 3
Buprenorphine 3
Propofol 3
Meloxicam 3
Trilostane 2
Phenobarbital 2
Cefovecin Sodium 2
Amoxicillin Trihydrate;Clavulanate Potassium ( K-Clavulanate) 2
Isoflurane 2
Milbemycin Oxime + Spinosad 1
Ivermectin + Pyrantel 1
Ivermectin / Pyrantel Tablets 1
Spinosad 1
Sarolaner 1
Same 1
Selamectin 1
Polysulfated Glycosaminoglycan 1

What to do with this reaction

A report does not prove a drug caused the reaction; consult a veterinarian before acting on this data.

Source: FDA Center for Veterinary Medicine openFDA Animal & Veterinary Adverse Events (CVM AER) · 2025

openFDA Animal & Veterinary Adverse Events (FDA CVM) for Vacant (#2153 of 2,481 by report volume); death-coded 14.3%. PlainBreed reaction plate · report volume stamp 21 · vintage 2025.

Informational only. FDA adverse-event reports are voluntary and do not prove causation; consult a veterinarian before acting on them. Verify with FDA CVM →