Reaction profile

The FDA adverse-event record for vacant

18 FDA adverse-event reports reference vacant (VeDDRA 2636). See the species, breeds, and drugs most associated with it below.

18
reports citing this reaction
11.1%
death-coded share
Dog
most-affected species
Unspecified
most-associated drug
Verify with FDA CVM →
18
Total Reports
2
Deaths
11.1%
Death Rate

Species Most Affected

Dog 14
Cat 4

Breeds Most Affected

Crossbred Canine/dog 4
Chihuahua 3
Beagle 2
Domestic Shorthair 2
Retriever - Labrador 1
Cat (other) 1
Poodle (unspecified) 1
Spaniel (unspecified) 1
Ridgeback - Rhodesian 1
Boxer (German Boxer) 1

Associated Drugs

Unspecified 17
Fluralaner Chew Tablets 3
Fluralaner 13.64% 12-Week Chew 3
Trilostane 2
Phenobarbital 2
Propofol 2
Amoxicillin Trihydrate;Clavulanate Potassium ( K-Clavulanate) 2
Meloxicam 2
Robenacoxib 2
Buprenorphine 2
Cefovecin Sodium 2
Milbemycin Oxime + Spinosad 1
Ivermectin + Pyrantel 1
Ivermectin / Pyrantel Tablets 1
Spinosad 1
Sarolaner 1
Same 1
Polysulfated Glycosaminoglycan 1
Levothyroxine 1
Phenylpropanolamine 1

Vacant Reaction Insights

18 reports name Vacant; 2 recorded a death outcome (11.1% of reported events, not a population-level mortality rate). VeDDRA code: 2636.

By species: Dog (14 reports), Cat (4 reports). By breed: Crossbred Canine/dog (4), Chihuahua (3), Beagle (2).

Most co-reported drugs: Unspecified (17 reports), Fluralaner Chew Tablets (3 reports), Fluralaner 13.64% 12-Week Chew (3 reports), Trilostane (2 reports).

Read these counts as reporting volume, not risk: per our methodology, co-reporting reflects temporal association captured in voluntary submissions, not proof that a drug caused this reaction. A widely-prescribed drug will rack up more raw co-reports at an identical true rate than a rarely-used one, so compare within similar-exposure products.

Source: FDA Center for Veterinary Medicine openFDA Animal & Veterinary Adverse Events (CVM AER) · 2025

Every figure on PlainBreed is rendered directly from FDA openFDA adverse event data, no number is typed in by an editor. This page draws directly on FDA openFDA data, no figure is typed in by an editor. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.